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As high-throughput sequencers become standard equipment outside of sequencing centers, there is an increasing need for efficient methods for pre-processing and primary analysis. While a vast literature proposes methods for HTS data…

Computational Engineering, Finance, and Science · Computer Science 2014-04-11 Md Pavel Mahmud , Alexander Schliep

An error-corrected quantum processor will require millions of qubits, accentuating the advantage of nanoscale devices with small footprints, such as silicon quantum dots. However, as for every device with nanoscale dimensions, disorder at…

Using Grover algorithm, this work investigates a technique for encoding search phrases used in wildcard searches. The technique involves creating a phase Oracle that loads data into a quantum circuit together with the search terms that have…

Quantum Physics · Physics 2023-03-17 Willie Huang

DNA cloning methods are fundamental tools in molecular biology, synthetic biology, and genetic engineering that enable precise DNA manipulation for various scientific and biotechnological applications. This review systematically summarizes…

Biomolecules · Quantitative Biology 2025-05-07 Isabella Frighetto Bomfiglio , Isabelli Seiler de Medeiros Mendes , Diego Bonatto

An important step in building a quantum computer is calibrating experimentally implemented quantum gates to produce operations that are close to ideal unitaries. The calibration step involves estimating the systematic errors in gates and…

Quantum Physics · Physics 2021-10-22 Shelby Kimmel , Guang Hao Low , Theodore J. Yoder

The de novo assembly of large, complex genomes is a significant challenge with currently available DNA sequencing technology. While many de novo assembly software packages are available, comparatively little attention has been paid to…

Genomics · Quantitative Biology 2013-07-31 Jared T. Simpson

We propose genetic algorithms, which are robust optimization techniques inspired by natural selection, to enhance the versatility of digital quantum simulations. In this sense, we show that genetic algorithms can be employed to increase the…

Quantum Physics · Physics 2016-06-22 U. Las Heras , U. Alvarez-Rodriguez , E. Solano , M. Sanz

Any quantum program on a realistic quantum device must be compiled into an executable form while taking into account the underlying hardware constraints. Stringent restrictions on architecture and control imposed by physical platforms make…

Quantum Physics · Physics 2023-10-16 Run-Hong He , Xu-Sheng Xu , Mark S. Byrd , Zhao-Ming Wang

In a quantum computer, creating superpositions of quantum bits (qubits) in different states can lead to a speed-up over classical computers [1], but quantum mechanics also allows for the superposition of quantum circuits [2]. In fact, it…

Continuous gate sets are a key ingredient for near-term quantum algorithms. Here, we demonstrate a hardware-efficient, continuous set of controlled arbitrary-phase ($\mathrm{C}Z_{\theta}$) gates acting on flux-tunable transmon qubits. This…

Scalable, high-fidelity quantum-state readout remains a central challenge in the development of large-scale superconducting quantum processors. Conventional dispersive readout architectures depend on bulky isolators and external amplifiers,…

Quantum Physics · Physics 2026-02-17 Leon Bello , Boris Mesits , Michael Hatridge , Hakan E. Türeci

Shortening quantum circuits is crucial to reducing the destructive effect of environmental decoherence and enabling useful algorithms. Here, we demonstrate an improvement in such compilation tasks via a combination of using hybrid…

Credibility building activities in computational research include verification and validation, reproducibility and replication, and uncertainty quantification. Though orthogonal to each other, they are related. This paper presents…

Computational Physics · Physics 2021-04-28 Natalia C. Clementi , Lorena A. Barba

Quantum gates based on geometric phases possess intrinsic noise-resilience features and therefore attract much attention. However, the implementations of previous geometric quantum computation typically require a long pulse time of gates.…

Quantum Physics · Physics 2022-10-10 Zhuang Ma , Jianwen Xu , Tao Chen , Yu Zhang , Wen Zheng , Dong Lan , Zheng-Yuan Xue , Xinsheng Tan , Yang Yu

The physical limitations of CMOS technology triggered several research for finding an alternative technology. QCA is one of the emerging nanotechnologies which is gaining attention as a substitute of CMOS. The main potential of QCA is its…

Emerging Technologies · Computer Science 2017-05-12 Mahabub Hasan Mahalat , Mrinal Goswami , Anindan Mondal , Bibhash Sen

Nanopore sequencing is an emerging new technology for sequencing DNA, which can read long fragments of DNA (~50,000 bases) in contrast to most current short-read sequencing technologies which can only read hundreds of bases. While nanopore…

Information Theory · Computer Science 2018-02-20 Wei Mao , Suhas Diggavi , Sreeram Kannan

Unsupervised clustering algorithms for vectors has been widely used in the area of machine learning. Many applications, including the biological data we studied in this paper, contain some boundary datapoints which show combination…

Machine Learning · Computer Science 2022-05-23 Yingcong Li , Chandra Sekhar Mukherjee , Jiapeng Zhang

We report on experimental implementation of a machine-learned quantum gate driven by a classical control. The gate learns optimal phase-covariant cloning in a reinforcement learning scenario having fidelity of the clones as reward. In our…

We study a class of aggregate-join queries with multiple aggregation operators evaluated over annotated relations. We show that straightforward extensions of standard multiway join algorithms and generalized hypertree decompositions (GHDs)…

Databases · Computer Science 2015-12-11 Manas Joglekar , Rohan Puttagunta , Christopher Ré

Geometric phase is a promising element to induce high-fidelity and robust quantum operations due to its built-in noise-resilience feature. Unfortunately, its practical applications are usually circumscribed by requiring complex interactions…

Quantum Physics · Physics 2020-12-08 Tao Chen , Zheng-Yuan Xue
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