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The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Areas where Artificial Intelligence (AI) & related fields are finding their applications are increasing day by day, moving from core areas of computer science they are finding their applications in various other domains.In recent times…

Machine Learning · Computer Science 2016-07-19 Sahil Sharma , Vinod Sharma , Atul Sharma

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

AI-assisted gait analysis holds promise for improving Parkinson's Disease (PD) care, but current clinical dashboards lack transparency and offer no meaningful way for clinicians to interrogate or contest AI decisions. To address this issue,…

Human-Computer Interaction · Computer Science 2025-12-11 Loc Phuc Truong Nguyen , Hung Thanh Do , Hung Truong Thanh Nguyen , Hung Cao

Medical Large Vision-Language Models (Med-LVLMs) demonstrate significant potential in healthcare, but their reliance on general medical data and coarse-grained global visual understanding limits them in intelligent ophthalmic diagnosis.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Sijing Li , Tianwei Lin , Lingshuai Lin , Wenqiao Zhang , Jiang Liu , Xiaoda Yang , Juncheng Li , Yucheng He , Xiaohui Song , Jun Xiao , Yueting Zhuang , Beng Chin Ooi

One of the most serious corneal disorders, keratoconus is difficult to diagnose in its early stages and can result in blindness. This illness, which often appears in the second decade of life, affects people of all sexes and races.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 AKM Enzam-Ul Haque , Golam Rabbany , Md. Siam

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying…

Quantitative Methods · Quantitative Biology 2025-05-06 Yubo Li , Rema Padman

Background: Acute kidney injury (AKI) is a common complication in hospitalized patients and a common cause for chronic kidney disease (CKD) and increased hospital cost and mortality. By timely detection of AKI and AKI progression, effective…

Inherited retinal diseases (IRDs) are a diverse group of genetic disorders that lead to progressive vision loss and are a major cause of blindness in working-age adults. The complexity and heterogeneity of IRDs pose significant challenges…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Han Trinh , Jordan Vice , Jason Charng , Zahra Tajbakhsh , Khyber Alam , Fred K. Chen , Ajmal Mian

Omics data facilitate the gain of novel insights into the pathophysiology of diseases and, consequently, their diagnosis, treatment, and prevention. To that end, it is necessary to integrate omics data with other data types such as…

Artificial intelligence (AI) algorithms using deep learning have advanced the classification of skin disease images; however these algorithms have been mostly applied "in silico" and not validated clinically. Most dermatology AI algorithms…

Computer Vision and Pattern Recognition · Computer Science 2021-05-24 Roxana Daneshjou , Carrie Kovarik , Justin M Ko

Artificial intelligence (AI) provides considerable opportunities to assist human work. However, one crucial challenge of human-AI collaboration is that many AI algorithms operate in a black-box manner where the way how the AI makes…

Human-Computer Interaction · Computer Science 2024-06-13 Julian Senoner , Simon Schallmoser , Bernhard Kratzwald , Stefan Feuerriegel , Torbjørn Netland

The main challenges hindering the adoption of deep learning-based systems in clinical settings are the scarcity of annotated data and the lack of interpretability and trust in these systems. Concept Bottleneck Models (CBMs) offer inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Cristiano Patrício , Luís F. Teixeira , João C. Neves

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

Artificial intelligence (AI) systems have substantially improved dermatologists' diagnostic accuracy for melanoma, with explainable AI (XAI) systems further enhancing clinicians' confidence and trust in AI-driven decisions. Despite these…

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and…

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

The black-box nature of deep learning models has raised concerns about their interpretability for successful deployment in real-world clinical applications. To address the concerns, eXplainable Artificial Intelligence (XAI) aims to provide…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Junlin Hou , Jilan Xu , Hao Chen