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High Content Imaging (HCI) plays a vital role in modern drug discovery and development pipelines, facilitating various stages from hit identification to candidate drug characterization. Applying machine learning models to these datasets can…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Johan Fredin Haslum , Christos Matsoukas , Karl-Johan Leuchowius , Kevin Smith

While deep learning methods hitherto have achieved considerable success in medical image segmentation, they are still hampered by two limitations: (i) reliance on large-scale well-labeled datasets, which are difficult to curate due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Ziyuan Zhao , Fangcheng Zhou , Kaixin Xu , Zeng Zeng , Cuntai Guan , S. Kevin Zhou

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Semantic segmentation models trained on annotated data fail to generalize well when the input data distribution changes over extended time period, leading to requiring re-training to maintain performance. Classic Unsupervised domain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Serban Stan , Mohammad Rostami

Deep learning has demonstrated remarkable performance across various tasks in medical imaging. However, these approaches primarily focus on supervised learning, assuming that the training and testing data are drawn from the same…

Image and Video Processing · Electrical Eng. & Systems 2023-08-03 Suruchi Kumari , Pravendra Singh

Unsupervised domain adaptation (UDA) enables semantic segmentation models to generalize from a labeled source domain to an unlabeled target domain. However, existing UDA methods still struggle to bridge the domain gap due to cross-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Yang Ou , Xiongwei Zhao , Xinye Yang , Yihan Wang , Yicheng Di , Rong Yuan , Xieyuanli Chen , Xu Zhu

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

Unsupervised domain adaptation (UDA) in 3D segmentation tasks presents a formidable challenge, primarily stemming from the sparse and unordered nature of point cloud data. Especially for LiDAR point clouds, the domain discrepancy becomes…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Xidong Peng , Runnan Chen , Feng Qiao , Lingdong Kong , Youquan Liu , Yujing Sun , Tai Wang , Xinge Zhu , Yuexin Ma

Unsupervised domain adaptation (UDA) is important for applications where large scale annotation of representative data is challenging. For semantic segmentation in particular, it helps deploy on real "target domain" data models that are…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Tuan-Hung Vu , Himalaya Jain , Maxime Bucher , Matthieu Cord , Patrick Pérez

AI-enhanced segmentation of neuronal boundaries in electron microscopy (EM) images is crucial for automatic and accurate neuroinformatics studies. To enhance the limited generalization ability of typical deep learning frameworks for medical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Yuxiang An , Dongnan Liu , Weidong Cai

Domain generalisation in computational histopathology is challenging because the images are substantially affected by differences among hospitals due to factors like fixation and staining of tissue and imaging equipment. We hypothesise that…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Dhananjay Tomar , Alexander Binder , Andreas Kleppe

Deep learning models trained on medical images from a source domain (e.g. imaging modality) often fail when deployed on images from a different target domain, despite imaging common anatomical structures. Deep unsupervised domain adaptation…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Cheng Ouyang , Konstantinos Kamnitsas , Carlo Biffi , Jinming Duan , Daniel Rueckert

Accurate segmentation of brain tumors from multi-modal Magnetic Resonance (MR) images is essential in brain tumor diagnosis and treatment. However, due to the existence of domain shifts among different modalities, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Kelei He , Wen Ji , Tao Zhou , Zhuoyuan Li , Jing Huo , Xin Zhang , Yang Gao , Dinggang Shen , Bing Zhang , Junfeng Zhang

Unsupervised domain adaptation (UDA) and domain generalization (DG) enable machine learning models trained on a source domain to perform well on unlabeled or even unseen target domains. As previous UDA&DG semantic segmentation methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Lukas Hoyer , Dengxin Dai , Luc Van Gool

Medical image segmentation based on deep learning often fails when deployed on images from a different domain. The domain adaptation methods aim to solve domain-shift challenges, but still face some problems. The transfer learning methods…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Zhusi Zhong , Jie Li , Lulu Bi , Li Yang , Ihab Kamel , Rama Chellappa , Xinbo Gao , Harrison Bai , Zhicheng Jiao

Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Linkai Peng , Li Lin , Pujin Cheng , Ziqi Huang , Xiaoying Tang

The aim of this paper is to give an overview of the recent advancements in the Unsupervised Domain Adaptation (UDA) of deep networks for semantic segmentation. This task is attracting a wide interest, since semantic segmentation models…

Computer Vision and Pattern Recognition · Computer Science 2020-05-25 Marco Toldo , Andrea Maracani , Umberto Michieli , Pietro Zanuttigh

Deep learning-based segmentation methods have been widely employed for automatic glaucoma diagnosis and prognosis. In practice, fundus images obtained by different fundus cameras vary significantly in terms of illumination and intensity.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Qianbi Yu , Dongnan Liu , Chaoyi Zhang , Xinwen Zhang , Weidong Cai

Recent advances in deep learning-based medical image segmentation studies achieve nearly human-level performance in fully supervised manner. However, acquiring pixel-level expert annotations is extremely expensive and laborious in medical…

Computer Vision and Pattern Recognition · Computer Science 2023-05-19 Hyungseob Shin , Hyeongyu Kim , Sewon Kim , Yohan Jun , Taejoon Eo , Dosik Hwang

Despite its importance, unsupervised domain adaptation (UDA) on LiDAR semantic segmentation is a task that has not received much attention from the research community. Only recently, a completion-based 3D method has been proposed to tackle…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Eojindl Yi , Juyoung Yang , Junmo Kim