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We show that unsupervised machine learning can be used to learn physical and chemical transformation pathways from the observational microscopic data, as demonstrated for atomically resolved images in Scanning Transmission Electron…

Modeling non-empirical and highly flexible interatomic potential energy surfaces (PES) using machine learning (ML) approaches is becoming popular in molecular and materials research. Training an ML-PES is typically performed in two stages:…

Materials Science · Physics 2021-01-05 Suresh Kondati Natarajan , Miguel A. Caro

Molecular property prediction is essential for drug discovery. In recent years, deep learning methods have been introduced to this area and achieved state-of-the-art performances. However, most of existing methods ignore the intrinsic…

Biomolecules · Quantitative Biology 2022-11-04 Yuancheng Sun , Yimeng Chen , Weizhi Ma , Wenhao Huang , Kang Liu , Zhiming Ma , Wei-Ying Ma , Yanyan Lan

In applications of machine learning to particle physics, a persistent challenge is how to go beyond discrimination to learn about the underlying physics. To this end, a powerful tool would be a framework for unsupervised learning, where the…

High Energy Physics - Phenomenology · Physics 2019-02-20 Anders Andreassen , Ilya Feige , Christopher Frye , Matthew D. Schwartz

We present a transformer architecture-based foundation model for tasks at high-energy particle colliders such as the Large Hadron Collider. We train the model to classify jets using a self-supervised strategy inspired by the Joint Embedding…

Machine Learning · Computer Science 2025-02-07 Jai Bardhan , Radhikesh Agrawal , Abhiram Tilak , Cyrin Neeraj , Subhadip Mitra

Existing 3D mask learning methods encounter performance bottlenecks under limited data, and our objective is to overcome this limitation. In this paper, we introduce a triple point masking scheme, named TPM, which serves as a scalable…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Jiaming Liu , Linghe Kong , Yue Wu , Maoguo Gong , Hao Li , Qiguang Miao , Wenping Ma , Can Qin

Graph neural networks (GNNs) have shown considerable promise in computational chemistry. However, the limited availability of molecular data raises concerns regarding GNNs' ability to effectively capture the fundamental principles of…

Machine Learning · Computer Science 2025-03-12 Junyi An , Chao Qu , Yun-Fei Shi , XinHao Liu , Qianwei Tang , Fenglei Cao , Yuan Qi

Masked Image Modeling (MIM) has achieved impressive representative performance with the aim of reconstructing randomly masked images. Despite the empirical success, most previous works have neglected the important fact that it is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Junde Xu , Zikai Lin , Donghao Zhou , Yaodong Yang , Xiangyun Liao , Bian Wu , Guangyong Chen , Pheng-Ann Heng

Recent general-purpose audio representations show state-of-the-art performance on various audio tasks. These representations are pre-trained by self-supervised learning methods that create training signals from the input. For example,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-09 Daisuke Niizumi , Daiki Takeuchi , Yasunori Ohishi , Noboru Harada , Kunio Kashino

Particle-based shape modeling (PSM) is a popular approach to automatically quantify shape variability in populations of anatomies. The PSM family of methods employs optimization to automatically populate a dense set of corresponding…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hong Xu , Shireen Y. Elhabian

A key question for machine learning approaches in particle physics is how to best represent and learn from collider events. As an event is intrinsically a variable-length unordered set of particles, we build upon recent machine learning…

High Energy Physics - Phenomenology · Physics 2020-04-17 Patrick T. Komiske , Eric M. Metodiev , Jesse Thaler

Masked image modeling is a promising self-supervised learning method for visual data. It is typically built upon image patches with random masks, which largely ignores the variation of information density between them. The question is: Is…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Haijian Chen , Wendong Zhang , Yunbo Wang , Xiaokang Yang

We introduce multiple physics pretraining (MPP), an autoregressive task-agnostic pretraining approach for physical surrogate modeling of spatiotemporal systems with transformers. In MPP, rather than training one model on a specific physical…

Machine Learning (ML) for Mineral Prospectivity Mapping (MPM) remains a challenging problem as it requires the analysis of associations between large-scale multi-modal geospatial data and few historical mineral commodity observations…

Machine Learning · Computer Science 2024-06-19 Angel Daruna , Vasily Zadorozhnyy , Georgina Lukoczki , Han-Pang Chiu

Self-supervised learning has transformed 2D computer vision by enabling models trained on large, unannotated datasets to provide versatile off-the-shelf features that perform similarly to models trained with labels. However, in 3D scene…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Pedro Hermosilla , Christian Stippel , Leon Sick

Particle physics or High Energy Physics (HEP) studies the elementary constituents of matter and their interactions with each other. Machine Learning (ML) has played an important role in HEP analysis and has proven extremely successful in…

Machine Learning · Computer Science 2019-12-18 Marouen Baalouch , Maxime Defurne , Jean-Philippe Poli , Noëlie Cherrier

Open-sourcing foundation models (FMs) enables broad reuse but also exposes model trainers to economic and safety risks from unrestricted downstream fine-tuning. We address this problem by building non-fine-tunable foundation models: models…

Machine Learning · Computer Science 2026-02-03 Ziyao Wang , Nizhang Li , Pingzhi Li , Guoheng Sun , Tianlong Chen , Ang Li

Human action recognition is a crucial task for intelligent robotics, particularly within the context of human-robot collaboration research. In self-supervised skeleton-based action recognition, the mask-based reconstruction paradigm learns…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Wei Wei , Shaojie Zhang , Yonghao Dang , Jianqin Yin

How to learn discriminative video representation from unlabeled videos is challenging but crucial for video analysis. The latest attempts seek to learn a representation model by predicting the appearance contents in the masked regions.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Xinyu Sun , Peihao Chen , Liangwei Chen , Changhao Li , Thomas H. Li , Mingkui Tan , Chuang Gan

Computational studies of chemical reactions in complex environments such as proteins, nanostructures, or on surfaces require accurate and efficient atomistic models applicable to the nanometer scale. In general, an accurate parametrization…

Chemical Physics · Physics 2020-02-18 Christoph Brunken , Markus Reiher