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In recent years, significant progress has been made in the development of machine learning potentials (MLPs) for atomistic simulations with applications in many fields from chemistry to materials science. While most current MLPs are based…

Chemical Physics · Physics 2023-05-19 Tsz Wai Ko , Jonas A. Finkler , Stefan Goedecker , Jörg Behler

The energy landscape dictates pathways and outcomes in supramolecular selfassembly, yet harnessing it from the nano to the macro scales remains a major challenge. Here, we demonstrate liquid liquid phase separation (LLPS) as a powerful tool…

In this paper we first analyzed the inductive bias underlying the data scattered across complex free energy landscapes (FEL), and exploited it to train deep neural networks which yield reduced and clustered representation for the FEL. Our…

Statistical Mechanics · Physics 2021-03-19 Jun Zhang , Yao-Kun Lei , Xing Che , Zhen Zhang , Yi Isaac Yang , Yi Qin Gao

Load shapes derived from smart meter data are frequently employed to analyze daily energy consumption patterns, particularly in the context of applications like Demand Response (DR). Nevertheless, one of the most important challenges to…

Most existing random walk based network embedding methods often follow only one of two principles, homophily or structural equivalence. In real world networks, however, nodes exhibit a mixture of homophily and structural equivalence, which…

Social and Information Networks · Computer Science 2020-10-27 Chen Cui , Ning Yang , Philip S. Yu

Many problems in physics, material sciences, chemistry and biology can be abstractly formulated as a system that navigates over a complex energy landscape of high or infinite dimensions. Well-known examples include phase transitions of…

Numerical Analysis · Mathematics 2025-10-20 Weinan E , Weiqing Ren , Eric Vanden-Eijnden

The clustering methods have recently absorbed even-increasing attention in learning and vision. Deep clustering combines embedding and clustering together to obtain optimal embedding subspace for clustering, which can be more effective…

Machine Learning · Computer Science 2019-05-01 Xu Yang , Cheng Deng , Feng Zheng , Junchi Yan , Wei Liu

We explore a novel method to generate and characterize complex networks by means of their embedding on hyperbolic surfaces. Evolution through local elementary moves allows the exploration of the ensemble of networks which share common…

Statistical Mechanics · Physics 2007-09-19 T. Aste , T. Di Matteo , S. T. Hyde

A method for dimension reduction with clustering, classification, or discriminant analysis is introduced. This mixture model-based approach is based on fitting generalized hyperbolic mixtures on a reduced subspace within the paradigm of…

Methodology · Statistics 2017-10-09 Katherine Morris , Paul D. McNicholas

Convolutional neural networks (CNNs) have become increasingly difficult to deploy in resource-constrained environments due to their large memory and computational requirements. Although low-rank compression methods can reduce this burden,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Sisipho Hamlomo , Marcellin Atemkeng , Habte Tadesse Likassa , Blaise Ravelo , Thierry Bouwmans , Sébastien Lalléchère , Antoine Vacavant , Ding-Geng Chen

The classical approach to protein folding inspired by statistical mechanics avoids the high dimensional structure of the conformation space by using effective coordinates. Here we introduce a network approach to capture the statistical…

Biomolecules · Quantitative Biology 2007-05-23 Erzsebet Ravasz , S. Gnanakaran , Zoltan Toroczkai

Macromolecular and biomolecular folding landscapes typically contain high free energy barriers that impede efficient sampling of configurational space by standard molecular dynamics simulation. Biased sampling can artificially drive the…

Biological Physics · Physics 2018-11-01 Wei Chen , Andrew L Ferguson

Network embedding, which aims to learn low-dimensional representations of nodes, has been used for various graph related tasks including visualization, link prediction and node classification. Most existing embedding methods rely solely on…

Social and Information Networks · Computer Science 2019-08-22 Palash Goyal , Homa Hosseinmardi , Emilio Ferrara , Aram Galstyan

Recent studies increasingly adopt simulation-based machine learning (ML) models to analyze critical infrastructure system resilience. For realistic applications, these ML models consider the component-level characteristics that influence…

Machine Learning · Computer Science 2022-05-09 Srijith Balakrishnan , Beatrice Cassottana , Arun Verma

Clustering algorithms remain valuable tools for grouping and summarizing the most important aspects of data. Example areas where this is the case include image segmentation, dimension reduction, signals analysis, model order reduction,…

Numerical Analysis · Mathematics 2024-12-24 Guy B. Oldaker , Maria Emelianenko

Sentence embedding methods offer a powerful approach for working with short textual constructs or sequences of words. By representing sentences as dense numerical vectors, many natural language processing (NLP) applications have improved…

Computation and Language · Computer Science 2021-10-05 Yuan An , Alexander Kalinowski , Jane Greenberg

Learning energy-based model (EBM) requires MCMC sampling of the learned model as an inner loop of the learning algorithm. However, MCMC sampling of EBMs in high-dimensional data space is generally not mixing, because the energy function,…

Machine Learning · Statistics 2022-03-17 Erik Nijkamp , Ruiqi Gao , Pavel Sountsov , Srinivas Vasudevan , Bo Pang , Song-Chun Zhu , Ying Nian Wu

A common approach for compressing NLP networks is to encode the embedding layer as a matrix $A\in\mathbb{R}^{n\times d}$, compute its rank-$j$ approximation $A_j$ via SVD, and then factor $A_j$ into a pair of matrices that correspond to…

Machine Learning · Computer Science 2020-10-12 Alaa Maalouf , Harry Lang , Daniela Rus , Dan Feldman

A variety of enhanced sampling methods predict multidimensional free energy landscapes associated with biological and other molecular processes as a function of a few selected collective variables (CVs). The accuracy of these methods is…

Computational Physics · Physics 2024-04-09 Lukas Müllender , Andrea Rizzi , Michele Parrinello , Paolo Carloni , Davide Mandelli

Given i.i.d. sample from a stratified mixture of immersed manifolds of different dimensions, we study the minimax estimation of the underlying stratified structure. We provide a constructive algorithm allowing to estimate each mixture…

Statistics Theory · Mathematics 2024-05-31 Eddie Aamari , Clément Berenfeld