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Heart Disease has become one of the most serious diseases that has a significant impact on human life. It has emerged as one of the leading causes of mortality among the people across the globe during the last decade. In order to prevent…

Machine Learning · Computer Science 2022-06-08 Muhammad Salman Pathan , Avishek Nag , Muhammad Mohisn Pathan , Soumyabrata Dev

Disease complications can alter vascular network morphology and disrupt tissue functioning. Diabetic retinopathy, for example, is a complication of types 1 and 2 diabetes mellitus that can cause blindness. Microvascular diseases are…

Quantitative Methods · Quantitative Biology 2022-09-13 John T. Nardini , Charles W. J. Pugh , Helen M. Byrne

Deep fully convolutional neural network (FCN) based architectures have shown great potential in medical image segmentation. However, such architectures usually have millions of parameters and inadequate number of training samples leading to…

Computer Vision and Pattern Recognition · Computer Science 2018-01-17 Mahendra Khened , Varghese Alex Kollerathu , Ganapathy Krishnamurthi

Carotid atherosclerosis is the major cause of ischemic stroke resulting in significant rates of mortality and disability annually. Early diagnosis of such cases is of great importance, since it enables clinicians to apply a more effective…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Theofanis Ganitidis , Maria Athanasiou , Kalliopi Dalakleidi , Nikos Melanitis , Spyretta Golemati , Konstantina S Nikita

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

Various types of atherosclerotic plaque and varying grades of stenosis could lead to different management of patients with coronary artery disease. Therefore, it is crucial to detect and classify the type of coronary artery plaque, as well…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Majd Zreik , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Tim Leiner , Max A. Viergever , Ivana Isgum

The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt…

Computers and Society · Computer Science 2022-12-16 Nidhi Sinha , Teena Jangid , Amit M. Joshi , Saraju P. Mohanty

Coronary artery disease (CAD) remains the leading cause of death worldwide. Patients with suspected CAD undergo coronary CT angiography (CCTA) to evaluate the risk of cardiovascular events and determine the treatment. Clinical analysis of…

Our long-range goal is to improve current whole-heart CT calcium score by extracting quantitative features from individual calcifications. We performed deconvolution to improve small calcifications assessment which challenge conventional CT…

Thin-cap fibroatheroma (TCFA) and plaque rupture have been recognized as the most frequent risk factor for thrombosis and acute coronary syndrome. Intravascular optical coherence tomography (IVOCT) can identify TCFA and assess cap…

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

In this study, hypertension is utilized as an indicator of individual vascular damage. This damage can be identified through machine learning techniques, providing an early risk marker for potential major cardiovascular events and offering…

We present ASCENDgpt, a transformer-based model specifically designed for cardiovascular risk prediction from longitudinal electronic health records (EHRs). Our approach introduces a novel phenotype-aware tokenization scheme that maps…

Computation and Language · Computer Science 2025-09-08 Chris Sainsbury , Andreas Karwath

The electrocardiogram (ECG) is a vital tool for diagnosing heart diseases. However, many disease patterns are derived from outdated datasets and traditional stepwise algorithms with limited accuracy. This study presents a method for direct…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Oğuzhan Büyüksolak , İlkay Öksüz

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

The identification of vascular networks is an important topic in the medical image analysis community. While most methods focus on single vessel tracking, the few solutions that exist for tracking complete vascular networks are usually…

Computer Vision and Pattern Recognition · Computer Science 2017-06-09 Dario Augusto Borges Oliveira , Laura Leal-Taixe , Raul Queiroz Feitosa , Bodo Rosenhahn

We present a mathematical study of the emergence of phenotypic heterogeneity in vascularised tumours. Our study is based on formal asymptotic analysis and numerical simulations of a system of non-local parabolic equations that describes the…

Tissues and Organs · Quantitative Biology 2021-03-26 Chiara Villa , Mark A. J. Chaplain , Tommaso Lorenzi

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Morphological features of small vessels provide invaluable information regarding underlying tissue, especially in cancerous tumors. This paper introduces methods for obtaining quantitative morphological features from microvasculature images…

Medical Physics · Physics 2018-12-11 Siavash Ghavami , Mahdi Bayat , Mostafa Fatemi , Azra Alizad

The segmentation and analysis of coronary arteries from intravascular optical coherence tomography (IVOCT) is an important aspect of diagnosing and managing coronary artery disease. Current image processing methods are hindered by the time…

Machine Learning · Computer Science 2021-04-20 Arjun Balaji , Lachlan Kelsey , Kamran Majeed , Carl Schultz , Barry Doyle