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Clustered binary data with a large number of covariates have become increasingly common in many scientific disciplines. This paper develops an asymptotic theory for generalized estimating equations (GEE) analysis of clustered binary data…

Statistics Theory · Mathematics 2011-03-10 Lan Wang

Penalized generalized estimating equations (PGEE) stabilize point estimation for longitudinal binary data under near-separation, but inference still depends on how the sandwich variance is corrected. Existing corrections for PGEE can…

Methodology · Statistics 2026-04-22 Awan Afiaz , M. Shafiqur Rahman

In this paper, we present a generalized estimating equations based estimation approach and a variable selection procedure for single-index models when the observed data are clustered. Unlike the case of independent observations,…

Methodology · Statistics 2011-08-08 Peng Lai , Qihua Wang , Heng Lian

The method of generalized estimating equations (GEE) is popular in the biostatistics literature for analyzing longitudinal binary and count data. It assumes a generalized linear model (GLM) for the outcome variable, and a working…

Methodology · Statistics 2016-06-03 Aristidis K. Nikoloulopoulos

Regression models applied to network data where node attributes are the dependent variables poses a methodological challenge. As has been well studied, naive regression neither properly accounts for community structure, nor does it account…

Methodology · Statistics 2024-02-16 Riddhi Pratim Ghosh , Jukka-Pekka Onnela , Ian Barnett

Generalized estimating equation (GEE) is widely adopted for regression modeling for longitudinal data, taking account of potential correlations within the same subjects. Although the standard GEE assumes common regression coefficients among…

Methodology · Statistics 2022-07-11 Tsubasa Ito , Shonosuke Sugasawa

Generalized estimating equations (GEE; Liang & Zeger 1986) for general vector regression settings are examined. When the response vectors are of mixed type (e.g. continuous-binary response pairs), the GEE approach is a semiparametric…

Methodology · Statistics 2020-10-08 Alan Huang

Design and analysis of cluster randomized trials must take into account correlation among outcomes from the same clusters. When applying standard generalized estimating equations (GEE), the first-order (e.g. treatment) effects can be…

Methodology · Statistics 2018-04-18 Tom Chen , Eric Tchetgen Tchetgen , Rui Wang

Modeling correlated or highly stratified multiple-response data becomes a common data analysis task due to modern data monitoring facilities and methods. Generalized estimating equations (GEE) is one of the popular statistical methods for…

Methodology · Statistics 2019-03-05 Zimu Chen , Zhanfeng Wang , Yuan-chin Ivan Chang

Extending generalized estimating equations (GEE) to ordinal response data requires a conversion of the ordinal response to a vector of binary category indicators. That leads to a rather complicated association structure, and the…

Methodology · Statistics 2017-05-23 Aristidis K. Nikoloulopoulos

Generalized estimating equations (GEE) are widely used to analyze longitudinal data; however, they are not appropriate for heteroscedastic data, because they only estimate regressor effects on the mean response{\textemdash}and therefore do…

Methodology · Statistics 2020-12-29 Amadou Barry , Karim Oualkacha , Arthur Charpentier

Generalized linear models are a popular tool in applied statistics, with their maximum likelihood estimators enjoying asymptotic Gaussianity and efficiency. As all models are wrong, it is desirable to understand these estimators' behaviours…

Methodology · Statistics 2024-12-10 Elliot H. Young , Rajen D. Shah

Clustered and longitudinal data are pervasive in scientific studies, from prenatal health programs to clinical trials and public health surveillance. Such data often involve non-Gaussian responses--including binary, categorical, and count…

Methodology · Statistics 2025-09-19 Yibo Wang , Chenlei Leng , Cheng Yong Tang

Mutual information is a measure of the dependence between random variables that has been used successfully in myriad applications in many fields. Generalized mutual information measures that go beyond classical Shannon mutual information…

Information Theory · Computer Science 2021-07-30 Kevin R. Moon , Kumar Sricharan , Alfred O. Hero

Machine learning applications require fast and reliable per-sample uncertainty estimation. A common approach is to use predictive distributions from Bayesian or approximation methods and additively decompose uncertainty into aleatoric…

Machine Learning · Computer Science 2026-02-10 H. Martin Gillis , Isaac Xu , Thomas Trappenberg

Fine stratification is a popular design as it permits the stratification to be carried out to the fullest possible extent. Some examples include the Current Population Survey and National Crime Victimization Survey both conducted by the…

Methodology · Statistics 2026-03-09 Sepideh Mosaferi

Generalized estimating equations (GEE) is one of the most commonly used methods for marginal regression analysis of longitudinal data, especially with discrete outcomes. The GEE method models the association among the responses of a subject…

Methodology · Statistics 2018-03-20 Gul Inan , Mahbub A. H. M. Latif , John Preisser

High-dimensional longitudinal data have become increasingly prevalent in recent studies, and penalized generalized estimating equations (GEEs) are often used to model such data. However, the desirable properties of the GEE method can break…

Methodology · Statistics 2025-01-03 Yue Ma , Haofeng Wang , Xuejun Jiang

The Generalized Estimating Equations (GEE) approach is a widely used statistical method for analyzing longitudinal data and clustered data in clinic studies. In dentistry, due to multiple outcomes obtained from one patient, the outcomes…

Methodology · Statistics 2025-02-25 Hoi-Jeong Lim , Soo-Hyeon Park

A common approach to the claims reserving problem is based on generalized linear models (GLM). Within this framework, the claims in different origin and development years are assumed to be independent variables. If this assumption is…

Applications · Statistics 2013-06-18 Šárka Hudecová , Michal Pešta
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