English
Related papers

Related papers: Understanding Cellular Noise with Optical Perturba…

200 papers

Photonic brain-inspired platforms are emerging as novel analog computing devices, enabling fast and energy-efficient operations for machine learning. These artificial neural networks generally require tailored optical elements, such as…

Emerging Technologies · Computer Science 2021-07-30 Davide Pierangeli , Giulia Marcucci , Claudio Conti

Understanding cell function requires an accurate description of how noise is transmitted through biochemical networks. We present an analytical result for the power spectrum of the output signal of a biochemical network that takes into…

Molecular Networks · Quantitative Biology 2009-11-11 Sorin Tanase-Nicola , Patrick B. Warren , Pieter Rein ten Wolde

Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…

Molecular Networks · Quantitative Biology 2007-05-23 Thimo Rohlf , Stefan Bornholdt

The inability of DNNs to explain their black-box behavior has led to a recent surge of explainability methods. However, there are growing concerns that these explainability methods are not robust and trustworthy. In this work, we perform…

Machine Learning · Computer Science 2023-10-26 Divyansh Srivastava , Tuomas Oikarinen , Tsui-Wei Weng

Examining individual components of cellular systems has been successful in uncovering molecular reactions and interactions. However, the challenge lies in integrating these components into a comprehensive system-scale map. This difficulty…

Other Quantitative Biology · Quantitative Biology 2024-07-03 Nima Dehghani

We develop a systems approach based on an energy-landscape concept to differentiate interactions involving redox activities and conformational changes of proteins and nucleic acids interactions in multi-layered protein-DNA regulatory…

Actively tunable photonic devices are vital for next-generation optoelectronics requiring rapid switching and high bandwidth. Although organic optoelectronic devices have found wide application, their use as optical modulators has been…

Convolutional Neural Network (CNN) recognition rates drop in the presence of noise. We demonstrate a novel method of counteracting this drop in recognition rate by adjusting the biases of the neurons in the convolutional layers according to…

Computer Vision and Pattern Recognition · Computer Science 2017-02-06 James R. Geraci , Parichay Kapoor

Atmospheric effects, such as turbulence and background thermal noise, inhibit the propagation of coherent light used in ON-OFF keying free-space optical communication. Here we present and experimentally validate a convolutional neural…

In biological cells and novel diagnostic devices biochemical receptors need to be sensitive to extremely small concentration changes of signaling molecules. The accuracy of such molecular signaling is ultimately limited by the counting…

Subcellular Processes · Quantitative Biology 2023-04-06 Aljaz Godec , Ralf Metzler

Fully test-time adaptation aims to adapt the network model based on sequential analysis of input samples during the inference stage to address the cross-domain performance degradation problem of deep neural networks. We take inspiration…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Yushun Tang , Ce Zhang , Heng Xu , Shuoshuo Chen , Jie Cheng , Luziwei Leng , Qinghai Guo , Zhihai He

A high efficiency hardware integration of neural networks benefits from realizing nonlinearity, network connectivity and learning fully in a physical substrate. Multiple systems have recently implemented some or all of these operations, yet…

Neural and Evolutionary Computing · Computer Science 2021-06-28 Louis Andreoli , Xavier Porte , Stéphane Chrétien , Maxime Jacquot , Laurent Larger , Daniel Brunner

Transport phenomena represent a very interdisciplinary topic with applications in many fields of science, such as physics, chemistry, and biology. In this context, the possibility to design a perfectly controllable experimental setup, where…

Quantum Physics · Physics 2018-06-11 Silvia Viciani , Stefano Gherardini , Manuela Lima , Marco Bellini , Filippo Caruso

The study of fluctuations in gene regulatory networks is extended to the case of Gaussian colored noise. Firstly, the solution of the corresponding Langevin equation with colored noise is expressed in terms of an Ito integral. Then, two…

Molecular Networks · Quantitative Biology 2015-05-14 Ming-Chang Huang , Jinn-Wen Wu , Yu-Pin Luo , Karen G. Petrosyan

Plant diseases serve as one of main threats to food security and crop production. It is thus valuable to exploit recent advances of artificial intelligence to assist plant disease diagnosis. One popular approach is to transform this problem…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Ruifeng Shi , Deming Zhai , Xianming Liu , Junjun Jiang , Wen Gao

In response to a concentration gradient of nutrient, E. coli bacterium modulates the rotational bias of flagellar motors which control its run-and-tumble motion, to migrate towards regions of high nutrient concentration. Presence of…

Cell Behavior · Quantitative Biology 2018-04-04 Subrata Dev , Sakuntala Chatterjee

In this work, we dive deep into the impact of additive noise in pre-training deep networks. While various methods have attempted to use additive noise inspired by the success of latent denoising diffusion models, when used in combination…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Hyesong Choi , Daeun Kim , Sungmin Cha , Kwang Moo Yi , Dongbo Min

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

Energy efficiency in computation is ultimately limited by noise, with quantum limits setting the fundamental noise floor. Analog physical neural networks hold promise for improved energy efficiency compared to digital electronic neural…

Extracellular recordings are severely contaminated by a considerable amount of noise sources, rendering the denoising process an extremely challenging task that should be tackled for efficient spike sorting. To this end, we propose an…

Neurons and Cognition · Quantitative Biology 2021-12-13 Christodoulos Kechris , Alexandros Delitzas , Vasileios Matsoukas , Panagiotis C. Petrantonakis