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Analyzing volumetric data with rotational invariance or equivariance is an active topic in current research. Existing deep-learning approaches utilize either group convolutional networks limited to discrete rotations or steerable…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Dmitrii Zhemchuzhnikov , Sergei Grudinin

Pretraining on a large number of unlabeled 3D molecules has showcased superiority in various scientific applications. However, prior efforts typically focus on pretraining models in a specific domain, either proteins or small molecules,…

Machine Learning · Computer Science 2025-02-25 Rui Jiao , Xiangzhe Kong , Li Zhang , Ziyang Yu , Fangyuan Ren , Wenjuan Tan , Wenbing Huang , Yang Liu

Many successful deep learning architectures are equivariant to certain transformations in order to conserve parameters and improve generalization: most famously, convolution layers are equivariant to shifts of the input. This approach only…

Machine Learning · Computer Science 2021-03-31 Allan Zhou , Tom Knowles , Chelsea Finn

Equivariance is a nice property to have as it produces much more parameter efficient neural architectures and preserves the structure of the input through the feature mapping. Even though some combinations of transformations might never…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 David W. Romero , Mark Hoogendoorn

Deep generative models are increasingly used for molecular discovery, with most recent approaches relying on equivariant graph neural networks (GNNs) under the assumption that explicit equivariance is essential for generating high-quality…

Machine Learning · Computer Science 2025-07-15 Ewa M. Nowara , Joshua Rackers , Patricia Suriana , Pan Kessel , Max Shen , Andrew Martin Watkins , Michael Maser

Symmetries and equivariance are fundamental to the generalization of neural networks on domains such as images, graphs, and point clouds. Existing work has primarily focused on a small number of groups, such as the translation, rotation,…

Machine Learning · Computer Science 2021-04-20 Marc Finzi , Max Welling , Andrew Gordon Wilson

We explain equivariant neural networks, a notion underlying breakthroughs in machine learning from deep convolutional neural networks for computer vision to AlphaFold 2 for protein structure prediction, without assuming knowledge of…

Machine Learning · Computer Science 2022-11-18 Lek-Heng Lim , Bradley J. Nelson

The translation equivariance of convolutional layers enables convolutional neural networks to generalize well on image problems. While translation equivariance provides a powerful inductive bias for images, we often additionally desire…

Machine Learning · Statistics 2020-09-25 Marc Finzi , Samuel Stanton , Pavel Izmailov , Andrew Gordon Wilson

Many theoretical results in deep learning can be traced to symmetry or equivariance of neural networks under parameter transformations. However, existing analyses are typically problem-specific and focus on first-order consequences such as…

Machine Learning · Computer Science 2025-12-29 Yongyi Yang , Liu Ziyin

While conventional Transformers generally operate on sequence data, they can be used in conjunction with structure models, typically SE(3)-invariant or equivariant graph neural networks (GNNs), for 3D applications such as protein structure…

Machine Learning · Computer Science 2025-08-04 Isaac Ellmen , Constantin Schneider , Matthew I. J. Raybould , Charlotte M. Deane

Recent advances in computational modelling of atomic systems, spanning molecules, proteins, and materials, represent them as geometric graphs with atoms embedded as nodes in 3D Euclidean space. In these graphs, the geometric attributes…

Rotation equivariance is a desirable property in many practical applications such as motion forecasting and 3D perception, where it can offer benefits like sample efficiency, better generalization, and robustness to input perturbations.…

Computer Vision and Pattern Recognition · Computer Science 2023-01-26 Serge Assaad , Carlton Downey , Rami Al-Rfou , Nigamaa Nayakanti , Ben Sapp

Mental rotation -- the ability to compare objects seen from different viewpoints -- is a fundamental example of mental simulation and spatial world modeling in humans. Here we propose a mechanistic model of human mental rotation, leveraging…

Neurons and Cognition · Quantitative Biology 2026-05-29 Raymond Khazoum , Daniela Fernandes , Aleksandr Krylov , Qin Li , Stephane Deny

Designing machine learning architectures for processing neural networks in their raw weight matrix form is a newly introduced research direction. Unfortunately, the unique symmetry structure of deep weight spaces makes this design very…

Machine Learning · Computer Science 2023-06-02 Aviv Navon , Aviv Shamsian , Idan Achituve , Ethan Fetaya , Gal Chechik , Haggai Maron

We introduce a novel architecture for graph networks which is equivariant to any transformation in the coordinate embeddings that preserves the distance between neighbouring nodes. In particular, it is equivariant to the Euclidean and…

Machine Learning · Computer Science 2021-07-13 Francesco Farina , Emma Slade

We consider the conditional generation of 3D drug-like molecules with \textit{explicit control} over molecular properties such as drug-like properties (e.g., Quantitative Estimate of Druglikeness or Synthetic Accessibility score) and…

Machine Learning · Computer Science 2024-12-20 Haoran Liu , Youzhi Luo , Tianxiao Li , James Caverlee , Martin Renqiang Min

PDE-based Group Convolutional Neural Networks (PDE-G-CNNs) use solvers of evolution PDEs as substitutes for the conventional components in G-CNNs. PDE-G-CNNs can offer several benefits simultaneously: fewer parameters, inherent…

Machine Learning · Computer Science 2024-11-21 Gijs Bellaard , Sei Sakata , Bart M. N. Smets , Remco Duits

Equivariant deep learning architectures exploit symmetries in learning problems to improve the sample efficiency of neural-network-based models and their ability to generalise. However, when modelling real-world data, learning problems are…

Machine Learning · Statistics 2024-11-12 Matthew Ashman , Cristiana Diaconu , Adrian Weller , Wessel Bruinsma , Richard E. Turner

Equivariance of linear neural network layers is well studied. In this work, we relax the equivariance condition to only be true in a projective sense. We propose a way to construct a projectively equivariant neural network through building…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Georg Bökman , Axel Flinth , Fredrik Kahl

Group equivariant neural networks have proven effective in modelling a wide range of tasks where the data lives in a classical geometric space and exhibits well-defined group symmetries. However, these networks are not suitable for learning…

Machine Learning · Computer Science 2025-05-26 Edward Pearce-Crump
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