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Predictive modelling is important for health data analysis and data-driven clinical decision-making. However, predictive studies are challenging to design optimally by hand when tens or even hundreds of features require selection,…

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jia-Hong Huang

The rapid growth of electronic health record (EHR) datasets opens up promising opportunities to understand human diseases in a systematic way. However, effective extraction of clinical knowledge from the EHR data has been hindered by its…

Machine Learning · Computer Science 2022-06-06 Yuesong Zou , Ahmad Pesaranghader , Aman Verma , David Buckeridge , Yue Li

While deep learning has exhibited remarkable predictive capabilities in various medical image tasks, its inherent black-box nature has hindered its widespread implementation in real-world healthcare settings. Our objective is to unveil the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Han Yuan , Lican Kang , Yong Li

Existing artificial intelligence (AI) models for diagnosing knee osteoarthritis (OA) have faced criticism for their lack of transparency and interpretability, despite achieving medical-expert-like performance. This opacity makes them…

Machine Learning · Computer Science 2023-08-21 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shuo Han , Ahmed Karam Eldaly , Solomon Sunday Oyelere

COVID-19 is a virus with high transmission rate that demands rapid identification of the infected patients to reduce the spread of the disease. The current gold-standard test, Reverse-Transcription Polymerase Chain Reaction (RT-PCR), has a…

This study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD).…

Machine Learning · Computer Science 2024-10-28 Yubo Li , Saba Al-Sayouri , Rema Padman

There have been several attempts to use deep learning based on brain fMRI signals to classify cognitive impairment diseases. However, deep learning is a hidden black box model that makes it difficult to interpret the process of…

Machine Learning · Computer Science 2024-11-20 Jeong-Jae Kim , Yeseul Jeon , SuMin Yu , Junggu Choi , Sanghoon Han

Chronic Kidney Disease (CKD) is a major global health issue which is affecting million people around the world and with increasing rate of mortality. Mitigation of progression of CKD and better patient outcomes requires early detection.…

Artificial Intelligence · Computer Science 2025-04-08 Md. Ehsanul Haque , S. M. Jahidul Islam , Jeba Maliha , Md. Shakhauat Hossan Sumon , Rumana Sharmin , Sakib Rokoni

Accurate diagnosis of skin diseases remains a significant challenge due to the complex and diverse visual features present in dermatoscopic images, often compounded by a lack of interpretability in existing purely visual diagnostic models.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Kexin Yu , Zihan Xu , Jialei Xie , Carter Adams

The rising incidence of skin cancer, coupled with limited public awareness and a shortfall in clinical expertise, underscores an urgent need for advanced diagnostic aids. Artificial Intelligence (AI) has emerged as a promising tool in this…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Hamideh Khaleghpour , Brett McKinney

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Access to dermatological care is a major issue, with an estimated 3 billion people lacking access to care globally. Artificial intelligence (AI) may aid in triaging skin diseases. However, most AI models have not been rigorously assessed on…

Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these…

Human-Computer Interaction · Computer Science 2025-01-29 Olya Rezaeian , Alparslan Emrah Bayrak , Onur Asan

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

Artificial intelligence (AI) provides a promising substitution for streamlining COVID-19 diagnoses. However, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing a…

The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…

Artificial Intelligence · Computer Science 2025-07-22 Mohammad Mashayekhi , Sara Ahmadi Majd , Arian AmirAmjadi , Parsa Hosseini

Applications of large language models (LLMs) like ChatGPT have potential to enhance clinical decision support through conversational interfaces. However, challenges of human-algorithmic interaction and clinician trust are poorly understood.…