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We present a highly efficient and accurate hybrid stochastic simulation algorithm (HSSA) for the purpose of simulating a subset of biochemical reactions of large gene regulatory networks (GRN). The algorithm relies on the separability of a…

Molecular Networks · Quantitative Biology 2020-09-29 Jaroslav Albert

The conductor-like polarization model (C-PCM) with switching/Gaussian smooth discretization is a widely used implicit solvation model in chemical simulations. However, its application in quantum mechanical calculations of large-scale…

Chemical Physics · Physics 2015-07-03 Fang Liu , Nathan Luehr , Heather J. Kulik , Todd J. Martínez

In this paper, we will demonstrate how to use a nonlinear polyhedral constrained optimization solver called the Polyhedral Active Set Algorithm (PASA) for solving a general singular control problem. We present methods of discretizing a…

Optimization and Control · Mathematics 2020-10-15 Summer Atkins , Mahya Aghaee , Maia Martcheva , William Hager

A tridiagonal matrix algorithm (TDMA), Pipelined-TDMA, is developed for multi-GPU systems to resolve the scalability bottlenecks caused by the sequential structure of conventional divide-and-conquer TDMA. The proposed method pipelines…

Computational Physics · Physics 2025-09-05 Seungchan Kim , Jihoo Kim , Sanghyun Ha , Donghyun You

The paper presents the aspect of use of modern graphics accelerators supporting CUDA technology for high-performance computing in the field of linear algebra. Fully programmable graphic cards have been available for several years for both…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-06-27 Lukasz Swierczewski

Recent developments for mathematical modeling and numerical simulation of biomolecular systems raise new demands for qualified, stable, and efficient surface meshing, especially in implicit-solvent modeling. In our former work, we have…

Numerical Analysis · Mathematics 2016-11-11 Tiantian Liu , Minxin Chen , Benzhuo Lu

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

Algorithms that use derivatives of governing equations have accelerated rigid robot simulations and improved their accuracy, enabling the modeling of complex, real-world capabilities. However, extending these methods to soft and hybrid…

Robotics · Computer Science 2024-11-08 Anup Teejo Mathew , Frederic Boyer , Vincent Lebastard , Federico Renda

Neural Processes (NPs) are a rapidly evolving class of models designed to directly model the posterior predictive distribution of stochastic processes. While early architectures were developed primarily as a scalable alternative to Gaussian…

Quantifying how hard it is to build a molecular graph matters for biosignature detection, chemical complexity, and cheminformatics. We present an exact, scalable algorithm to compute the molecular assembly index (MA) which prioritizes the…

Data Structures and Algorithms · Computer Science 2025-08-19 Ian Seet , Keith Y. Patarroyo , Gage Siebert , Sara I. Walker , Leroy Cronin

Deep neural representations of 3D shapes as implicit functions have been shown to produce high fidelity models surpassing the resolution-memory trade-off faced by the explicit representations using meshes and point clouds. However, most…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Rahul Venkatesh , Tejan Karmali , Sarthak Sharma , Aurobrata Ghosh , R. Venkatesh Babu , László A. Jeni , Maneesh Singh

We explore different ways to simplify the evaluation of the smooth overlap of atomic positions (SOAP) many-body atomic descriptor [Bart\'{o}k et al., Phys. Rev. B 87, 184115 (2013)]. Our aim is to improve the computational efficiency of…

Computational Physics · Physics 2019-09-16 Miguel A. Caro

Surgical reconstruction of dynamic tissues from endoscopic videos is a crucial technology in robot-assisted surgery. The development of Neural Radiance Fields (NeRFs) has greatly advanced deformable tissue reconstruction, achieving…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Wenfeng Huang , Xiangyun Liao , Yinling Qian , Hao Liu , Yongming Yang , Wenjing Jia , Qiong Wang

This study presents a reconstruction of the Gaussian Beam Tracing solution using CUDA, with a particular focus on the utilisation of GPU acceleration as a means of overcoming the performance limitations of traditional CPU algorithms in…

Performance · Computer Science 2025-01-24 Zhang Sheng , Lishu Duan , Hanbo Jiang

We investigate the solvent-accessible area method by means of Metropolis simulations of the brain peptide Met-Enkephalin at 300$ K$. For the energy function ECEPP/2 nine atomic solvation parameter (ASP) sets are studied. The simulations are…

Statistical Mechanics · Physics 2009-11-10 Bernd A. Berg , Hsiao-Ping Hsu

A new flow solver scalable on multiple Graphics Processing Units (GPUs) for direct numerical simulation of wall-bounded incompressible flow is presented. This solver utilizes a previously reported work (J. Comp. Physics, vol. 352 (2018),…

Computational Physics · Physics 2018-12-05 Sanghyun Ha , Junshin Park , Donghyun You

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

This paper presents SAGA (Segment Any 3D GAussians), a highly efficient 3D promptable segmentation method based on 3D Gaussian Splatting (3D-GS). Given 2D visual prompts as input, SAGA can segment the corresponding 3D target represented by…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Jiazhong Cen , Jiemin Fang , Chen Yang , Lingxi Xie , Xiaopeng Zhang , Wei Shen , Qi Tian

We present a new adaptive parallel algorithm for the challenging problem of multi-dimensional numerical integration on massively parallel architectures. Adaptive algorithms have demonstrated the best performance, but efficient many-core…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-24 Ioannis Sakiotis , Kamesh Arumugam , Marc Paterno , Desh Ranjan , Balša Terzić , Mohammad Zubair

The discrete dipole approximation (DDA) is a widely used and versatile numerical method for solving electromagnetic scattering by arbitrarily shaped objects. Despite its popularity, quantitative comparisons between independent…

Computational Physics · Physics 2026-05-13 Clément Argentin , Patrick C. Chaumet , Michel Gross , Maxim A. Yurkin