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Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation…

Machine Learning · Computer Science 2022-12-09 Weina Jin , Xiaoxiao Li , Mostafa Fatehi , Ghassan Hamarneh

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad

Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Deep learning-based medical image analysis faces a significant barrier due to the lack of interpretability. Conventional explainable AI (XAI) techniques, such as Grad-CAM and SHAP, often highlight regions outside clinical interests. To…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuhao Zhang , Mingcheng Zhu , Zhiyao Luo

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

For the deployment of artificial intelligence (AI) in high-risk settings, such as healthcare, methods that provide interpretability/explainability or allow fine-grained error analysis are critical. Many recent methods for…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Roxana Daneshjou , Mert Yuksekgonul , Zhuo Ran Cai , Roberto Novoa , James Zou

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

In computer vision, explainable AI (xAI) methods seek to mitigate the 'black-box' problem by making the decision-making process of deep learning models more interpretable and transparent. Traditional xAI methods concentrate on visualizing…

Human-Computer Interaction · Computer Science 2024-08-15 Hyeonggeun Yun

Remarkable success of modern image-based AI methods and the resulting interest in their applications in critical decision-making processes has led to a surge in efforts to make such intelligent systems transparent and explainable. The need…

Artificial Intelligence · Computer Science 2020-11-30 Adriano Lucieri , Muhammad Naseer Bajwa , Andreas Dengel , Sheraz Ahmed

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

Artificial Intelligence · Computer Science 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

As deep learning models gain attraction in medical data, ensuring transparent and trustworthy decision-making is essential. In skin cancer diagnosis, while advancements in lesion detection and classification have improved accuracy, the…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Sadia Kamal , Tim Oates

The healthcare industry has been revolutionized by the convergence of Artificial Intelligence of Medical Things (AIoMT), allowing advanced data-driven solutions to improve healthcare systems. With the increasing complexity of Artificial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-08 Al Amin , Kamrul Hasan , Saleh Zein-Sabatto , Deo Chimba , Imtiaz Ahmed , Tariqul Islam

Deep learning based medical image classifiers have shown remarkable prowess in various application areas like ophthalmology, dermatology, pathology, and radiology. However, the acceptance of these Computer-Aided Diagnosis (CAD) systems in…

Voice disorders affect a significant portion of the population, and the ability to diagnose them using automated, non-invasive techniques would represent a substantial advancement in healthcare, improving the quality of life of patients.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-25 Davide Ghia , Gabriele Ciravegna , Alkis Koudounas , Marco Fantini , Erika Crosetti , Giovanni Succo , Tania Cerquitelli

Automated dermoscopic image analysis has witnessed rapid growth in diagnostic performance. Yet adoption faces resistance, in part, because no evidence is provided to support decisions. In this work, an approach for evidence-based…

Computer Vision and Pattern Recognition · Computer Science 2018-08-03 Noel C. F. Codella , Chung-Ching Lin , Allan Halpern , Michael Hind , Rogerio Feris , John R. Smith

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…