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Accurate assessment of central hemodynamics is essential for diagnosis and risk stratification, yet it still relies largely on invasive measurements or on indirect reconstructions built from population-averaged transfer functions. While…

Physics-informed neural networks (PINNs) have emerged as a powerful tool for solving inverse problems, especially in cases where no complete information about the system is known and scatter measurements are available. This is especially…

Computational Engineering, Finance, and Science · Computer Science 2023-08-03 Jeremias Garay , Jocelyn Dunstan , Sergio Uribe , Francisco Sahli Costabal

Physics-Informed Neural Networks (PINNs) show significant potential for solving inverse problems, especially when observations are limited and sparse, provided that the relevant physical equations are known. We use PINNs to estimate smooth…

Numerical Analysis · Mathematics 2025-08-06 Moises Sierpe , Ernesto Castillo , Hernan Mella , Felipe Galarce

Physics-Informed Neural Networks (PINNs) integrate machine learning with differential equations to solve forward and inverse problems while ensuring that predictions adhere to physical laws. Physiologically based pharmacokinetic (PBPK)…

Physics-Informed Neural Networks (PINN) are a machine learning tool that can be used to solve direct and inverse problems related to models described by Partial Differential Equations. This paper proposes an adaptive inverse PINN applied to…

Numerical Analysis · Mathematics 2024-11-28 Marco Berardi , Fabio Difonzo , Matteo Icardi

Physics-informed neural networks (PINNs) have recently received much attention due to their capabilities in solving both forward and inverse problems. For training a deep neural network associated with a PINN, one typically constructs a…

Machine Learning · Computer Science 2022-08-26 Pouyan Nasiri , Roozbeh Dargazany

Solving inverse problems in dynamical systems governed by high-dimensional coupled ordinary differential equations (ODEs) is a ubiquitous challenge in scientific machine learning. In many real-world applications, researchers seek to uncover…

Machine Learning · Computer Science 2026-05-06 Zhao Wei , Kenneth Hor Cheng Koh , Sheng Yuan Chin , James Chun Yip Chan , Chin Chun Ooi , Yew-Soon Ong

Physics-Informed Neural Networks (PINNs) are fast becoming an important tool to solve differential equations rapidly and accurately, and to identify the systems parameters that best agree with a given set of measurements. PINNs have been…

This paper introduces a novel approach to solve inverse problems by leveraging deep learning techniques. The objective is to infer unknown parameters that govern a physical system based on observed data. We focus on scenarios where the…

Machine Learning · Computer Science 2023-10-02 Sidney Besnard , Frédéric Jurie , Jalal M. Fadili

The accurate modelling of structural dynamics is crucial across numerous engineering applications, such as Structural Health Monitoring (SHM), seismic analysis, and vibration control. Often, these models originate from physics-based…

Computational Physics · Physics 2024-10-31 Marcus Haywood-Alexander , Giacomo Arcieri , Antonios Kamariotis , Eleni Chatzi

The identification of material parameters occurring in constitutive models has a wide range of applications in practice. One of these applications is the monitoring and assessment of the actual condition of infrastructure buildings, as the…

Machine Learning · Computer Science 2023-06-14 David Anton , Henning Wessels

In this paper, we apply Physics Informed Neural Networks (PINNs) to infer velocity and pressure field from Light Attenuation Technique (LAT) measurements for gravity current induced by lock-exchange. In a PINN model, physical laws are…

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical properties of the tissue. The accurate assessment of active…

Recently, a class of machine learning methods called physics-informed neural networks (PINNs) has been proposed and gained prevalence in solving various scientific computing problems. This approach enables the solution of partial…

Computational Engineering, Finance, and Science · Computer Science 2023-11-06 Chen Xu , Ba Trung Cao , Yong Yuan , Günther Meschke

Physics-informed neural networks (PINNs) offer a promising framework by embedding partial differential equations (PDEs) into the loss function together with measurement data, making them well-suited for inverse problems. However, standard…

Fluid Dynamics · Physics 2026-05-25 Kakeru Ueda , Hiro Wakimura , Satoshi Ii

This work presents a physics-informed neural network (PINN) based framework to model the strain-rate and temperature dependence of the deformation fields in elastic-viscoplastic solids. To avoid unbalanced back-propagated gradients during…

Materials Science · Physics 2022-11-24 Rajat Arora , Pratik Kakkar , Biswadip Dey , Amit Chakraborty

Turbulence remains a problem that is yet to be fully understood, with experimental and numerical studies aiming to fully characterise the statistical properties of turbulent flows. Such studies require huge amount of resources to capture,…

Fluid Dynamics · Physics 2022-05-31 Vijay Kag , Kannabiran Seshasayanan , Venkatesh Gopinath

Vortex-induced vibration (VIV) is a typical nonlinear fluid-structure interaction phenomenon, which widely exists in practical engineering (the flexible riser, the bridge and the aircraft wing, etc). The conventional finite element model…

Fluid Dynamics · Physics 2021-12-30 Hesheng Tang , Hu Yang , Yangyang Liao , Liyu Xie

We present a physics-informed neural network (PINN) approach for the discovery of slow invariant manifolds (SIMs), for the most general class of fast/slow dynamical systems of ODEs. In contrast to other machine learning (ML) approaches that…

Numerical Analysis · Mathematics 2025-06-24 Dimitrios G. Patsatzis , Lucia Russo , Constantinos Siettos

We characterize and remedy a failure mode that may arise from multi-scale dynamics with scale imbalances during training of deep neural networks, such as Physics Informed Neural Networks (PINNs). PINNs are popular machine-learning templates…

Machine Learning · Computer Science 2021-07-05 Suryanarayana Maddu , Dominik Sturm , Christian L. Müller , Ivo F. Sbalzarini
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