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Digital twins (DTs) are redefining healthcare by paving the way for more personalized, proactive, and intelligent medical interventions. As the shift toward personalized care intensifies, there is a growing need for an individual's virtual…

Human-Computer Interaction · Computer Science 2025-03-18 Melvin Mokhtari

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

Human-Computer Interaction · Computer Science 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

Medical Physics · Physics 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

Recently, Artificial Intelligence (AI)-based algorithms have revolutionized the medical image segmentation processes. Thus, the precise segmentation of organs and their lesions may contribute to an efficient diagnostics process and a more…

Neurons and Cognition · Quantitative Biology 2024-03-21 Zofia Rudnicka , Janusz Szczepanski , Agnieszka Pregowska

Digital twin has recently attracted growing attention, leading to intensive research and applications. Along with this, a new research area, dubbed as "human digital twin" (HDT), has emerged. Similar to the conception of digital twin, HDT…

Human-Computer Interaction · Computer Science 2022-12-13 Yujia Lin , Liming Chen , Aftab Ali , Christopher Nugent , Cleland Ian , Rongyang Li , Dazhi Gao , Hang Wang , Yajie Wang , Huansheng Ning

Human Digital Twins (HDTs) are digital replicas of humans that either mirror a complete human body, some parts of it as can be organs, flows, cells, or even human behaviors. An HDT is a human specific replica application inferred from the…

Other Computer Science · Computer Science 2023-02-08 Heribert Pascual , Xavi Masip Bruin , Albert Alonso , Judit Cerdà

Digital twin (DT), refers to a promising technique to digitally and accurately represent actual physical entities. One typical advantage of DT is that it can be used to not only virtually replicate a system's detailed operations but also…

Networking and Internet Architecture · Computer Science 2023-09-08 Jiayuan Chen , Changyan Yi , Samuel D. Okegbile , Jun Cai , Xuemin , Shen

The Internet of things (IoT) can significantly enhance the quality of human life, specifically in healthcare, attracting extensive attentions to IoT-healthcare services. Meanwhile, the human digital twin (HDT) is proposed as an innovative…

Human-Computer Interaction · Computer Science 2024-07-01 Jiayuan Chen , You Shi , Changyan Yi , Hongyang Du , Jiawen Kang , Dusit Niyato

Synthetic digital twins based on medical data accelerate the acquisition, labelling and decision making procedure in digital healthcare. A core part of digital healthcare twins is model-based data synthesis, which permits the generation of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Xiaodan Xing , Javier Del Ser , Yinzhe Wu , Yang Li , Jun Xia , Lei Xu , David Firmin , Peter Gatehouse , Guang Yang

Recent advancements in artificial intelligence (AI) have revolutionized cardiovascular medicine, particularly through integration with computed tomography (CT), magnetic resonance imaging (MRI), electrocardiography (ECG) and ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Yuanlin Mo , Haishan Huang , Bocheng Liang , Weibo Ma

Human Digital Twins (HDTs) are a fast-emerging technology with significant potential in fields ranging from healthcare to sports. HDTs extend the traditional understanding of Digital Twins by representing humans as the underlying physical…

Human-Computer Interaction · Computer Science 2024-02-14 Martin Wolfgang Lauer-Schmaltz , Philip Cash , John Paulin Hansen , Anja Maier

With the accelerating availability of multimodal surgical data and real-time computation, Surgical Digital Twins (SDTs) have emerged as virtual counterparts that mirror, predict, and inform decisions across pre-, intra-, and postoperative…

Mobile Artificial Intelligence-Generated Content (AIGC) technology refers to the adoption of AI algorithms deployed at mobile edge networks to automate the information creation process while fulfilling the requirements of end users. Mobile…

Networking and Internet Architecture · Computer Science 2023-07-25 Jiayuan Chen , Changyan Yi , Hongyang Du , Dusit Niyato , Jiawen Kang , Jun Cai , Xuemin , Shen

The adoption of digital twins (DTs) in precision medicine is increasingly viable, propelled by extensive data collection and advancements in artificial intelligence (AI), alongside traditional biomedical methodologies. However, the reliance…

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level,…

Machine Learning · Computer Science 2024-05-14 Yaojun Hu , Jintai Chen , Lianting Hu , Dantong Li , Jiahuan Yan , Haochao Ying , Huiying Liang , Jian Wu

The combination of data and models, enhanced by AI methodologies, leads to the paradigm called Digital Twins. This concept is expected to bring unprecedented support to personalized medicine. The combination of mathematical and numerical…

Numerical Analysis · Mathematics 2026-04-29 Alessandro Veneziani , Annalisa Quaini , Marco Tezzele , Omer San , Traian Iliescu

Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…

Software Engineering · Computer Science 2026-02-13 Micheal P. Papazoglou , Bernd J. Krämer , Mira Raheem , Amal Elgammal

Cardiac digital twins (CDTs) are personalized virtual representations used to understand complex cardiac mechanisms. A critical component of CDT development is solving the ECG inverse problem, which enables the reconstruction of cardiac…

Computer Vision and Pattern Recognition · Computer Science 2024-09-16 Lei Li , Julia Camps , Blanca Rodriguez , Vicente Grau

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…

Artificial Intelligence · Computer Science 2024-04-24 Chenyu Tang , Wentian Yi , Edoardo Occhipinti , Yanning Dai , Shuo Gao , Luigi G. Occhipinti
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