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Liquid liquid phase separation (LLPS) mediated by pi-cation bonds between tyrosine and arginine residues are of biological importance. To understand the interactions between proteins in the condensed phase in close analogy to complex…

Biological Physics · Physics 2020-08-19 Aditya N. Singh , Arun Yethiraj

The dynamics of phase separation in multi-component bilayer fluid vesicles is investigated by means of large-scale dissipative particle dynamics. The model explicitly accounts for solvent particles, thereby allowing for the very first…

Soft Condensed Matter · Physics 2009-11-10 Mohamed Laradji , P. B. Sunil Kumar

The complexity of biomolecular interactions necessitates advanced methodologies to accurately capture their behavior in solution. In this work, we focus on monoclonal antibodies and adopt a multi-scale coarse-graining strategy for their…

We used x-ray photon correlation spectroscopy to study the dynamics in the lamellar phase of a platelet suspension as a function of the particle concentration. We measured the collective diffusion coefficient along the director of the…

Soft Condensed Matter · Physics 2015-04-07 Doru Constantin , Patrick Davidson , Éric Freyssingeas , Anders Madsen

We perform systematic molecular dynamics simulations of water confined between two nanoscale plates at T=300 K. We investigate the effect of pressure (-0.15 GPa <= P <= 0.2 GPa) and plate separation (0.4 nm <= d <= 1.6 nm) on the phase…

Chemical Physics · Physics 2016-09-08 Nicolas Giovambattista , Peter J. Rossky , Pablo G. Debenedetti

A general quantitative measure of the tendency towards phase separation is introduced for systems exhibiting phase transitions or crossovers controlled by charge carrier concentration. This measure is devised for the situations when the…

Strongly Correlated Electrons · Physics 2011-05-02 Boris V. Fine , Takeshi Egami

We develop a lattice-based Monte Carlo simulation method for charged mixtures capable of treating dielectric heterogeneities. Using this method, we study oil-water mixtures containing an antagonistic salt, with hydrophilic cations and…

Soft Condensed Matter · Physics 2017-11-29 Nikos Tasios , Sela Samin , René van Roij , Marjolein Dijkstra

We find that a system of particles interacting through a simple isotropic potential with a softened core is able to exhibit a rich phase behavior including: a liquid-liquid phase transition in the supercooled phase, as has been suggested…

Soft Condensed Matter · Physics 2009-10-31 G. Malescio , G. Pellicane

Liquid-liquid phase separation is emerging as a crucial phenomenon in several fundamental cell processes. A range of eukaryotic systems exhibit liquid condensates. However, their function in bacteria, which in general lack membrane-bound…

When a fluid with a bulk liquid-vapor critical point is placed inside a static external field with spatial periodic oscillations in one direction, the bulk critical point splits into two new critical points and a triple point. This…

Soft Condensed Matter · Physics 2015-05-27 Richard Vink , Tim Neuhaus , Hartmut Loewen

In this study we use non-equilibrium thermodynamics to systematically derive a phase-field model of a polyelectrolyte gel coupled to a hydrodynamic model for a salt solution surrounding the gel. The governing equations for the gel account…

Soft Condensed Matter · Physics 2022-03-02 Giulia L. Celora , Matthew G. Hennessy , Andreas Münch , Barbara Wagner , Sarah L. Waters

We study the phase behavior of colloidal suspensions the solvents of which are considered to be binary liquid mixtures undergoing phase segregation. We focus on the thermodynamic region close to the critical point of the accompanying…

Soft Condensed Matter · Physics 2015-06-03 T. F. Mohry , A. Maciołek , S. Dietrich

We investigate liquid-liquid phase separation (LLPS) and interfacial properties of two LLPS modes: associative (ALLPS) and segregative (SLLPS). Analytical expressions for the critical point (CP) and binodal boundaries are derived and show…

Soft Condensed Matter · Physics 2025-10-30 Remco Tuinier , Alvaro Gonzalez Garcia

Biomolecular self-assembly spatially segregates proteins with a limited number of binding sites (valence) into condensates that coexist with a dilute phase. We develop a many-body lattice model for a three-component system of proteins with…

Soft Condensed Matter · Physics 2022-01-13 Saroj Kumar Nandi , Daniel Österle , Meta Heidenreich , Emmanuel D. Levy , Samuel A. Safran

We present a perspective on recent observations of the photoinduced phase separation of halides in multi-component lead-halide perovskites. The spontaneous phase separation of an initial homogeneous solid solution under steady-state…

Applied Physics · Physics 2020-07-15 David T. Limmer , Naomi S. Ginsberg

The connection between domain relaxations at individual scales and the collective heterogeneous response in non-equilibrium systems is a topic of profound interest in recent times. In a model sys- tem of constantly driven oppositely charged…

Soft Condensed Matter · Physics 2016-12-16 Suman Dutta

An electric-field-induced phase transition and pattern formation in a binary dielectric fluid layer are studied using a coarse-grained free energy functional. The electrostatic part of the free energy is a nonlinear functional of the…

Soft Condensed Matter · Physics 2007-05-23 M. D. Johnson , X. Duan , Brett Riley , Aniket Bhattacharya , Weili Luo

Multi-component membranes such as ternary mixtures of lipids and cholesterol can exhibit coexistence regions between two liquid phases. When such membranes adhere to a corrugated substrate, the phase separation process strongly depends on…

Soft Condensed Matter · Physics 2009-11-13 Bartosz Rozycki , Thomas R. Weikl , Reinhard Lipowsky

Dynamic processes in dispersions of charged spherical particles are of importance both in fundamental science, and in technical and bio-medical applications. There exists a large variety of charged-particles systems, ranging from…

Soft Condensed Matter · Physics 2013-11-25 G. Nägele , M. Heinen , A. J. Banchio , C. Contreras-Aburto

We study the phase behavior of a system of charged colloidal particles that are electrostatically bound to an almost flat interface between two fluids. We show that, despite the fact that our experimental system consists of only $10^{3}$ -…

Soft Condensed Matter · Physics 2017-02-09 Colm P. Kelleher , Rodrigo E. Guerra , Andrew D. Hollingsworth , Paul M. Chaikin