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With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to…

Molecular Networks · Quantitative Biology 2010-01-28 Sitabhra Sinha , T Jesan , Nivedita Chatterjee

In order to investigate the evolutionary process of many deterministic Dynamical systems with unfixed parameter, a set of dynamical models with parameter changing continuously and the accumulation of this change might be large is introduced…

comp-gas · Physics 2008-02-03 H. P. Fang

We present log-linear dynamical systems, a dynamical system model for positive quantities. We explain the connection to linear dynamical systems and show how convex optimization can be used to identify and control log-linear dynamical…

Optimization and Control · Mathematics 2020-02-07 Steven Diamond

Genetic systems with multiple loci can have complex dynamics. For example, mean fitness need not always increase and stable cycling is possible. Here, we study the dynamics of a genetic system inspired by the molecular biology of…

Populations and Evolution · Quantitative Biology 2019-05-10 Timothy W. Russell , Matthew J. Russell , Francisco Úbeda , Vincent A. A. Jansen

In physics, complex systems are often simplified into minimal, solvable models that retain only the core principles. In machine learning, layerwise linear models (e.g., linear neural networks) act as simplified representations of neural…

This paper studies the data-driven control of unknown linear-threshold network dynamics to stabilize the state to a reference value. We consider two types of controllers: (i) a state feedback controller with feed-forward reference input and…

Systems and Control · Electrical Eng. & Systems 2025-10-03 Xuan Wang , Duy Duong-Tran , Jorge Cortés

Nonlinear dynamical systems may be exposed to tipping points, critical thresholds at which small changes in the external inputs or in the systems parameters abruptly shift the system to an alternative state with a contrasting dynamical…

Chaotic Dynamics · Physics 2016-10-07 Everton S. Medeiros , Iberê L. Caldas , Murilo S. Baptista , Ulrike Feudel

Ring topologies of repressing genes have qualitatively different long-term dynamics if the number of genes is odd (they oscillate) or even (they exhibit bistability). However, these attractors may not fully explain the observed behavior in…

Molecular Networks · Quantitative Biology 2010-01-22 Natalja Strelkowa , Mauricio Barahona

Complex networks theory has commonly been used for modelling and understanding the interactions taking place between the elements composing complex systems. More recently, the use of generative models has gained momentum, as they allow…

Physics and Society · Physics 2016-05-19 Massimiliano Zanin , Marco Correia , Pedro A. C. Sousa , Jorge Cruz

We present sufficient conditions under which a given linear nonautonomous system and its nonlinear perturbation are topologically conjugated. Our conditions are of a very general form and provided that the nonlinear perturbations are…

Classical Analysis and ODEs · Mathematics 2022-10-12 Lucas Backes , Davor Dragičević

This article describes a numerical procedure designed to tune the parameters of periodically-driven dynamical systems to a state in which they exhibit rich dynamical behavior. This is achieved by maximizing the diversity of subharmonic…

Chaotic Dynamics · Physics 2017-02-13 Leandro M. Alonso

Inference of gene regulatory networks has been an active area of research for around 20 years, leading to the development of sophisticated inference algorithms based on a variety of assumptions and approaches. With the always increasing…

Molecular Networks · Quantitative Biology 2022-11-03 Malvina Marku , Vera Pancaldi

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

Over the past few years, neural networks have re-emerged as powerful machine-learning models, yielding state-of-the-art results in fields such as image recognition and speech processing. More recently, neural network models started to be…

Computation and Language · Computer Science 2015-10-06 Yoav Goldberg

We consider the basic features of complex dynamic and control systems, including systems having hierarchical structure. Special attention is paid to the problems of design and synthesis of complex systems and control models, and to the…

Computational Engineering, Finance, and Science · Computer Science 2008-12-25 Armen Bagdasaryan

We approximate a chain recurrent dynamical system by periodic dynamical systems. This is similar to the well known Bohr theorem on approximation of almost periodic functions by periodic functions.

Dynamical Systems · Mathematics 2008-04-05 Vladimir Azarin

The cell cycle duration is a variable cellular phenotype that underlies long-term population growth and age structures. By analyzing the stationary solutions of a branching process with heritable cell division times, we demonstrate…

Populations and Evolution · Quantitative Biology 2021-01-04 Takashi Nozoe , Edo Kussell

We present a novel approach to modelling and learning vector fields from physical systems using neural networks that explicitly satisfy known linear operator constraints. To achieve this, the target function is modelled as a linear…

Machine Learning · Statistics 2021-04-29 Johannes Hendriks , Carl Jidling , Adrian Wills , Thomas Schön

We characterize the distributions of short cycles in a large metabolic network previously shown to have small world characteristics and a power law degree distribution. Compared with three classes of random networks, including Erdoes-Renyi…

Condensed Matter · Physics 2007-05-23 Petra M. Gleiss , Peter F. Stadler , Andreas Wagner , David A. Fell

Graph Theoretic Process Network Synthesis is described as an introduction to biological networks. Genetic, protein and metabolic systems are considered. The theoretical work of Kauffman is discussed and amplified by critical property…

Biological Physics · Physics 2007-05-23 L. Papp , S. Bumble , F. Friedler , L. T. Fan