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Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Recent concept-based interpretable models have succeeded in providing meaningful explanations by pre-defined concept sets. However, the dependency on the pre-defined concepts restricts the application because of the limited number of…

Artificial Intelligence · Computer Science 2025-02-19 Shin'ya Yamaguchi , Kosuke Nishida

Concept Bottleneck Models (CBMs) introduce interpretability to black-box deep learning models by predicting labels through human-understandable concepts. However, unlike humans, who identify objects at different levels of abstraction using…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Haodong Xie , Yujun Cai , Rahul Singh Maharjan , Yiwei Wang , Federico Tavella , Angelo Cangelosi

Concept bottleneck models (CBMs) ensure interpretability by decomposing predictions into human interpretable concepts. Yet the annotations used for training CBMs that enable this transparency are often noisy, and the impact of such…

Machine Learning · Computer Science 2026-02-02 Seonghwan Park , Jueun Mun , Donghyun Oh , Namhoon Lee

Recent advancements in post-hoc and inherently interpretable methods have markedly enhanced the explanations of black box classifier models. These methods operate either through post-analysis or by integrating concept learning during model…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Bor-Shiun Wang , Chien-Yi Wang , Wei-Chen Chiu

Catastrophic forgetting remains a fundamental challenge in continual learning, in which models often forget previous knowledge when fine-tuned on a new task. This issue is especially pronounced in class incremental learning (CIL), which is…

Machine Learning · Computer Science 2026-04-17 Amirhosein Javadi , Tuomas Oikarinen , Tara Javidi , Tsui-Wei Weng

Interpretable models are designed to make decisions in a human-interpretable manner. Representatively, Concept Bottleneck Models (CBM) follow a two-step process of concept prediction and class prediction based on the predicted concepts. CBM…

Machine Learning · Computer Science 2023-06-05 Eunji Kim , Dahuin Jung , Sangha Park , Siwon Kim , Sungroh Yoon

Concept Bottleneck Models (CBMs) provide inherent interpretability by first mapping input samples to high-level semantic concepts, followed by a combination of these concepts for the final classification. However, the annotation of…

Machine Learning · Computer Science 2026-03-02 Yangyi Li , Mengdi Huai

The rapid evolution of machine learning (ML) has led to the widespread adoption of complex "black box" models, such as deep neural networks and ensemble methods. These models exhibit exceptional predictive performance, making them…

Machine Learning · Computer Science 2025-03-28 Moncef Garouani , Josiane Mothe , Ayah Barhrhouj , Julien Aligon

The widespread adoption of deep learning models in computer vision has intensified concerns about interpretability. Despite strong performance, these models are often treated as black boxes, with limited systematic investigation of their…

Machine Learning · Computer Science 2026-05-13 Konstantinos P. Panousis , Diego Marcos

Concept-based models are an emerging paradigm in deep learning that constrains the inference process to operate through human-interpretable variables, facilitating explainability and human interaction. However, these architectures, on par…

Concept bottleneck models (CBMs) are inherently interpretable models that make predictions based on human-understandable visual cues, referred to as concepts. As obtaining dense concept annotations with human labeling is demanding and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sujin Jeon , Hyundo Lee , Eungseo Kim , Sanghack Lee , Byoung-Tak Zhang , Inwoo Hwang

We are concerned with the challenge of reliably classifying and assessing intracranial aneurysms using deep learning without compromising clinical transparency. While traditional black-box models achieve high predictive accuracy, their lack…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Toqa Khaled , Ahmad Al-Kabbany

Rising usage of deep neural networks to perform decision making in critical applications like medical diagnosis and financial analysis have raised concerns regarding their reliability and trustworthiness. As automated systems become more…

Machine Learning · Computer Science 2022-11-30 Sanchit Sinha , Mengdi Huai , Jianhui Sun , Aidong Zhang

The demand for reliable AI systems has intensified the need for interpretable deep neural networks. Concept bottleneck models (CBMs) have gained attention as an effective approach by leveraging human-understandable concepts to enhance…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Sangwon Kim , Dasom Ahn , Byoung Chul Ko , In-su Jang , Kwang-Ju Kim

Recently impressive performance has been achieved in Concept Bottleneck Models (CBM) by utilizing the image-text alignment learned by a large pre-trained vision-language model (i.e. CLIP). However, there exist two key limitations in concept…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Minghong Zhong , Guoshuai Zou , Kanghao Chen , Dexia Chen , Ruixuan Wang

Concept Bottleneck Models (CBMs) provide interpretable prediction by introducing an intermediate Concept Bottleneck Layer (CBL), which encodes human-understandable concepts to explain models' decision. Recent works proposed to utilize Large…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Divyansh Srivastava , Ge Yan , Tsui-Wei Weng

Appendicitis is among the most frequent reasons for pediatric abdominal surgeries. Previous decision support systems for appendicitis have focused on clinical, laboratory, scoring, and computed tomography data and have ignored abdominal…

Successful group meetings, such as those implemented in group behavioral-change programs, work meetings, and other social contexts, must promote individual goal setting and execution while strengthening the social relationships within the…

Computation and Language · Computer Science 2025-08-07 Xinyu Zhao , Zhen Tan , Maya Enisman , Minjae Seo , Marta R. Durantini , Dolores Albarracin , Tianlong Chen

Concept bottleneck models (CBM) aim to produce inherently interpretable models that rely on human-understandable concepts for their predictions. However, existing approaches to design interpretable generative models based on CBMs are not…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Akshay Kulkarni , Ge Yan , Chung-En Sun , Tuomas Oikarinen , Tsui-Wei Weng
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