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The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…

Quantitative Methods · Quantitative Biology 2025-12-10 Xiao Yuan

Adversarial training is a technique of improving model performance by involving adversarial examples in the training process. In this paper, we investigate adversarial training with multiple adversarial examples to benefit the relation…

Computation and Language · Computer Science 2020-09-28 Peng Su , K. Vijay-Shanker

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

Contrastive Learning first extracts features from unlabeled data, followed by linear probing with labeled data. Adversarial Contrastive Learning (ACL) integrates Adversarial Training into the first phase to enhance feature robustness…

Machine Learning · Computer Science 2025-10-28 Ngoc N. Tran , Lam Tran , Hoang Phan , Anh Bui , Tung Pham , Toan Tran , Dinh Phung , Trung Le

In many applications labeled data is not readily available, and needs to be collected via pain-staking human supervision. We propose a rule-exemplar method for collecting human supervision to combine the efficiency of rules with the quality…

Machine Learning · Computer Science 2020-05-18 Abhijeet Awasthi , Sabyasachi Ghosh , Rasna Goyal , Sunita Sarawagi

The citation network of patents citing prior art arises from the legal obligation of patent applicants to properly disclose their invention. One way to study the relationship between current patents and their antecedents is by analyzing the…

Applications · Statistics 2023-04-26 Edoardo Filippi-Mazzola , Federica Bianchi , Ernst C. Wit

We propose methods to strengthen the invariance properties of representations obtained by contrastive learning. While existing approaches implicitly induce a degree of invariance as representations are learned, we look to more directly…

Machine Learning · Computer Science 2021-03-23 Adam Foster , Rattana Pukdee , Tom Rainforth

Current patent claim generation systems face three fundamental limitations: poor cross-jurisdictional generalization, inadequate semantic relationship modeling between claims and prior art, and unreliable quality assessment. We introduce a…

Computation and Language · Computer Science 2026-01-15 Chen-Wei Liang , Bin Guo , Zhen-Yuan Wei , Mu-Jiang-Shan Wang

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

The inability of artificial neural networks to assess the uncertainty of their predictions is an impediment to their widespread use. We distinguish two types of learnable uncertainty: model uncertainty due to a lack of training data and…

Machine Learning · Computer Science 2022-06-14 Hans Weytjens , Jochen De Weerdt

For a real-world decision-making problem, the reward function often needs to be engineered or learned. A popular approach is to utilize human feedback to learn a reward function for training. The most straightforward way to do so is to ask…

Machine Learning · Computer Science 2023-10-31 Xiang Ji , Huazheng Wang , Minshuo Chen , Tuo Zhao , Mengdi Wang

People's decision-making abilities often fail to improve or may even erode when they rely on AI for decision-support, even when the AI provides informative explanations. We argue this is partly because people intuitively seek contrastive…

Human-Computer Interaction · Computer Science 2025-03-20 Zana Buçinca , Siddharth Swaroop , Amanda E. Paluch , Finale Doshi-Velez , Krzysztof Z. Gajos

Adversarial training has become the primary method to defend against adversarial samples. However, it is hard to practically apply due to many shortcomings. One of the shortcomings of adversarial training is that it will reduce the…

Machine Learning · Computer Science 2021-08-31 Zhishen Nie , Ying Lin , Sp Ren , Lan Zhang

Recent research studies revealed that neural networks are vulnerable to adversarial attacks. State-of-the-art defensive techniques add various adversarial examples in training to improve models' adversarial robustness. However, these…

Machine Learning · Computer Science 2019-09-13 Chang Song , Zuoguan Wang , Hai Li

Recently, adversarial machine learning attacks have posed serious security threats against practical audio signal classification systems, including speech recognition, speaker recognition, and music copyright detection. Previous studies…

Sound · Computer Science 2022-07-28 Rui Duan , Zhe Qu , Shangqing Zhao , Leah Ding , Yao Liu , Zhuo Lu

Deep neural network models can learn clinically relevant features from millions of histopathology images. However generating high-quality annotations to train such models for each hospital, each cancer type, and each diagnostic task is…

The rapid development in data collecting devices and computation platforms produces an emerging number of agents, each equipped with a unique data modality over a particular population of subjects. While the predictive performance of an…

Machine Learning · Computer Science 2020-10-22 Jiaying Zhou , Xun Xian , Na Li , Jie Ding

Predicting cross-immunity between viral strains is vital for public health surveillance and vaccine development. Traditional neural network methods, such as BiLSTM, could be ineffective due to the lack of lab data for model training and the…

Computational Engineering, Finance, and Science · Computer Science 2023-10-18 Yiming Du , Zhuotian Li , Qian He , Thomas Wetere Tulu , Kei Hang Katie Chan , Lin Wang , Sen Pei , Zhanwei Du , Xiao-Ke Xu , Xiao Fan Liu

Adversarial training is an effective learning technique to improve the robustness of deep neural networks. In this study, the influence of adversarial training on deep learning models in terms of fairness, robustness, and generalization is…

Machine Learning · Computer Science 2023-05-19 Xiaoling Zhou , Nan Yang , Ou Wu

Reliable models should not only predict correctly, but also justify decisions with acceptable evidence. Yet conventional supervised learning typically provides only class-level labels, allowing models to achieve high accuracy through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Ruoyu Chen , Shangquan Sun , Xiaoqing Guo , Sanyi Zhang , Kangwei Liu , Shiming Liu , Zhangcheng Wang , Qunli Zhang , Hua Zhang , Xiaochun Cao