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The advent of molecular biology has led to the identification of definitive causative factors for a number of diseases, most of which are monogenic. Causes for most common diseases across the population, however, seem elusive and cannot be…

Quantitative Methods · Quantitative Biology 2013-10-03 Sepehr Ehsani

Deep Learning models have shown success in a large variety of tasks by extracting correlation patterns from high-dimensional data but still struggle when generalizing out of their initial distribution. As causal engines aim to learn…

Machine Learning · Computer Science 2024-01-02 Gaël Gendron , Michael Witbrock , Gillian Dobbie

To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision…

Quantitative Methods · Quantitative Biology 2025-04-09 Tom Michoel , Jitao David Zhang

With the increasing availability and size of multi-omics datasets, investigating the casual relationships between molecular phenotypes has become an important aspect of exploring underlying biology and genetics. This paper aims to introduce…

Molecular Networks · Quantitative Biology 2022-01-31 Jack Kelly , Carlo Berzuini , Bernard Keavney , Maciej Tomaszewski , Hui Guo

Causality is omnipresent in scientists' verbalisations of their understanding, even though we have no formal consensual scientific definition for it. In Automata Networks, it suffices to say that automata "influence" one another to…

Other Computer Science · Computer Science 2016-10-28 Mathilde Noual

Emergence and causality are two fundamental concepts for understanding complex systems. They are interconnected. On one hand, emergence refers to the phenomenon where macroscopic properties cannot be solely attributed to the cause of…

Physics and Society · Physics 2024-02-27 Bing Yuan , Zhang Jiang , Aobo Lyu , Jiayun Wu , Zhipeng Wang , Mingzhe Yang , Kaiwei Liu , Muyun Mou , Peng Cui

Causality is a fundamental part of the scientific endeavour to understand the world. Unfortunately, causality is still taboo in much of psychology and social science. Motivated by a growing number of recommendations for the importance of…

Methodology · Statistics 2022-06-27 Matthew J. Vowels

Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex…

Quantitative Methods · Quantitative Biology 2018-05-07 Alex White , Matthieu Vignes

Determining and measuring cause-effect relationships is fundamental to most scientific studies of natural phenomena. The notion of causation is distinctly different from correlation which only looks at association of trends or patterns in…

Methodology · Statistics 2019-10-22 Aditi Kathpalia , Nithin Nagaraj

Concurrent systems identify systems, either software, hardware or even biological systems, that are characterized by sets of independent actions that can be executed in any order or simultaneously. Computer scientists resort to a causal…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-03-07 Silvia Crafa , Federica Russo

Causality has become a fundamental approach for explaining the relationships between events, phenomena, and outcomes in various fields of study. It has invaded various fields and applications, such as medicine, healthcare, economics,…

Artificial Intelligence · Computer Science 2024-03-19 Abraham Itzhak Weinberg , Cristiano Premebida , Diego Resende Faria

Causal reasoning is a crucial part of science and human intelligence. In order to discover causal relationships from data, we need structure discovery methods. We provide a review of background theory and a survey of methods for structure…

Machine Learning · Computer Science 2021-03-05 Matthew J. Vowels , Necati Cihan Camgoz , Richard Bowden

Recommender systems are important and powerful tools for various personalized services. Traditionally, these systems use data mining and machine learning techniques to make recommendations based on correlations found in the data. However,…

Information Retrieval · Computer Science 2023-01-11 Shuyuan Xu , Jianchao Ji , Yunqi Li , Yingqiang Ge , Juntao Tan , Yongfeng Zhang

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

Causal reasoning is essential to science, yet quantum theory challenges it. Quantum correlations violating Bell inequalities defy satisfactory causal explanations within the framework of classical causal models. What is more, a theory…

Quantum Physics · Physics 2021-03-05 Jonathan Barrett , Robin Lorenz , Ognyan Oreshkov

We formally characterize a set of causality-based properties of metabolic networks. This set of properties aims at making precise several notions on the production of metabolites, which are familiar in the biologists' terminology. From a…

Computational Engineering, Finance, and Science · Computer Science 2010-02-23 Chiara Bodei , Andrea Bracciali , Davide Chiarugi , Roberta Gori

Complex systems have interested researchers across a broad range of fields for many years and as computing has become more accesible and feasible, it is now possible to simulate aspects of these systems. A major point of research is how…

Multiagent Systems · Computer Science 2019-01-16 George Hassan-Coring

Recent years have witnessed the rapid growth of machine learning in a wide range of fields such as image recognition, text classification, credit scoring prediction, recommendation system, etc. In spite of their great performance in…

Machine Learning · Computer Science 2021-09-20 Guandong Xu , Tri Dung Duong , Qian Li , Shaowu Liu , Xianzhi Wang

Causal reasoning is the main learning and explanation tool used by humans. AI systems should possess causal reasoning capabilities to be deployed in the real world with trust and reliability. Introducing the ideas of causality to machine…

Machine Learning · Computer Science 2021-06-11 Abbavaram Gowtham Reddy

This paper analyzes the notion of causality in a conceptual model, mainly as applied in software engineering. Conceptual system modeling can be considered a three-level process that begins with building a static structural description to…

Software Engineering · Computer Science 2020-05-07 Sabah Al-Fedaghi
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