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Background: With the ever-increasing amount of medical imaging data, the demand for algorithms to assist clinicians has amplified. Unsupervised anomaly detection (UAD) models promise to aid in the crucial first step of disease detection.…

Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common performance measures may be too general or too specific. For binary classifiers, diagnostic tests or prognosis at a timepoint,…

The adoption of diagnosis and prognostic algorithms in healthcare has led to concerns about the perpetuation of bias against disadvantaged groups of individuals. Deep learning methods to detect and mitigate bias have revolved around…

Anomaly detection is a dynamic field, in which the evaluation of models plays a critical role in understanding their effectiveness. The selection and interpretation of the evaluation metrics are pivotal, particularly in scenarios with…

Machine Learning · Computer Science 2024-09-25 Minjae Ok , Simon Klüttermann , Emmanuel Müller

Despite numerous studies of deep autoencoders (AEs) for unsupervised anomaly detection, AEs still lack a way to express uncertainty in their predictions, crucial for ensuring safe and trustworthy machine learning systems in high-stake…

Machine Learning · Computer Science 2022-02-28 Bang Xiang Yong , Alexandra Brintrup

Quality assessment algorithms can be used to estimate the utility of a biometric sample for the purpose of biometric recognition. "Error versus Discard Characteristic" (EDC) plots, and "partial Area Under Curve" (pAUC) values of curves…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Torsten Schlett , Christian Rathgeb , Juan Tapia , Christoph Busch

In high-stakes risk prediction, quantifying uncertainty through interval-valued predictions is essential for reliable decision-making. However, standard evaluation tools like the receiver operating characteristic (ROC) curve and the area…

Machine Learning · Computer Science 2026-02-05 Yuqi Li , Matthew M. Engelhard

When determining which machine learning model best performs some high impact risk assessment task, practitioners commonly use the Area under the Curve (AUC) to defend and validate their model choices. In this paper, we argue that the…

Computers and Society · Computer Science 2023-05-30 Kweku Kwegyir-Aggrey , Marissa Gerchick , Malika Mohan , Aaron Horowitz , Suresh Venkatasubramanian

We study fairness in the context of classification where the performance is measured by the area under the curve (AUC) of the receiver operating characteristic. AUC is commonly used to measure the performance of prediction models. The same…

Machine Learning · Computer Science 2022-08-25 Hortense Fong , Vineet Kumar , Anay Mehrotra , Nisheeth K. Vishnoi

The Area Under the ROC Curve (AUC) is a widely used performance metric for binary classifiers. However, as a global ranking statistic, the AUC aggregates model behavior over the entire dataset, masking localized weaknesses in specific…

Applications · Statistics 2025-08-12 Agus Sudjianto , Alice J. Liu

The Area Under the ROC Curve (AUC) is a widely employed metric in long-tailed classification scenarios. Nevertheless, most existing methods primarily assume that training and testing examples are drawn i.i.d. from the same distribution,…

Machine Learning · Computer Science 2023-11-07 Siran Dai , Qianqian Xu , Zhiyong Yang , Xiaochun Cao , Qingming Huang

The use of machine learning models in consequential decision making often exacerbates societal inequity, in particular yielding disparate impact on members of marginalized groups defined by race and gender. The area under the ROC curve…

Machine Learning · Computer Science 2022-11-30 Zhenhuan Yang , Yan Lok Ko , Kush R. Varshney , Yiming Ying

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

Unsupervised recalibration (URC) is a general way to improve the accuracy of an already trained probabilistic classification or regression model upon encountering new data while deployed in the field. URC does not require any ground truth…

Machine Learning · Statistics 2020-10-20 Albert Ziegler , Paweł Czyż

The predictive quality of machine learning models is typically measured in terms of their (approximate) expected prediction error or the so-called Area Under the Curve (AUC) for a particular data distribution. However, when the models are…

Machine Learning · Computer Science 2018-02-08 Hiva Ghanbari , Katya Scheinberg

Uncertainty quantification (UQ) in deep learning regression is of wide interest, as it supports critical applications including sequential decision making and risk-sensitive tasks. In heteroskedastic regression, where the uncertainty of the…

Machine Learning · Computer Science 2026-03-03 Mikkel Jordahn , Jonas Vestergaard Jensen , James Harrison , Michael Riis Andersen , Mikkel N. Schmidt

Deploying deep learning (DL) models in medical applications relies on predictive performance and other critical factors, such as conveying trustworthy predictive uncertainty. Uncertainty estimation (UE) methods provide potential solutions…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Kudaibergen Abutalip , Numan Saeed , Ikboljon Sobirov , Vincent Andrearczyk , Adrien Depeursinge , Mohammad Yaqub

Despite strong zero-shot performance, SAM is unreliable under domain shift due to Mask-level Confidence Confusion (MCC), where a single IoU-based mask score fails to reflect pixel-wise reliability near boundaries. Motivated by the contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Hongyou Zhou , Marc Toussaint , Ling Shao , Zihan Ye

In this work, we introduce Entropy Area Score (EAS), a simple yet effective metric to quantify uncertainty in the answer generation process of reasoning large language models (LLMs). EAS requires neither external models nor repeated…

Artificial Intelligence · Computer Science 2025-08-29 Yongfu Zhu , Lin Sun , Guangxiang Zhao , Weihong Lin , Xiangzheng Zhang

Medical anomaly detection (AD) is crucial in pathological identification and localization. Current methods typically rely on uncertainty estimation in deep ensembles to detect anomalies, assuming that ensemble learners should agree on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Yi Gu , Yi Lin , Kwang-Ting Cheng , Hao Chen
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