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Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Achieving advanced machine intelligence remains a central challenge in AI research, often approached through scaling neural architectures and generative models. However, biological systems offer a broader repertoire of strategies for…

Neurons and Cognition · Quantitative Biology 2026-05-26 Giovanni Pezzulo , Michael Levin

We propose a design principle for the learning circuits of the biological brain. The principle states that almost any dendritic weights updated via heterosynaptic plasticity can implement a generalized and efficient class of gradient-based…

Neurons and Cognition · Quantitative Biology 2025-05-06 Liu Ziyin , Isaac Chuang , Tomaso Poggio

The goal of continual learning (CL) is to learn different tasks over time. The main desiderata associated with CL are to maintain performance on older tasks, leverage the latter to improve learning of future tasks, and to introduce minimal…

Machine Learning · Computer Science 2022-06-22 Mustafa Burak Gurbuz , Constantine Dovrolis

Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

Many recent generative models make use of neural networks to transform the probability distribution of a simple low-dimensional noise process into the complex distribution of the data. This raises the question of whether biological networks…

Neural and Evolutionary Computing · Computer Science 2018-02-07 Hesham Mostafa , Gert Cauwenberghs

This study investigates how dynamical systems may be learned and modelled with a neuromorphic network which is itself a dynamical system. The neuromorphic network used in this study is based on a complex electrical circuit comprised of…

Disordered Systems and Neural Networks · Physics 2025-10-24 Yinhao Xu , Georg A. Gottwald , Zdenka Kuncic

Convolutional neural networks (CNNs) are now the de facto solution for computer vision problems thanks to their impressive results and ease of learning. These networks are composed of layers of connected units called artificial neurons,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Loïc Cordone , Benoît Miramond , Sonia Ferrante

Neuromorphic computing systems comprise networks of neurons that use asynchronous events for both computation and communication. This type of representation offers several advantages in terms of bandwidth and power consumption in…

Hardware Architecture · Computer Science 2017-11-07 Saber Moradi , Ning Qiao , Fabio Stefanini , Giacomo Indiveri

The rapid proliferation of Deep Learning is increasingly constrained by its heavy reliance on high-performance hardware, particularly Graphics Processing Units (GPUs). These specialized accelerators are not only prohibitively expensive and…

Machine Learning · Computer Science 2026-01-06 Emrah Mete , Emin Erkan Korkmaz

Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs. engineering mechanisms are, by definition, dramatically different and can…

Robotics · Computer Science 2017-10-25 Francisco J Valero-Cuevas , Marco Santello

The development of artificial intelligence (AI) and robotics are both based on the tenet of "science and technology are people-oriented", and both need to achieve efficient communication with the human brain. Based on multi-disciplinary…

Neurons and Cognition · Quantitative Biology 2024-06-27 Shengjie Zheng , Ling Liu , Junjie Yang , Jianwei Zhang , Tao Su , Bin Yue , Xiaojian Li

How the very first nervous systems evolved remains a fundamental open question. Molecular and genomic techniques have revolutionized our knowledge of the molecular ingredients behind this transition but not yet provided a clear picture of…

Neurons and Cognition · Quantitative Biology 2017-10-31 Ronald A. J. van Elburg , Oltman O. de Wiljes , Michael Biehl , Fred A. Keijzer

Neural reflectance models are capable of reproducing the spatially-varying appearance of many real-world materials at different scales. Unfortunately, existing techniques such as NeuMIP have difficulties handling materials with strong…

Graphics · Computer Science 2024-04-25 Bowen Xue , Shuang Zhao , Henrik Wann Jensen , Zahra Montazeri

Recently, the use of bio-inspired learning techniques such as Hebbian learning and its closely-related Spike-Timing-Dependent Plasticity (STDP) variant have drawn significant attention for the design of compute-efficient AI systems that can…

Neural and Evolutionary Computing · Computer Science 2024-11-19 Ali Safa

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

Neurons and Cognition · Quantitative Biology 2026-04-27 Gabriele Scheler

Dynamics play a critical role in computation. The principled evolution of states over time enables both biological and artificial networks to represent and integrate information to make decisions. In the past few decades, significant…

Neurons and Cognition · Quantitative Biology 2023-11-28 Jason Z. Kim , Bart Larsen , Linden Parkes

The enormous amount of data generated nowadays worldwide is increasingly triggering the search for unconventional and more efficient ways of processing and classifying information, eventually able to transcend the conventional…

Adaptation and Self-Organizing Systems · Physics 2020-04-22 Ewelina Wlaźlak , Dawid Przyczyna , Rafael Gutierrez , Gianaurelio Cuniberti , Konrad Szaciłowski

In vivo, eukaryotic cells are embedded in a matrix environment, where they grow and develop. Generally, this extracellular matrix (ECM) is an anisotropic fibrous structure, through which macromolecules and biochemical signaling molecules at…

Biological Physics · Physics 2020-01-06 David Gomez , Sari Natan , Yair Shokef , Ayelet Lesman

This review explores biologically inspired learning as a model for intelligent robot control and sensing technology on the basis of specific examples. Hebbian synaptic learning is discussed as a functionally relevant model for machine…

Robotics · Computer Science 2022-02-28 Birgitta Dresp-Langley