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Realizing edge intelligence consists of sensing, communication, training, and inference stages. Conventionally, the sensing and communication stages are executed sequentially, which results in excessive amount of dataset generation and…

Signal Processing · Electrical Eng. & Systems 2022-01-25 Tong Zhang , Shuai Wang , Guoliang Li , Fan Liu , Guangxu Zhu , Rui Wang

Bistability is considered wide-spread among bacteria and eukaryotic cells, useful e.g. for enzyme induction, bet hedging, and epigenetic switching. However, this phenomenon has mostly been described with deterministic dynamic or well-mixed…

Subcellular Processes · Quantitative Biology 2017-02-08 Robert G. Endres

Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed…

Microorganisms can create engineered materials with exquisite structures and living functionalities. Although synthetic biology tools to genetically manipulate microorganisms continue to expand, the bottom-up rational design of engineered…

The ability to monitor nutrient and other environmental conditions with high sensitivity is crucial for cell growth and survival. Sensory adaptation allows a cell to recover its sensitivity after a transient response to a shift in the…

Subcellular Processes · Quantitative Biology 2016-01-07 Shou-Wen Wang , Yueheng Lan , Lei-Han Tang

Wearable, implantable, and ingestible antennas are continuously evolving in biomedical applications, as they are crucial components in devices used for monitoring and controlling physiological parameters. This work presents an…

Systems and Control · Electrical Eng. & Systems 2024-11-20 Maria Koutsoupidou , Dimitrios C. Tzarouchis , Dionysios Rompolas , Ioannis Sotiriou , George Palikaras , Panagiotis Kosmas

Molecular communication is a novel approach for data transmission between miniaturized devices, especially in contexts where electrical signals are to be avoided. The communication is based on sending molecules (or other particles) at nano…

Emerging Technologies · Computer Science 2023-08-08 Max Bartunik , Jens Kirchner , Oliver Keszocze

In recent years, progresses in nanotechnology have established the foundations for implementing nanomachines capable of carrying out simple but significant tasks. Under this stimulus, researchers have been proposing various solutions for…

Emerging Technologies · Computer Science 2018-08-14 Luca Felicetti , Mauro Femminella , Gianluca Reali , Pietro Liò

The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…

Soft Condensed Matter · Physics 2024-02-20 Roman Golkov , Yair Shokef

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

Neurons and Cognition · Quantitative Biology 2017-09-14 Archana Ram , Andrew Lo

In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein enters a spherical cell and propagates via two competing…

Biological Physics · Physics 2009-11-11 Holger Merlitz , Konstantin V. Klenin , Chen-Xu Wu , Jörg Langowski

The simulation of transmission electron microscopy (TEM) images or diffraction patterns is often required to interpret their contrast and extract specimen features. This is especially true for high-resolution phase-contrast imaging of…

Materials Science · Physics 2021-03-30 Jacob Madsen , Timothy J. Pennycook , Toma Susi

The design of communication systems capable of processing and exchanging information through molecules and chemical processes is a rapidly growing interdisciplinary field, which holds the promise to revolutionize how we realize computing…

Emerging Technologies · Computer Science 2019-08-12 Dadi Bi , Yansha Deng , Massimiliano Pierobon , Arumugam Nallanathan

Adaptation mechanism of cells on the basis of stochastic gene expression and epigenetic modification is proposed. From marginally stable states generated by epigenetic modification, a gene expression pattern that achieves greater cell…

Molecular Networks · Quantitative Biology 2019-01-18 Yusuke Himeoka , Kunihiko Kaneko

We present a simple biophysical model for the coupling between synaptic transmission and the local calcium concentration on an enveloping astrocytic domain. This interaction enables the astrocyte to modulate the information flow from…

Neurons and Cognition · Quantitative Biology 2007-05-23 Vladislav Volman , Eshel Ben-Jacob , Herbert Levine

This thesis develops the theory of whispering gallery modes, exploring under what conditions a micro or nanoscale device can sustain these resonances, and for which physical criteria the resonance conditions deteriorate. The study is then…

Optics · Physics 2018-09-11 Jonathan M. M. Hall

Fertility monitoring in humans for either natural conception or artificial insemination and fertilization has been a critical challenge both for the treating physician and the treated patients. Eggs in human female can be fertilized when…

Signal Processing · Electrical Eng. & Systems 2022-02-07 Shama Siddiqui , Anwar Ahmed Khan , Qammer H. Abbasi , Muhammad Ali Imran , Indrakshi Dey

Cell-free wireless communication is envisioned as one of the most promising network architectures, which can achieve stable and uniform communication performance while improving the system energy and spectrum efficiency. The deployment of…

Signal Processing · Electrical Eng. & Systems 2024-06-05 Zhuoyin Dai , Jingran Xu , Xiaoli Xu , Ruoguang Li , Yong Zeng

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

This paper presents a software platform, named BiNS2, able to simulate diffusion-based molecular communications with drift inside blood vessels. The contribution of the paper is twofold. First a detailed description of the simulator is…

Computational Engineering, Finance, and Science · Computer Science 2013-08-16 Luca Felicetti , Mauro Femminella , Gianluca Reali