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The fundamental biological processes of development of tissues and organs in multicellular organisms is governed by various signaling molecules, which are called morphogens. It is known that spatial and temporal variations in concentration…
Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…
Molecular generation plays an important role in drug discovery and materials science, especially in data-scarce scenarios where traditional generative models often struggle to achieve satisfactory conditional generalization. To address this…
Graph generation is a crucial task in many fields, including network science and bioinformatics, as it enables the creation of synthetic graphs that mimic the properties of real-world networks for various applications. Graph Generative…
Deep learning algorithms for connectomics rely upon localized classification, rather than overall morphology. This leads to a high incidence of erroneously merged objects. Humans, by contrast, can easily detect such errors by acquiring…
Molecule generation is a challenging open problem in cheminformatics. Currently, deep generative approaches addressing the challenge belong to two broad categories, differing in how molecules are represented. One approach encodes molecular…
Simulating urban morphology with location attributes is a challenging task in urban science. Recent studies have shown that Generative Adversarial Networks (GANs) have the potential to shed light on this task. However, existing GAN-based…
Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…
We describe a layer-by-layer algorithm for training deep convolutional networks, where each step involves gradient updates for a two layer network followed by a simple clustering algorithm. Our algorithm stems from a deep generative model…
Graph foundation models represent a transformative paradigm for learning transferable representations across diverse graph domains. Recent methods leverage large language models to unify graph and text modalities into a shared…
Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cell topology enables realistic simulations of complex tissue…
Identity-preserving face synthesis aims to generate synthetic face images of virtual subjects that can substitute real-world data for training face recognition models. While prior arts strive to create images with consistent identities and…
It is often the case that the performance of a neural network can be improved by adding layers. In real-world practices, we always train dozens of neural network architectures in parallel which is a wasteful process. We explored $CompNet$,…
Drug discovery is a complex, resource-intensive process requiring significant time and cost to bring new medicines to patients. Many generative models aim to accelerate drug discovery, but few produce synthetically accessible molecules.…
Synthesizing geometrical shapes from human brain activities is an interesting and meaningful but very challenging topic. Recently, the advancements of deep generative models like Generative Adversarial Networks (GANs) have supported the…
Sound morphing is the process of gradually and smoothly transforming one sound into another to generate novel and perceptually hybrid sounds that simultaneously resemble both. Recently, diffusion-based text-to-audio models have produced…
Generating cognitive-aligned layered SVGs remains challenging due to existing methods' tendencies toward either oversimplified single-layer outputs or optimization-induced shape redundancies. We propose LayerTracer, a diffusion transformer…
Neural Cellular Automata (NCA) have shown a remarkable ability to learn the required rules to "grow" images, classify morphologies, segment images, as well as to do general computation such as path-finding. We believe the inductive prior…
In common real-world robotic operations, action and state spaces can be vast and sometimes unknown, and observations are often relatively sparse. How do we learn the full topology of action and state spaces when given only few and sparse…
Traditional gradient boosting algorithms employ static tree structures with fixed splitting criteria that remain unchanged throughout training, limiting their ability to adapt to evolving gradient distributions and problem-specific…