English
Related papers

Related papers: Robust Genomic Prediction and Heritability Estimat…

200 papers

We present a coherent Bayesian framework for selection of the most likely model from the five genetic models (genotypic, additive, dominant, co-dominant, and recessive) commonly used in genetic association studies. The approach uses a…

Methodology · Statistics 2015-04-22 Harold Bae , Thomas Perls , Martin Steinberg , Paola Sebastiani

Recent studies have shown that integrating multimodal data fusion techniques for imaging and genetic features is beneficial for the etiological analysis and predictive diagnosis of Alzheimer's disease (AD). However, there are several…

Genomics · Quantitative Biology 2025-06-03 Lina Qin , Cheng Zhu , Chuqi Zhou , Yukun Huang , Jiayi Zhu , Ping Liang , Jinju Wang , Yixing Huang , Cheng Luo , Dezhong Yao , Ying Tan

The minimum density power divergence estimator (MDPDE) has gained significant attention in the literature of robust inference due to its strong robustness properties and high asymptotic efficiency; it is relatively easy to compute and can…

Statistics Theory · Mathematics 2025-09-16 Suryasis Jana , Subhrajyoty Roy , Ayanendranath Basu , Abhik Ghosh

Having a precise knowledge of the dispersal ability of a population in a heterogeneous environment is of critical importance in agroecology and conservation biology as it can provide management tools to limit the effects of pests or to…

Populations and Evolution · Quantitative Biology 2015-03-19 L. Roques , E. Walker , P. Franck , S. Soubeyrand , E. K. Klein

Modern population genetics studies typically involve genome-wide genotyping of individuals from a diverse network of ancestries. An important, unsolved problem is how to formulate and estimate probabilistic models of observed genotypes that…

Populations and Evolution · Quantitative Biology 2017-01-10 Wei Hao , Minsun Song , John D. Storey

We collect robust proposals given in the field of regression models with heteroscedastic errors. Our motivation stems from the fact that the practitioner frequently faces the confluence of two phenomena in the context of data analysis:…

Methodology · Statistics 2023-11-08 Conceição Amado , Ana M. Bianco , Graciela Boente , Isabel M. Rodrigues

Motivation: The high dimensionality of genomic data calls for the development of specific classification methodologies, especially to prevent over-optimistic predictions. This challenge can be tackled by compression and variable selection,…

Methodology · Statistics 2021-04-10 G. Durif , L. Modolo , J. Michaelsson , J. E. Mold , S. Lambert-Lacroix , F. Picard

Motivation: The discovery of relationships between gene expression measurements and phenotypic responses is hampered by both computational and statistical impediments. Conventional statistical methods are less than ideal because they either…

Methodology · Statistics 2019-07-16 Lei Ding , Daniel J. McDonald

The robustification of pattern recognition techniques has been the subject of intense research in recent years. Despite the multiplicity of papers on the subject, very few articles have deeply explored the topic of robust classification in…

Applications · Statistics 2015-01-06 Necla Gunduz , Ernest Fokoue

Feature matching is an important computer vision task that involves estimating correspondences between two images of a 3D scene, and dense methods estimate all such correspondences. The aim is to learn a robust model, i.e., a model able to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Johan Edstedt , Qiyu Sun , Georg Bökman , Mårten Wadenbäck , Michael Felsberg

The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical…

Methodology · Statistics 2024-09-11 Kaoru Babasaki , Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn

This paper introduces a robust estimation framework based solely on the copula function. We begin by introducing a family of divergence measures tailored for copulas, including the \(\alpha\)-, \(\beta\)-, and \(\gamma\)-copula divergences,…

Methodology · Statistics 2025-09-18 Shinto Eguchi , Shogo Kato

Lightweight inference is critical for biomolecular structure prediction and other downstream tasks, enabling efficient real-world deployment and inference-time scaling for large-scale applications. In this work, we address the challenge of…

Machine Learning · Computer Science 2025-07-17 Chengyue Gong , Xinshi Chen , Yuxuan Zhang , Yuxuan Song , Hao Zhou , Wenzhi Xiao

While deep learning-based classification is generally tackled using standardized approaches, a wide variety of techniques are employed for regression. In computer vision, one particularly popular such technique is that of confidence-based…

Machine Learning · Computer Science 2020-07-21 Fredrik K. Gustafsson , Martin Danelljan , Goutam Bhat , Thomas B. Schön

In this paper, we propose semiparametric efficient estimators of genetic relatedness between two traits in a model-free framework. Most existing methods require specifying certain parametric models involving the traits and genetic variants.…

Methodology · Statistics 2023-06-05 Xu Guo , Yiyuan Qian , Hongwei Shi , Weichao Yang , Niwen Zhou

This paper develops a new family of estimators, the minimum density power divergence estimators (MDPDEs), for the parameters of the one-shot device model as well as a new family of test statistics, Z-type test statistics based on MDPDEs,…

Methodology · Statistics 2017-04-27 N. Balakrishnan , E. Castilla , N. Martin , L. Pardo

Whole and targeted sequencing of human genomes is a promising, increasingly feasible tool for discovering genetic contributions to risk of complex diseases. A key step is calling an individual's genotype from the multiple aligned short read…

Applications · Statistics 2012-06-29 Baiyu Zhou , Alice S. Whittemore

Given genetic variations and various phenotypical traits, such as Magnetic Resonance Imaging (MRI) features, we consider two important and related tasks in biomedical research: i)to select genetic and phenotypical markers for disease…

Machine Learning · Computer Science 2013-10-17 Shandian Zhe , Zenglin Xu , Yuan Qi

The aim of plant breeding trials is often to identify germplasms that are well adapt to target environments. These germplasms are identified through genomic prediction from the analysis of multi-environmental field trial (MET) using linear…

Quantitative Methods · Quantitative Biology 2018-07-20 Emi Tanaka

The Lipschitz constant of the map between the input and output space represented by a neural network is a natural metric for assessing the robustness of the model. We present a new method to constrain the Lipschitz constant of dense deep…

Machine Learning · Computer Science 2023-08-22 Ouail Kitouni , Niklas Nolte , Mike Williams