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We report a detailed study of neuromorphic switching behaviour in inherently complex percolating networks of self-assembled metal nanoparticles. We show that variation of the strength and duration of the electric field applied to this…

Disordered Systems and Neural Networks · Physics 2019-03-06 S. K. Bose , S. Shirai , J. B. Mallinson , S. A. Brown

In realistic neural circuits, both neurons and synapses are coupled in dynamics with separate time scales. The circuit functions are intimately related to these coupled dynamics. However, it remains challenging to understand the intrinsic…

Neurons and Cognition · Quantitative Biology 2025-11-11 Wenkang Du , Haiping Huang

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Chemical and electrical synapses shape the dynamics of neuronal networks. Numerous theoretical studies have investigated how each of these types of synapses contributes to the generation of neuronal oscillations, but their combined effect…

Adaptation and Self-Organizing Systems · Physics 2019-10-30 Bastian Pietras , Federico Devalle , Alex Roxin , Andreas Daffertshofer , Ernest Montbrió

Many biological and artificial transport channels function without direct input of metabolic energy during a transport event and without structural rearrangements involving transitions from a 'closed' to an 'open' state. Nevertheless, such…

Subcellular Processes · Quantitative Biology 2009-11-13 Anton Zilman

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…

Biological Physics · Physics 2018-02-14 Yoshihiko Hasegawa

Several analog and digital brain-inspired electronic systems have been recently proposed as dedicated solutions for fast simulations of spiking neural networks. While these architectures are useful for exploring the computational properties…

Emerging Technologies · Computer Science 2017-11-08 Elisabetta Chicca , Fabio Stefanini , Chiara Bartolozzi , Giacomo Indiveri

Organic neuromorphic device networks can accelerate neural network algorithms and directly integrate with microfluidic systems or living tissues. Proposed devices based on the bio-compatible conductive polymer PEDOT:PSS have shown high…

Emerging Technologies · Computer Science 2022-12-12 Daniel Felder , Katerina Muche , John Linkhorst , Matthias Wessling

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Neurons and Cognition · Quantitative Biology 2018-10-30 Y. Dabaghian

Throughout evolution the brain has mastered the art of processing real-world inputs through networks of interlinked spiking neurons. Synapses have emerged as key elements that, owing to their plasticity, are merging neuron-to-neuron…

Neuromorphic computing promises to transform AI systems by enabling them to perceive, respond to, and adapt swiftly and accurately to dynamic data and user interactions. However, traditional silicon-based and hybrid electronic technologies…

Optics · Physics 2025-07-09 Robert Otupiri , Ripalta Stabile

Predicting whether a chemical structure shares a desired biological effect can have a significant impact for in-silico compound screening in early drug discovery. In this study, we developed a deep learning model where compound structures…

Quantitative Methods · Quantitative Biology 2020-04-03 C. Fotis , N. Meimetis , A. Sardis , L. G. Alexopoulos

Future brain-machine interfaces, prosthetics, and intelligent soft robotics will require integrating artificial neuromorphic devices with biological systems. Due to their poor biocompatibility, circuit complexity, low energy efficiency, and…

In the mammalian nervous system, various synaptic plasticity rules act, either individually or synergistically, and over wide-ranging timescales to dictate the processes that enable learning and memory formation. To mimic biological…

Disordered Systems and Neural Networks · Physics 2021-06-11 Syed Ghazi Sarwat , Benedikt Kersting , Timoleon Moraitis , Vara Prasad Jonnalagadda , Abu Sebastian

Many experiments have evidenced that electrical and chemical synapses -- hybrid synapses -- coexist in most organisms and brain structures. The role of electrical and chemical synapse connection in diversity of neural activity generation…

Neurons and Cognition · Quantitative Biology 2021-08-11 Kesheng Xu , Jean Paul Maidana , Patricio Orio

In contrast to biological neural circuits, conventional artificial neural networks are commonly organized as strictly hierarchical architectures that exclude direct connections among neurons within the same layer. Consequently, information…

Neural and Evolutionary Computing · Computer Science 2025-11-17 Rafiad Sadat Shahir , Zayed Humayun , Mashrufa Akter Tamim , Shouri Saha , Md. Golam Rabiul Alam , Abu Mohammad Khan

Motor Imagery (MI) is an emerging Brain-Computer Interface (BCI) paradigm where a person imagines body movements without physical action. By decoding scalp-recorded electroencephalography (EEG) signals, BCIs establish direct communication…

Human-Computer Interaction · Computer Science 2026-04-14 Jiani Cao , Kun Wang , Yang Liu , Zhenjiang Li

Spike-based communication between biological neurons is sparse and unreliable. This enables the brain to process visual information from the eyes efficiently. Taking inspiration from biology, artificial spiking neural networks coupled with…

Neural and Evolutionary Computing · Computer Science 2019-05-07 Jacques Kaiser , Alexander Friedrich , J. Camilo Vasquez Tieck , Daniel Reichard , Arne Roennau , Emre Neftci , Rüdiger Dillmann

Conventional Artificial Intelligence (AI) systems are running into limitations in terms of training time and energy. Following the principles of the human brain, spiking neural networks trained with unsupervised learning offer a faster,…

Superconductivity · Physics 2025-04-04 Ken Segall , Leon Nichols , Will Friend , Steven B. Kaplan