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Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…
Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…
Accurate classification of brain tumors from MRI scans is critical for effective treatment planning. This study presents a Hybrid Quantum Convolutional Neural Network (HQCNN) that integrates quantum feature-encoding circuits with depth-wise…
Developing computational tools for integrative analysis across multiple types of omics data has been of immense importance in cancer molecular biology and precision medicine research. While recent advancements have yielded integrative…
In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…
This article presents a convolutional neural network for the automatic segmentation of brain tumors in multimodal 3D MR images based on a U-net architecture.We evaluate the use of a densely connected convolutional network encoder (DenseNet)…
Recent advances in neuroscience data acquisition allow for the simultaneous recording of large populations of neurons across multiple brain areas while subjects perform complex cognitive tasks. Interpreting these data requires us to index…
This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…
Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…
The development and use of large-scale quantum computers relies on integrating quantum error-correcting (QEC) schemes into the quantum computing pipeline. A fundamental part of the QEC protocol is the decoding of the syndrome to identify a…
This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…
Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…
We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…
Neural networks have become the standard technique for medical diagnostics, especially in cancer detection and classification. This work evaluates the performance of Vision Transformers architectures, including Swin Transformer and MaxViT,…
Brain tumor segmentation is essential for the diagnosis and prognosis of patients with gliomas. The brain tumor segmentation challenge has continued to provide a great source of data to develop automatic algorithms to perform the task. This…
The characterization of Tumor MicroEnvironment (TME) is challenging due to its complexity and heterogeneity. Relatively consistent TME characteristics embedded within highly specific tissue features, render them difficult to predict. The…
Due to the high heterogeneity and clinical characteristics of cancer, there are significant differences in multi-omic data and clinical characteristics among different cancer subtypes. Therefore, accurate classification of cancer subtypes…
Brain tumor is deliberated as one of the severe health complications which lead to decrease in life expectancy of the individuals and is also considered as a prominent cause of mortality worldwide. Therefore, timely detection and prediction…
We propose a methodology for the identification of transcription factors involved in the deregulation of genes in tumoral cells. This strategy is based on the inference of a reference gene regulatory network that connects transcription…
Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…