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Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Mutyyba Asghar , Ahmad Raza Shahid , Akhtar Jamil , Kiran Aftab , Syed Ather Enam

Multi-phase CT is widely adopted for the diagnosis of kidney cancer due to the complementary information among phases. However, the complete set of multi-phase CT is often not available in practical clinical applications. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Kwang-Hyun Uhm , Seung-Won Jung , Moon Hyung Choi , Sung-Hoo Hong , Sung-Jea Ko

Cancer evolves continuously over time through a complex interplay of genetic, epigenetic, microenvironmental, and phenotypic changes. This dynamic behavior drives uncontrolled cell growth, metastasis, immune evasion, and therapy resistance,…

Quantitative Methods · Quantitative Biology 2025-07-08 Luoting Zhuang , Stephen H. Park , Steven J. Skates , Ashley E. Prosper , Denise R. Aberle , William Hsu

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Recent developments in spatial omics technologies have enabled the generation of high dimensional molecular data, such as transcriptomes, proteomes, and epigenomes, within their spatial tissue context, either through coprofiling on the same…

Quantitative Methods · Quantitative Biology 2026-01-21 Esra Busra Isik , Yusuf Hakan Usta , Haozhe Liu , Maryam Riazi , William Roach , Hongpeng Zhou , Magnus Rattray , Sokratia Georgaka

Precision cancer medicine aims to determine the optimal treatment for each patient. In-vitro cancer drug sensitivity screens combined with multi-omics characterization of the cancer cells have become an important tool to achieve this aim.…

Methodology · Statistics 2024-03-14 Zhi Zhao , Marco Banterle , Alex Lewin , Manuela Zucknick

Cutaneous malignancies demand early detection for favorable outcomes, yet current diagnostics suffer from inter-observer variability and access disparities. While AI shows promise, existing dermatological systems are limited by homogeneous…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sher Khan , Raz Muhammad , Adil Hussain , Muhammad Sajjad , Muhammad Rashid

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Molecular Networks · Quantitative Biology 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

Semi-supervised learning addresses the issue of limited annotations in medical images effectively, but its performance is often inadequate for complex backgrounds and challenging tasks. Multi-modal fusion methods can significantly improve…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Dongdong Meng , Sheng Li , Hao Wu , Guoping Wang , Xueqing Yan

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Pathologists routinely alternate between different magnifications when examining Whole-Slide Images, allowing them to evaluate both broad tissue morphology and intricate cellular details to form comprehensive diagnoses. However, existing…

The Internet of Medical Things (IoMT) has dramatically benefited medical professionals that patients and physicians can access from all regions. Although the automatic detection and prediction of diseases such as melanoma and leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Alhassan Mabrouk , Abdelghani Dahou , Mohamed Abd Elaziz , Rebeca P. Díaz Redondo , Mohammed Kayed

High-confidence prediction of complex traits such as disease risk or drug response is an ultimate goal of personalized medicine. Although genome-wide association studies have discovered thousands of well-replicated polymorphisms associated…

Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…

Quantitative Methods · Quantitative Biology 2023-05-04 Jonas C. Ditz , Bernhard Reuter , Nico Pfeifer

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Gene studies are crucial for fields such as protein structure prediction, drug discovery, and cancer genomics, yet they face challenges in fully utilizing the vast and diverse information available. Gene studies require clean, factual…

Databases · Computer Science 2024-12-18 Yuwei Miao , Yuzhi Guo , Hehuan Ma , Jingquan Yan , Feng Jiang , Weizhi An , Jean Gao , Junzhou Huang

Glioma, the prevalent primary brain tumor, exhibits diverse aggressiveness levels and prognoses. Precise classification of glioma is paramount for treatment planning and predicting prognosis. This study aims to develop an algorithm to fuse…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Kiranmayee Janardhan , Christy Bobby Thomas

Motivation: Cancer is heterogeneous, affecting the precise approach to personalized treatment. Accurate subtyping can lead to better survival rates for cancer patients. High-throughput technologies provide multiple omics data for cancer…

Machine Learning · Computer Science 2022-08-01 Hai Yang , Yuhang Sheng , Yi Jiang , Xiaoyang Fang , Dongdong Li , Jing Zhang , Zhe Wang
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