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Objective: Extracting PICO elements -- Participants, Intervention, Comparison, and Outcomes -- from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the…

Computation and Language · Computer Science 2024-12-30 Fangyi Chen , Gongbo Zhang , Yilu Fang , Yifan Peng , Chunhua Weng

The rapid growth in published clinical trials makes it difficult to maintain up-to-date systematic reviews, which requires finding all relevant trials. This leads to policy and practice decisions based on out-of-date, incomplete, and biased…

Computation and Language · Computer Science 2021-09-07 Shifeng Liu , Yifang Sun , Bing Li , Wei Wang , Florence T. Bourgeois , Adam G. Dunn

In evidence-based medicine (EBM), defining a clinical question in terms of the specific patient problem aids the physicians to efficiently identify appropriate resources and search for the best available evidence for medical treatment. In…

Computation and Language · Computer Science 2019-11-12 Di Jin , Peter Szolovits

In recent years, there has been a surge in the publication of clinical trial reports, making it challenging to conduct systematic reviews. Automatically extracting Population, Intervention, Comparator, and Outcome (PICO) from clinical trial…

Computation and Language · Computer Science 2024-09-17 Madhusudan Ghosh , Shrimon Mukherjee , Asmit Ganguly , Partha Basuchowdhuri , Sudip Kumar Naskar , Debasis Ganguly

The PICO framework (Population, Intervention, Comparison, and Outcome) is usually used to formulate evidence in the medical domain. The major task of PICO extraction is to extract sentences from medical literature and classify them into…

Computation and Language · Computer Science 2020-05-15 Tengteng Zhang , Yiqin Yu , Jing Mei , Zefang Tang , Xiang Zhang , Shaochun Li

Research on overlapped and discontinuous named entity recognition (NER) has received increasing attention. The majority of previous work focuses on either overlapped or discontinuous entities. In this paper, we propose a novel span-based…

Computation and Language · Computer Science 2021-06-29 Fei Li , Zhichao Lin , Meishan Zhang , Donghong Ji

We present PIIBench, a unified benchmark corpus for Personally Identifiable Information (PII) detection in natural language text. Existing resources for PII detection are fragmented across domain-specific corpora with mutually incompatible…

Computation and Language · Computer Science 2026-04-20 Pritesh Jha

This research on data extraction methods applies recent advances in natural language processing to evidence synthesis based on medical texts. Texts of interest include abstracts of clinical trials in English and in multilingual contexts.…

Computation and Language · Computer Science 2020-01-31 Lena Schmidt , Julie Weeds , Julian P. T. Higgins

Extracting entities and relations is an essential task of information extraction. Triplets extracted from a sentence might overlap with each other. Previous methods either did not address the overlapping issues or solved overlapping issues…

Computation and Language · Computer Science 2023-04-07 Hao Zhang

In evidence-based medicine, relevance of medical literature is determined by predefined relevance conditions. The conditions are defined based on PICO elements, namely, Patient, Intervention, Comparator, and Outcome. Hence, PICO annotations…

Information Retrieval · Computer Science 2023-04-26 Grace E. Lee , Aixin Sun

This paper proposes a structure-aware decoding method based on large language models to address the difficulty of traditional approaches in maintaining both semantic integrity and structural consistency in nested and overlapping entity…

Computation and Language · Computer Science 2026-01-29 Zhimin Qiu , Di Wu , Feng Liu , Yuxiao Wang

We present Pix2Cap-COCO, the first panoptic pixel-level caption dataset designed to advance fine-grained visual understanding. To achieve this, we carefully design an automated annotation pipeline that prompts GPT-4V to generate…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Zuyao You , Junke Wang , Lingyu Kong , Bo He , Zuxuan Wu

This paper presents a novel approach to address the Entity Recognition and Linking Challenge at NLPCC 2015. The task involves extracting named entity mentions from short search queries and linking them to entities within a reference Chinese…

Computation and Language · Computer Science 2023-09-14 Di Lu , Zhongping Liang , Caixia Yuan , Xiaojie Wang

Named Entity Recognition (NER) or the extraction of concepts from clinical text is the task of identifying entities in text and slotting them into categories such as problems, treatments, tests, clinical departments, occurrences (such as…

Computation and Language · Computer Science 2022-08-31 Namrata Nath , Sang-Heon Lee , Ivan Lee

In medical documents, it is possible that an entity of interest not only contains a discontiguous sequence of words but also overlaps with another entity. Entities of such structures are intrinsically hard to recognize due to the large…

Computation and Language · Computer Science 2019-09-04 Bailin Wang , Wei Lu

The fundamental process of evidence extraction and synthesis in evidence-based medicine involves extracting PICO (Population, Intervention, Comparison, and Outcome) elements from biomedical literature. However, Outcomes, being the most…

Computation and Language · Computer Science 2025-06-09 Yiliang Zhou , Abigail M. Newbury , Gongbo Zhang , Betina Ross Idnay , Hao Liu , Chunhua Weng , Yifan Peng

Evidence-based medicine (EBM) research has always been of paramount importance. It is important to find appropriate medical theoretical support for the needs from physicians or patients to reduce the occurrence of medical accidents. This…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Bin Qin

De-identification is the task of identifying protected health information (PHI) in the clinical text. Existing neural de-identification models often fail to generalize to a new dataset. We propose a simple yet effective data augmentation…

Computation and Language · Computer Science 2020-10-13 Xiang Yue , Shuang Zhou

We present a corpus of 5,000 richly annotated abstracts of medical articles describing clinical randomized controlled trials. Annotations include demarcations of text spans that describe the Patient population enrolled, the Interventions…

Computation and Language · Computer Science 2018-06-13 Benjamin Nye , Junyi Jessy Li , Roma Patel , Yinfei Yang , Iain J. Marshall , Ani Nenkova , Byron C. Wallace

The core of evidence-based medicine is to read and analyze numerous papers in the medical literature on a specific clinical problem and summarize the authoritative answers to that problem. Currently, to formulate a clear and focused…

Computation and Language · Computer Science 2019-01-25 Xia Yuan , Liao xiaoli , Li Shilei , Shi Qinwen , Wu Jinfa , Li Ke
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