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The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

Quantitative Methods · Quantitative Biology 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Hypervariable T-cell receptors (TCR) play a key role in adaptive immunity, recognising a vast diversity of pathogen-derived antigens. High throughput sequencing of TCR repertoires (RepSeq) produces huge datasets of T-cell receptor sequences…

Detecting 3D landmarks on cone-beam computed tomography (CBCT) is crucial to assessing and quantifying the anatomical abnormalities in 3D cephalometric analysis. However, the current methods are time-consuming and suffer from large biases…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Runnan Chen , Yuexin Ma , Nenglun Chen , Lingjie Liu , Zhiming Cui , Yanhong Lin , Wenping Wang

Acute Myeloid Leukemia (AML) is one of the most aggressive types of hematological neoplasm. To support the specialists' decision about the appropriate therapy, patients with AML receive a prognostic of outcomes according to their…

Machine Learning · Computer Science 2024-05-30 Jade M. Almeida , Giovanna A. Castro , João A. Machado-Neto , Tiago A. Almeida

Accurate estimation of remaining useful life (RUL) of industrial equipment can enable advanced maintenance schedules, increase equipment availability and reduce operational costs. However, existing deep learning methods for RUL prediction…

Machine Learning · Computer Science 2020-07-21 Mohamed Ragab , Zhenghua Chen , Min Wu , Chee-Keong Kwoh , Ruqiang Yan , Xiaoli Li

Reinforcement learning (RL) is rapidly reaching and surpassing human-level control capabilities. However, state-of-the-art RL algorithms often require timesteps and reaction times significantly faster than human capabilities, which is…

Machine Learning · Computer Science 2025-07-29 Devdhar Patel , Hava Siegelmann

Acute compartment syndrome (ACS) is an orthopedic emergency, caused by elevated pressure within a muscle compartment, that leads to permanent tissue damage and eventually death. Diagnosis of ACS relies heavily on patient-reported symptoms,…

Machine Learning · Computer Science 2024-02-14 Zaina Abu Hweij , Florence Liang , Sophie Zhang

Readmissions among Medicare beneficiaries are a major problem for the US healthcare system from a perspective of both healthcare operations and patient caregiving outcomes. Our study analyzes Medicare hospital readmissions using LSTM…

Machine Learning · Computer Science 2024-10-24 Xintao Li , Sibei Liu , Dezhi Yu , Yang Zhang , Xiaoyu Liu

Sequence parallelism (SP) serves as a prevalent strategy to handle long sequences that exceed the memory limit of a single device. However, for linear sequence modeling methods like linear attention, existing SP approaches do not take…

Machine Learning · Computer Science 2025-05-19 Weigao Sun , Zhen Qin , Dong Li , Xuyang Shen , Yu Qiao , Yiran Zhong

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a rapid motor decline, leading to respiratory failure and subsequently to death. In this context, researchers have sought for models to automatically…

Machine Learning · Computer Science 2019-07-31 Telma Pereira , Sofia Pires , Marta Gromicho , Susana Pinto , Mamede de Carvalho , Sara C. Madeira

The 24-hour activity cycle (24HAC) is a new paradigm for studying activity behaviors in relation to health outcomes. This approach captures the interrelatedness of the daily time spent in physical activity (PA), sedentary behavior (SB), and…

Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a more efficient and objective alternative than manual approaches. We propose ALS longitudinal speech transformer (ALST), a neural network-based…

Objectives To develop and evaluate machine learning models to detect suspected undiagnosed nonalcoholic steatohepatitis (NASH) patients for diagnostic screening and clinical management. Methods In this retrospective observational…

This paper studies the asymptotic properties of the adaptive elastic net in ultra-high dimensional sparse linear regression models and proposes a new method called SSLS (Separate Selection from Least Squares) to improve prediction accuracy.…

Methodology · Statistics 2014-10-15 Yuehan Yang , Hu Yang

Objective: To compare different risk-based methods for optimal prediction of treatment effects. Methods: We simulated RCT data using diverse assumptions for the average treatment effect, a baseline prognostic index of risk (PI), the shape…

Landslide susceptibility prediction has always been an important and challenging content. However, there are some uncertain problems to be solved in susceptibility modeling, such as the error of landslide samples and the complex nonlinear…

Machine Learning · Computer Science 2023-10-10 Li Zhu , Lekai Liu , Changshi Yu

Machine learning systems trained on electronic health records (EHRs) increasingly guide treatment decisions, but their reliability depends on the critical assumption that patients follow the prescribed treatments recorded in EHRs. Using EHR…

Machine Learning · Computer Science 2025-04-22 Zhongyuan Liang , Arvind Suresh , Irene Y. Chen

Recent work has aimed to improve LLM generations by filtering out hallucinations, thereby improving the precision of the information in responses. Correctness of a long-form response, however, also depends on the recall of multiple pieces…

Computation and Language · Computer Science 2024-05-24 Raghuveer Thirukovalluru , Yukun Huang , Bhuwan Dhingra

Lung squamous cell carcinoma (LSCC) has a high recurrence and metastasis rate. Factors influencing recurrence and metastasis are currently unknown and there are no distinct histopathological or morphological features indicating the risks of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Weicheng Zhu , Carlos Fernandez-Granda , Narges Razavian

Large Language Models (LLMs) have demonstrated powerful reasoning capabilities through Chain-of-Thought (CoT) in various tasks, yet the inefficiency of token-by-token generation hinders real-world deployment in latency-sensitive recommender…

Information Retrieval · Computer Science 2026-05-12 Yiwen Chen , Fuwei Zhang , Zehao Chen , Deqing Wang , Hehan Li , Peizhi Xu , Hanmeng Liu , Shuanglong Li , Xin Pei , Fuzhen Zhuang , Zhao Zhang