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Dialogue systems for Automatic Differential Diagnosis (ADD) have a wide range of real-life applications. These dialogue systems are promising for providing easy access and reducing medical costs. Building end-to-end ADD dialogue systems…

Computation and Language · Computer Science 2023-08-17 Srija Macherla , Man Luo , Mihir Parmar , Chitta Baral

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and…

Computation and Language · Computer Science 2024-10-08 Xueshen Li , Xinlong Hou , Nirupama Ravi , Ziyi Huang , Yu Gan

Medical dialogue systems (MDS) aim to provide patients with medical services, such as diagnosis and prescription. Since most patients cannot precisely describe their symptoms, dialogue understanding is challenging for MDS. Previous studies…

Computation and Language · Computer Science 2023-05-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Jian Wang , Wenjie Li

Medical dialogue generation aims to generate responses according to a history of dialogue turns between doctors and patients. Unlike open-domain dialogue generation, this requires background knowledge specific to the medical domain.…

Computation and Language · Computer Science 2023-03-16 Chen Tang , Hongbo Zhang , Tyler Loakman , Chenghua Lin , Frank Guerin

Medical dialogue generation aims to provide automatic and accurate responses to assist physicians to obtain diagnosis and treatment suggestions in an efficient manner. In medical dialogues two key characteristics are relevant for response…

Computation and Language · Computer Science 2021-05-14 Dongdong Li , Zhaochun Ren , Pengjie Ren , Zhumin Chen , Miao Fan , Jun Ma , Maarten de Rijke

Diagnostic prediction and clinical reasoning are critical tasks in healthcare applications. While Large Language Models (LLMs) have shown strong capabilities in commonsense reasoning, they still struggle with diagnostic reasoning due to…

Computation and Language · Computer Science 2026-04-28 Yimin Deng , Zhenxi Lin , Yejing Wang , Guoshuai Zhao , Pengyue Jia , Zichuan Fu , Derong Xu , Yefeng Zheng , Xiangyu Zhao , Li Zhu , Xian Wu , Xueming Qian

Conversational diagnosis requires multi-turn history-taking, where an agent asks clarifying questions to refine differential diagnoses under incomplete information. Existing approaches often rely on the parametric knowledge of a model or…

Artificial Intelligence · Computer Science 2026-02-04 Jeongmoon Won , Seungwon Kook , Yohan Jo

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Conversational artificial intelligence has the potential to assist users in preliminary medical consultations, particularly in settings where access to healthcare professionals is limited. However, many existing medical dialogue systems…

Computation and Language · Computer Science 2026-03-26 Shubham Kumar Nigam , Suparnojit Sarkar , Piyush Patel

Automatic differential diagnosis (DDx) is an essential medical task that generates a list of potential diseases as differentials based on patient symptom descriptions. In practice, interpreting these differential diagnoses yields…

Computation and Language · Computer Science 2024-11-08 Shuang Zhou , Mingquan Lin , Sirui Ding , Jiashuo Wang , Genevieve B. Melton , James Zou , Rui Zhang

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

Automated dialogue systems are important applications of artificial intelligence, and traditional systems struggle to understand user emotions and provide empathetic feedback. This study integrates emotional intelligence technology into…

Artificial Intelligence · Computer Science 2024-04-30 Jin Wang , JinFei Wang , Shuying Dai , Jiqiang Yu , Keqin Li

Differential Diagnosis (DDx) is the process of identifying the most likely medical condition among the possible pathologies through the process of elimination based on evidence. An automated process that narrows a large set of pathologies…

Machine Learning · Computer Science 2023-12-05 Mohammad Mahmudul Alam , Edward Raff , Tim Oates , Cynthia Matuszek

Medical dialogue systems (MDS) have emerged as crucial online platforms for enabling multi-turn, context-aware conversations with patients. However, existing MDS often struggle to (1) identify relevant medical knowledge and (2) generate…

Computation and Language · Computer Science 2025-06-13 Hongda Sun , Jiaren Peng , Wenzhong Yang , Liang He , Bo Du , Rui Yan

Medical Dialogue Generation (MDG) is intended to build a medical dialogue system for intelligent consultation, which can communicate with patients in real-time, thereby improving the efficiency of clinical diagnosis with broad application…

Computation and Language · Computer Science 2022-07-11 Bin Li , Encheng Chen , Hongru Liu , Yixuan Weng , Bin Sun , Shutao Li , Yongping Bai , Meiling Hu

Developing conversational agents to interact with patients and provide primary clinical advice has attracted increasing attention due to its huge application potential, especially in the time of COVID-19 Pandemic. However, the training of…

Computation and Language · Computer Science 2022-08-02 Wenge Liu , Jianheng Tang , Yi Cheng , Wenjie Li , Yefeng Zheng , Xiaodan Liang

Medical dialogue generation is an important yet challenging task. Most previous works rely on the attention mechanism and large-scale pretrained language models. However, these methods often fail to acquire pivotal information from the long…

Artificial Intelligence · Computer Science 2022-06-20 Yu Zhao , Yunxin Li , Yuxiang Wu , Baotian Hu , Qingcai Chen , Xiaolong Wang , Yuxin Ding , Min Zhang

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn
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