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High-dimensional tensor models are notoriously computationally expensive to train. We present a meta-learning algorithm, MMT, that can significantly speed up the process for spatial tensor models. MMT leverages the property that spatial…

Machine Learning · Computer Science 2018-03-01 Stephan Zheng , Rose Yu , Yisong Yue

Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack of standards have constrained computational methods in…

Recently, Transformer networks have demonstrated outstanding performance in the field of image restoration due to the global receptive field and adaptability to input. However, the quadratic computational complexity of Softmax-attention…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Zhi Jin , Yuwei Qiu , Kaihao Zhang , Hongdong Li , Wenhan Luo

The rapid development of spatial transcriptomics (ST) technologies is revolutionizing our understanding of the spatial organization of biological tissues. Current ST methods, categorized into next-generation sequencing-based (seq-based) and…

Machine Learning · Computer Science 2024-07-19 Xiaoyu Li , Fangfang Zhu , Wenwen Min

The rapid advancement of spatial transcriptomics (ST), i.e., spatial gene expressions, has made it possible to measure gene expression within original tissue, enabling us to discover molecular mechanisms. However, current ST platforms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xiaofei Wang , Stephen Price , Chao Li

Survival prediction is a complicated ordinal regression task that aims to predict the ranking risk of death, which generally benefits from the integration of histology and genomic data. Despite the progress in joint learning from pathology…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Yingxue Xu , Hao Chen

Background. A large number of algorithms is being developed to reconstruct evolutionary models of individual tumours from genome sequencing data. Most methods can analyze multiple samples collected either through bulk multi-region…

Genomics · Quantitative Biology 2019-03-26 Daniele Ramazzotti , Alex Graudenzi , Luca De Sano , Marco Antoniotti , Giulio Caravagna

Glioblastoma multiforme (GBM) is an aggressive form of human brain cancer that is under active study in the field of cancer biology. Its rapid progression and the relative time cost of obtaining molecular data make other readily-available…

Applications · Statistics 2019-11-14 Lorin Crawford , Anthea Monod , Andrew X. Chen , Sayan Mukherjee , Raúl Rabadán

Spatial transcriptomics (ST) enables mapping gene expression with spatial context but is severely affected by high sparsity and technical noise, which conceals true biological signals and hinders downstream analyses. To address these…

Machine Learning · Computer Science 2026-03-10 Sayeem Bin Zaman , Fahim Hafiz , Riasat Azim

Medical imaging is a critical initial tool used by clinicians to determine a patient's cancer diagnosis, allowing for faster intervention and more reliable patient prognosis. At subsequent stages of patient diagnosis, genetic information is…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Rahul Mehta

Radio map, or pathloss map prediction, is a crucial method for wireless network modeling and management. By leveraging deep learning to construct pathloss patterns from geographical maps, an accurate digital replica of the transmission…

Signal Processing · Electrical Eng. & Systems 2025-01-14 Yuxuan Li , Cheng Zhang , Wen Wang , Yongming Huang

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

Background and objective: High-resolution radiographic images play a pivotal role in the early diagnosis and treatment of skeletal muscle-related diseases. It is promising to enhance image quality by introducing single-image…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Yongsong Huang , Tomo Miyazaki , Xiaofeng Liu , Kaiyuan Jiang , Zhengmi Tang , Shinichiro Omachi

In order to understand the complexities of cellular biology, researchers are interested in two important metrics: the genetic expression information of cells and their spatial coordinates within a tissue sample. However, state-of-the art…

Machine Learning · Computer Science 2023-11-02 J. Ding , S. N. Zaman , P. Y. Chen , D. Wang

In this paper we propose a method for transfer learning of endoscopic images. For transferring between features obtained from images taken by different (old and new) endoscopes, we extend the Max-Margin Domain Transfer (MMDT) proposed by…

Computer Vision and Pattern Recognition · Computer Science 2016-08-25 Shoji Sonoyama , Toru Tamaki , Tsubasa Hirakawa , Bisser Raytchev , Kazufumi Kaneda , Tetsushi Koide , Shigeto Yoshida , Hiroshi Mieno , Shinji Tanaka

The classification of gigapixel histopathology images with deep multiple instance learning models has become a critical task in digital pathology and precision medicine. In this work, we propose a Transformer-based multiple instance…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Josef Cersovsky , Sadegh Mohammadi , Dagmar Kainmueller , Johannes Hoehne

Forecasting high-resolution land subsidence is a critical yet challenging task due to its complex, non-linear dynamics. While standard architectures like ConvLSTM often fail to model long-range dependencies, we argue that a more fundamental…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wendong Yao , Binhua Huang , Soumyabrata Dev

Spatial transcriptomics (ST) has revolutionised transcriptomics analysis by preserving tissue architecture, allowing researchers to study gene expression in its native spatial context. However, despite its potential, ST still faces…

Quantitative Methods · Quantitative Biology 2025-05-19 Anthony Baptista , Rosamond Nuamah , Ciro Chiappini , Anita Grigoriadis

Robotic ultrasound (US) systems have shown great potential to make US examinations easier and more accurate. Recently, various machine learning techniques have been proposed to realize automatic US image interpretation for robotic US…

Robotics · Computer Science 2023-05-17 Keyu Li , Xinyu Mao , Chengwei Ye , Ang Li , Yangxin Xu , Max Q. -H. Meng

Emerging research has highlighted that artificial intelligence-based multimodal fusion of digital pathology and transcriptomic features can improve cancer diagnosis (grading/subtyping) and prognosis (survival risk) prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Samiran Dey , Christopher R. S. Banerji , Partha Basuchowdhuri , Sanjoy K. Saha , Deepak Parashar , Tapabrata Chakraborti
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