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The process of morphogenesis is an evolution of the shape of an organism together with the differentiation of its parts. This process encompasses numerous biological processes ranging from embryogenesis to regeneration following crisis such…

Other Quantitative Biology · Quantitative Biology 2019-09-23 N. Bessonov , O. Butuzova , A. Minarsky , R. Penner , C. Soule , A. Tosenberger , N. Morozova

Direct prediction of material properties from microstructures through statistical models has shown to be a potential approach to accelerating computational material design with large design spaces. However, statistical modeling of highly…

Computational Physics · Physics 2017-12-12 Ruijin Cang , Hechao Li , Hope Yao , Yang Jiao , Yi Ren

Deep Neural Networks (DNNs) are generated by sequentially performing linear and non-linear processes. Using a combination of linear and non-linear procedures is critical for generating a sufficiently deep feature space. The majority of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-29 Yufei Hu , Nacim Belkhir , Jesus Angulo , Angela Yao , Gianni Franchi

Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

Deep learning on graphs has become a popular research topic with many applications. However, past work has concentrated on learning graph embedding tasks, which is in contrast with advances in generative models for images and text. Is it…

Machine Learning · Computer Science 2018-02-13 Martin Simonovsky , Nikos Komodakis

We propose a manifold matching approach to generative models which includes a distribution generator (or data generator) and a metric generator. In our framework, we view the real data set as some manifold embedded in a high-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2021-08-30 Mengyu Dai , Haibin Hang

Graph Neural Networks (GNNs) present a fundamental hardware challenge by fusing irregular, memory-bound graph traversals with regular, compute-intensive dense matrix operations. While frameworks such as PyTorch Geometric (PyG) and Deep…

Machine Learning · Computer Science 2026-05-27 Anubhab , Rupesh Nasre

Morphological neurons, that is morphological operators such as dilation and erosion with learnable structuring elements, have intrigued researchers for quite some time because of the power these operators bring to the table despite their…

Machine Learning · Computer Science 2022-12-15 Ranjan Mondal , Sanchayan Santra , Soumendu Sundar Mukherjee , Bhabatosh Chanda

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Machine learning techniques that perform morphological classification of astronomical sources often suffer from a scarcity of labelled training data. Here, we focus on the case of supervised deep learning models for the morphological…

Instrumentation and Methods for Astrophysics · Physics 2023-06-16 Lennart Rustige , Janis Kummer , Florian Griese , Kerstin Borras , Marcus Brüggen , Patrick L. S. Connor , Frank Gaede , Gregor Kasieczka , Tobias Knopp , Peter Schleper

Drug Discovery is a fundamental and ever-evolving field of research. The design of new candidate molecules requires large amounts of time and money, and computational methods are being increasingly employed to cut these costs. Machine…

Machine Learning · Statistics 2021-05-28 Pietro Bongini , Monica Bianchini , Franco Scarselli

Generation of graphs is a major challenge for real-world tasks that require understanding the complex nature of their non-Euclidean structures. Although diffusion models have achieved notable success in graph generation recently, they are…

Machine Learning · Computer Science 2024-06-04 Jaehyeong Jo , Dongki Kim , Sung Ju Hwang

The joint optimisation of body-plan and control via evolutionary processes can be challenging in rich morphological spaces in which offspring can have body-plans that are very different from either of their parents. This causes a potential…

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov…

Populations and Evolution · Quantitative Biology 2024-12-30 ChenRui Duan , Zelin Zang , Siyuan Li , Yongjie Xu , Stan Z. Li

Methods allowing the synthesis of realistic cell shapes could help generate training data sets to improve cell tracking and segmentation in biomedical images. Deep generative models for cell shape synthesis require a light-weight and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 David Wiesner , Julian Suk , Sven Dummer , David Svoboda , Jelmer M. Wolterink

Understanding how cells respond to external stimuli is a central challenge in biomedical research and drug development. Current computational frameworks for modelling cellular responses remain restricted to two-dimensional representations,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Reed Naidoo , Matt De Vries , Olga Fourkioti , Vicky Bousgouni , Mar Arias-Garcia , Maria Portillo-Malumbres , Chris Bakal

Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…

Molecular Networks · Quantitative Biology 2007-05-23 Thimo Rohlf , Stefan Bornholdt

To detect bias in face recognition networks, it can be useful to probe a network under test using samples in which only specific attributes vary in some controlled way. However, capturing a sufficiently large dataset with specific control…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Nataniel Ruiz , Barry-John Theobald , Anurag Ranjan , Ahmed Hussein Abdelaziz , Nicholas Apostoloff

Generating molecular graphs with desired chemical properties driven by deep graph generative models provides a very promising way to accelerate drug discovery process. Such graph generative models usually consist of two steps: learning…

Machine Learning · Statistics 2020-06-19 Chengxi Zang , Fei Wang