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Breast Cancer is a major disease affecting women's health in the United States with incidence and prevalence dominant among younger women and the Black race. We analyzed the association between breast cancer characteristics with age and…

Quantitative Methods · Quantitative Biology 2024-02-21 Ishmael Nii Amartei Amartey

Triple-negative breast cancer (TNBC) is an aggressive disease with high mortality and limited treatment options, due to its lack of receptors that have targeted therapies available. The tumor microenvironment (TME) plays a critical role in…

Quantitative Methods · Quantitative Biology 2026-01-21 Kyle Adams , Julia Bruner , Salma Ameziane , Ashley Brown , Mohammed Gbadamosi , Helen Moore

Breast cancer is the leading type of cancer in women. About 10-15% of breast cancers are triple-negative breast cancer (TNBC), a subtype with the worst prognosis. Due to the lack of estrogen, progesterone and HER2 receptor expression,…

Cell Behavior · Quantitative Biology 2023-07-10 Grace Sun , Sandip Patel

We investigated the data-driven relationship between features in the tumor microenvironment (TME) and the overall and 5-year survival in triple-negative breast cancer (TNBC) and non-TNBC (NTNBC) patients by using Explainable Artificial…

Correct classification of breast cancer sub-types is of high importance as it directly affects the therapeutic options. We focus on triple-negative breast cancer (TNBC) which has the worst prognosis among breast cancer types. Using cutting…

Applications · Statistics 2021-01-13 Pieter Segaert , Marta B. Lopes , Sandra Casimiro , Susana Vinga , Peter J. Rousseeuw

Machine learning method is being applied in cancer research. In this work, we propose a method to classify the small patch of triple-negative breast cancer (TNBC) tumor and use the overall percentage of "good" patches as a marker to predict…

Medical Physics · Physics 2018-09-25 Guangyuan Yu , Xuefei Li , Herbert Levine

Introduction: Cervical cancer is the third most prevalent cancer among women in Brunei Darussalam. This study aims to report the overall survival rates and associated factors of patients diagnosed with malignant cervical cancer in Brunei…

Quantitative Methods · Quantitative Biology 2021-10-26 Fadhliah Madli , Elvynna Leong , Sok King Ong , Edwin Lim , Khairul Amilin Tengah

This study employs a robust analytical framework to uncover patterns in survival outcomes among breast cancer patients from diverse racial and geographical backgrounds. This research uses the SEER 2021 dataset to analyze breast cancer…

Machine Learning · Computer Science 2025-06-10 Ramisa Farha , Joshua O. Olukoya

Breast cancer remains a significant global health challenge, with prognosis and treatment decisions largely dependent on clinical characteristics. Accurate prediction of patient outcomes is crucial for personalized treatment strategies.…

An analysis of breast cancer incidences in women and the relationship between ethnicity and survival rate has been an ongoing study with recorded incidences of missing values in the secondary data. In this paper, we study and report the…

Quantitative Methods · Quantitative Biology 2015-03-13 Santosh Tirunagari , Norman Poh , Hajara Abdulrahman , Nawal Nemmour , David Windridge

Breast cancer is a prevalent form of cancer among women, with over 1.5 million women being diagnosed each year. Unfortunately, the survival rates for breast cancer patients in certain third-world countries, like South Africa, are alarmingly…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Brennon Maistry , Absalom E. Ezugwu

Neoadjuvant chemotherapy (NAC) is a standard-of-care treatment for locally advanced triple negative breast cancer (TNBC) before surgery. The early assessment of TNBC response to NAC would enable an oncologist to adapt the therapeutic plan…

Tissues and Organs · Quantitative Biology 2022-12-09 Guillermo Lorenzo , Angela M. Jarrett , Christian T. Meyer , Vito Quaranta , Darren R. Tyson , Thomas E. Yankeelov

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

Machine Learning · Computer Science 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

The choice of the most effective treatment may eventually be influenced by breast cancer survival prediction. To predict the chances of a patient surviving, a variety of techniques were employed, such as statistical, machine learning, and…

Machine Learning · Computer Science 2023-04-18 Khaoula Chtouki , Maryem Rhanoui , Mounia Mikram , Kamelia Amazian , Siham Yousfi

Treatments for breast cancer have continued to evolve and improve in recent years, resulting in a substantial increase in survival rates, with approximately 80\% of patients having a 10-year survival period. Given the serious impact that…

Computer Vision and Pattern Recognition · Computer Science 2022-05-26 Wilson Silva , Maria Carvalho , Carlos Mavioso , Maria J. Cardoso , Jaime S. Cardoso

Breast cancer is one of the two cancers responsible for the most deaths in women, with about 42,000 deaths each year in the US. That there are over 300,000 breast cancers newly diagnosed each year suggests that only a fraction of the…

Machine Learning · Computer Science 2024-08-30 Xia Jiang , Yijun Zhou , Alan Wells , Adam Brufsky

This report assesses different machine learning approaches to 10-year survival prediction of breast cancer patients.

Machine Learning · Computer Science 2019-11-05 Changmao Li , Han He , Yunze Hao , Caleb Ziems

Five-year cancer survival rates are widely reported and often interpreted to mean that early detection saves lives, that a late fatal diagnosis would have been prevented by earlier detection, and that increasing survival over time proves…

Methodology · Statistics 2026-03-23 Allen B. Downey

Female breast cancer (FBC) incidence rate (IR) varies greatly by counties across the United States (US). Factors responsible for such high spatial disparities are not well understood, making it challenging to design effective intervention…

Applications · Statistics 2024-01-19 Tingting Zhao , Qing Han , Jinfeng Zhang

Objective: To investigate the mechanism by which quercetin inhibits triple-negative breast cancer (TNBC) through regulating T-cell-related targets, providing a novel strategy for TNBC immunotherapy.Methods: Single-cell RNA sequencing…

Molecular Networks · Quantitative Biology 2025-08-22 Ruiqi Chen , Liang Hang , Fengyun Wang
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