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Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. By adopting a simple theoretical framework for intra-cellular chemical reaction dynamics with…

Cell Behavior · Quantitative Biology 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko

Symmetry-breaking instabilities play an important role in understanding the mechanisms underlying the diversity of patterns observed in nature, such as in Turing's reaction--diffusion theory, which connects cellular signalling and transport…

Pattern Formation and Solitons · Physics 2023-12-25 Andrew L. Krause , Eamonn A. Gaffney , Thomas Jun Jewell , Václav Klika , Benjamin J. Walker

A key problem of eukaryotic cell motility is the signaling mechanism of chemoattractant gradient sensing. Recent experiments have revealed the molecular correlate of gradient sensing: Frontness molecules, such as PI3P and Rac, localize at…

Cell Behavior · Quantitative Biology 2007-05-23 Atul Narang

In networks of nonlinear oscillators, symmetries place hard constraints on the system that can be exploited to predict universal dynamical features and steady-states, providing a rare generic organizing principle for far-from-equilibrium…

Pattern Formation and Solitons · Physics 2021-03-02 Ian Hunter , Michael M. Norton , Bolun Chen , Chris Simonetti , Maria Eleni Moustaka , Jonathan Touboul , Seth Fraden

As the consequences of opinion polarization effect our everyday life in more and more aspect, the understanding of its origins and driving forces becomes increasingly important. Here we develop an agent-based network model with realistic…

Physics and Society · Physics 2024-09-26 Zoltan Kovács , Anna Zafeiris , Gergely Palla

Hydrogen-bond networks govern molecular structure and function across chemistry, biology and materials science, yet their deterministic control at the atomic scale remains a central challenge (1-9).Here, we directly visualize how an…

Materials Science · Physics 2026-04-29 Nassar Doudin , Jian Jiang , Chun Tang , Xiao Cheng Zeng , Mohammed Th. Hassan

Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane protrusions and…

Cell Behavior · Quantitative Biology 2022-01-03 E. Moreno , S. Flemming , F. Font , M. Holschneider , C. Beta , S. Alonso

The use of dual polarization in mobile satellite systems is very promising for increasing the channel capacity. Polarized Modulation is proposed in this paper for use in practical systems, by providing simple equations for computing its…

Signal Processing · Electrical Eng. & Systems 2018-07-26 Anxo Tato , Carlos Mosquera , Pol Henarejos , Ana Perez-Neira

Planar cell polarity (PCP), the coherent in-plane polarization of a tissue on multicellular length scales, provides directional information that guides a multitude of developmental processes at cellular and tissue levels. While it is…

Biological Physics · Physics 2020-07-01 Shahriar Shadkhoo , Madhav Mani

Network equilibrium models represent a versatile tool for the analysis of interconnected objects and their relationships. They have been widely employed in both science and engineering to study the behavior of complex systems under various…

Adaptation and Self-Organizing Systems · Physics 2024-10-31 Omar Aloui , David Orden , Nizar Bel Hadj Ali , Landolf Rhode-Barbarigos

Exactly solvable neural network models with asymmetric weights are rare, and exact solutions are available only in some mean-field approaches. In this article we find exact analytical solutions of an asymmetric spin-glass-like model of…

Neurons and Cognition · Quantitative Biology 2017-02-16 Diego Fasoli , Anna Cattani , Stefano Panzeri

We analyze pattern formation on a network of cells where each cell inhibits its neighbors through cell-to-cell contact signaling. The network is modeled as an interconnection of identical dynamical subsystems each of which represents the…

Dynamical Systems · Mathematics 2014-07-25 Ana S. Rufino Ferreira , Murat Arcak

Pattern formation from homogeneity is well-studied, but less is known concerning symmetry-breaking instabilities in heterogeneous media. It is nontrivial to separate observed spatial patterning due to inherent spatial heterogeneity from…

Pattern Formation and Solitons · Physics 2019-12-10 Andrew L. Krause , Václav Klika , Thomas E. Woolley , Eamonn A. Gaffney

The ultrafast formation of strongly bound excitons in two-dimensional semiconductors provide a rich platform for studying fundamental physics as well as developing novel optoelectronic technologies. While extensive research has explored the…

Polarization is a well-documented phenomenon across a wide range of social issues. However, prevailing theories often compartmentalize the examination of herding behavior and opinion convergence within different contexts. In this study, we…

Theoretical Economics · Economics 2024-05-03 Ugo Bolletta , Paolo Pin

A biophysical model of epimorphic regeneration based on a continuum percolation process of fully penetrable disks in two dimensions is proposed. All cells within a randomly chosen disk of the regenerating organism are assumed to receive a…

Biological Physics · Physics 2023-11-06 Vladimir García-Morales

A novel assay based on micropatterning and time-lapse microscopy has been developed for the study of nuclear migration dynamics in cultured mammalian cells. When cultured on 10-20 um wide adhesive stripes, the motility of C6 glioma and…

Cell Behavior · Quantitative Biology 2009-09-29 B. Szabo , Zs. Kornyei , J. Zach , D. Selmeczi , G. Csucs , A. Czirok , T. Vicsek

Cells crawling through tissues migrate inside a complex fibrous environment called the extracellular matrix (ECM), which provides signals regulating motility. Here we investigate one such well-known pathway, involving mutually antagonistic…

Cell Behavior · Quantitative Biology 2017-07-05 William R. Holmes , JinSeok Park , Andre Levchenko , Leah Edelstein-Keshet

Regulation to a well-defined target state is a fundamental requirement for achieving reliable functionality in living systems and maintaining specific non-equilibrium states. The control of certain properties and functionalities of systems…

Soft Condensed Matter · Physics 2024-12-17 Lisa Rohde , Desmond J. Quinn , Diptabrata Paul , Frank Cichos

We consider networks with two types of nodes. The v-nodes, called centers, are hyperconnected and interact one to another via many u-nodes, called satellites. This centralized architecture, widespread in gene networks, realize a bow-tie…

Molecular Networks · Quantitative Biology 2012-03-02 Sergei Vakulenko , Ovidiu Radulescu
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