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The increasing complexity of transformer models in artificial intelligence expands their computational costs, memory usage, and energy consumption. Hardware acceleration tackles the ensuing challenges by designing processors and…

Hardware Architecture · Computer Science 2023-12-21 Alireza Amirshahi , Giovanni Ansaloni , David Atienza

Deep Neural Networks (DNNs) have transformed the field of machine learning and are widely deployed in many applications involving image, video, speech and natural language processing. The increasing compute demands of DNNs have been widely…

Machine Learning · Computer Science 2021-08-17 Sourjya Roy , Mustafa Ali , Anand Raghunathan

As genome sequencing is finding utility in a wide variety of domains beyond the confines of traditional medical settings, its computational pipeline faces two significant challenges. First, the creation of up to 0.5 GB of data per minute…

Sorting is a fundamental operation across numerous computational domains. Traditionally, this process involves transferring data from main memory to a processing unit for sorting, followed by writing the sorted data back to memory. This…

Hardware Architecture · Computer Science 2026-05-18 Narendra Singh Dhakad , Santosh Kumar Vishvakarma

Resistive Random Access Memory (RRAM) is an emerging device for processing-in-memory (PIM) architecture to accelerate convolutional neural network (CNN). However, due to the highly coupled crossbar structure in the RRAM array, it is…

Hardware Architecture · Computer Science 2020-10-14 Songming Yu , Yongpan Liu , Lu Zhang , Jingyu Wang , Jinshan Yue , Zhuqing Yuan , Xueqing Li , Huazhong Yang

Motivation: Read mapping is a computationally expensive process and a major bottleneck in genomics analyses. The performance of read mapping is mainly limited by the performance of three key computational steps: Index Querying, Seed…

Hardware Architecture · Computer Science 2023-10-02 Julien Eudine , Mohammed Alser , Gagandeep Singh , Can Alkan , Onur Mutlu

The two most common data-structures for genome indexing, FM-indices and hash-tables, exhibit a fundamental trade-off between memory footprint and performance. We present Ranger, a new indexing technique for nucleotide sequences that is both…

Data Structures and Algorithms · Computer Science 2023-08-09 Alon Rashelbach , Ori Rottensterich , Mark Silberstien

Recent years have seen a rapid increase in research activity in the field of DRAM-based Processing-In-Memory (PIM) accelerators, where the analog computing capability of DRAM is employed by minimally changing the inherent structure of DRAM…

Hardware Architecture · Computer Science 2023-02-16 Supreeth Mysore Shivanandamurthy , Sairam Sri Vatsavai , Ishan Thakkar , Sayed Ahmad Salehi

Compute-in-memory (CiM) is a promising approach to improving the computing speed and energy efficiency in dataintensive applications. Beyond existing CiM techniques of bitwise logic-in-memory operations and dot product operations, this…

Hardware Architecture · Computer Science 2023-01-03 Yiming Chen , Yushen Fu , Mingyen Lee , Sumitha George , Yongpan Liu , Vijaykrishnan Narayanan , Huazhong Yang , Xueqing Li

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

The research interest in specialized hardware accelerators for deep neural networks (DNN) spikes recently owing to their superior performance and efficiency. However, today's DNN accelerators primarily focus on accelerating specific…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-11 Cong Guo , Yangjie Zhou , Jingwen Leng , Yuhao Zhu , Zidong Du , Quan Chen , Chao Li , Bin Yao , Minyi Guo

Sequence alignment is a memory bound computation whose performance in modern systems is limited by the memory bandwidth bottleneck. Processing-in-memory architectures alleviate this bottleneck by providing the memory with computing…

Hardware Architecture · Computer Science 2023-03-28 Safaa Diab , Amir Nassereldine , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu , Izzat El Hajj

Genomics is the foundation of precision medicine, global food security and virus surveillance. Exact-match is one of the most essential operations widely used in almost every step of genomics such as alignment, assembly, annotation, and…

Hardware Architecture · Computer Science 2021-01-15 Lei Jiang , Farzaneh Zokaee

Neural architecture search (NAS), the study of automating the discovery of optimal deep neural network architectures for tasks in domains such as computer vision and natural language processing, has seen rapid growth in the machine learning…

Neural and Evolutionary Computing · Computer Science 2022-03-01 Daniel Cummings , Sharath Nittur Sridhar , Anthony Sarah , Maciej Szankin

We improve on GenASM, a recent algorithm for genomic sequence alignment, by significantly reducing its memory footprint and bandwidth requirement. Our algorithmic improvements reduce the memory footprint by 24$\times$ and the number of…

Hardware Architecture · Computer Science 2022-03-30 Joël Lindegger , Damla Senol Cali , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu

Artificial Neural Networks (ANN) have been popularized in many science and technological areas due to their capacity to solve many complex pattern matching problems. That is the case of Virtual Screening, a research area that studies how to…

Neural and Evolutionary Computing · Computer Science 2020-06-05 Christian F. Frasser , Carola de Benito , Vincent Canals , Miquel Roca , Pedro J. Ballester , Josep L. Rossello

Graph Neural Networks (GNNs) are becoming a promising technique in various domains due to their excellent capabilities in modeling non-Euclidean data. Although a spectrum of accelerators has been proposed to accelerate the inference of…

Hardware Architecture · Computer Science 2023-11-17 Zeyu Zhu , Fanrong Li , Gang Li , Zejian Liu , Zitao Mo , Qinghao Hu , Xiaoyao Liang , Jian Cheng

Since its invention, Generative adversarial networks (GANs) have shown outstanding results in many applications. Generative Adversarial Networks are powerful yet, resource-hungry deep-learning models. Their main difference from ordinary…

Machine Learning · Computer Science 2021-08-17 Dina Tantawy , Mohamed Zahran , Amr Wassal

Deploying Convolutional Neural Networks (CNNs) on edge platforms necessitates efficient hardware acceleration. Any unnecessary data movement in such accelerators can unacceptably degrade performance and efficiency. To address this, we…

Hardware Architecture · Computer Science 2023-11-22 Mark Horeni , Siddharth Joshi

Genetic information is increasing exponentially, doubling every 18 months. Analyzing this information within a reasonable amount of time requires parallel computing resources. While considerable research has addressed DNA analysis using…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-06-30 Suejb Memeti , Sabri Pllana