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This paper proposes a robust longitudinal registration method for Contrast Enhanced Spectral Mammography in monitoring neoadjuvant chemotherapy. Because breast texture intensity changes with the treatment, a non-rigid registration procedure…

Response of breast cancer to neoadjuvant chemotherapy (NAC) can be monitored using the change in visible tumor on magnetic resonance imaging (MRI). In our current workflow, seed points are manually placed in areas of enhancement likely to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Bas H. M. van der Velden , Bob D. de Vos , Claudette E. Loo , Hugo J. Kuijf , Ivana Isgum , Kenneth G. A. Gilhuijs

Aim: This study investigates treatment response prediction to neoadjuvant chemotherapy (NACT) in breast cancer patients, using longitudinal contrast-enhanced magnetic resonance images (CE-MRI) and clinical data. The goal is to develop…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Rahul Ravi , Ruizhe Li , Tarek Abdelfatah , Stephen Chan , Xin Chen

Neoadjuvant chemotherapy (NAC) is a common therapy option before the main surgery for breast cancer. Response to NAC is monitored using follow-up dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Accurate prediction of NAC…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Jonghun Kim , Hyunjin Park

In this study, we focus on brain tumor sequence registration between pre-operative and follow-up Magnetic Resonance Imaging (MRI) scans of brain glioma patients, in the context of Brain Tumor Sequence Registration challenge (BraTS-Reg…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Regular mammography screening is crucial for early breast cancer detection. By leveraging deep learning-based risk models, screening intervals can be personalized, especially for high-risk individuals. While recent methods increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Solveig Thrun , Stine Hansen , Zijun Sun , Nele Blum , Suaiba A. Salahuddin , Xin Wang , Kristoffer Wickstrøm , Elisabeth Wetzer , Robert Jenssen , Maik Stille , Michael Kampffmeyer

Effective surgical planning for breast cancer hinges on accurately predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). Diffusion-weighted MRI (DWI) and machine learning offer a non-invasive approach for early…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Shir Nitzan , Maya Gilad , Moti Freiman

Assessing cancer progression in liver CT scans is a clinical challenge, requiring a comparison of scans at different times for the same patient. Practitioners must identify existing tumors, compare them with prior exams, identify new…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Walid Yassine , Martin Charachon , Céline Hudelot , Roberto Ardon

Accurate segmentation of breast tumors in magnetic resonance images (MRI) is essential for breast cancer diagnosis, yet existing methods face challenges in capturing irregular tumor shapes and effectively integrating local and global…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Yue Zhang , Jiahua Dong , Chengtao Peng , Qiuli Wang , Dan Song , Guiduo Duan

Non-mass enhancing lesions (NME) constitute a diagnostic challenge in dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of the breast. Computer Aided Diagnosis (CAD) systems provide physicians with advanced tools for analysis,…

Image and Video Processing · Electrical Eng. & Systems 2018-09-27 Ignacio Alvarez Illan , Javier Ramirez , Juan M. Gorriz , Maria Adele Marino , Daly Avendaño , Thomas Helbich , Pascal Baltzer , Katja Pinker , Anke Meyer-Baese

Deep transfer learning using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has shown strong predictive power in characterization of breast lesions. However, pretrained convolutional neural networks (CNNs) require 2D inputs,…

Medical Physics · Physics 2019-11-11 Qiyuan Hu , Heather M. Whitney , Maryellen L. Giger

A standard treatment protocol for breast cancer entails administering neoadjuvant therapy followed by surgical removal of the tumor and surrounding tissue. Pathologists typically rely on cabinet X-ray radiographs, known as Faxitron, to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Negar Golestani , Aihui Wang , Gregory R Bean , Mirabela Rusu

This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were…

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

In breast surgical planning, accurate registration of MR images across patient positions has the potential to improve the localisation of tumours during breast cancer treatment. While learning-based registration methods have recently become…

Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Peng Xue , Jingyang Zhang , Lei Ma , Mianxin Liu , Yuning Gu , Jiawei Huang , Feihong Liua , Yongsheng Pan , Xiaohuan Cao , Dinggang Shen

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Medical image registration is a critical task that estimates the spatial correspondence between pairs of images. However, current traditional and deep-learning-based methods rely on similarity measures to generate a deforming field, which…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Qihua Dong , Hao Du , Ying Song , Yan Xu , Jing Liao

High-grade serous ovarian carcinoma (HGSOC) is characterised by significant spatial and temporal heterogeneity, typically manifesting at an advanced metastatic stage. A major challenge in treating advanced HGSOC is effectively monitoring…

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