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The integration of Large Language Models (LLMs) into healthcare holds significant potential to enhance diagnostic accuracy and support medical treatment planning. These AI-driven systems can analyze vast datasets, assisting clinicians in…

Computation and Language · Computer Science 2025-04-15 Diogo Sousa , Guilherme Barbosa , Catarina Rocha , Dulce Oliveira

Large Language Models (LLMs) fine-tuned for specific domains exhibit strong performance; however, the underlying mechanisms by which this fine-tuning reshapes their parametric space are not well understood. Prior works primarily focus on…

Computation and Language · Computer Science 2025-10-13 Eshaan Tanwar , Deepak Nathani , William Yang Wang , Tanmoy Chakraborty

Rare diseases affect over 300 million people worldwide and are characterized by complex care pathways, limited clinical expertise, and substantial unmet communication needs throughout the long patient journey. Recent advances in large…

Computation and Language · Computer Science 2026-04-17 Zaifu Zhan , Yu Hou , Kai Yu , Min Zeng , Anita Burgun , Xiaoyi Chen , Rui Zhang

This paper presents a novel approach to epidemic surveillance, leveraging the power of Artificial Intelligence and Large Language Models (LLMs) for effective interpretation of unstructured big data sources, like the popular ProMED and WHO…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Sergio Consoli , Peter Markov , Nikolaos I. Stilianakis , Lorenzo Bertolini , Antonio Puertas Gallardo , Mario Ceresa

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

Computation and Language · Computer Science 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

The increasing use of tools and solutions based on Large Language Models (LLMs) for various tasks in the medical domain has become a prominent trend. Their use in this highly critical and sensitive domain has thus raised important questions…

Computation and Language · Computer Science 2024-01-09 Jean-Baptiste Excoffier , Tom Roehr , Alexei Figueroa , Jens-Michalis Papaioannou , Keno Bressem , Matthieu Ortala

Epilepsy is a chronic neurological condition characterized by recurrent seizures, with global prevalence estimated at 50 million people worldwide. While progress in high-throughput sequencing has allowed for broad-based transcriptomic…

Genomics · Quantitative Biology 2025-10-02 Muhammad Omer Latif , Hayat Ullah , Muhammad Ali Shafique , Zhihua Dong

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

Large language models (LLMs) are increasingly used in medical fields. In mental health support, the early identification of linguistic markers associated with mental health conditions can provide valuable support to mental health…

Computation and Language · Computer Science 2026-02-03 Konstantinos Skianis , A. Seza Doğruöz , John Pavlopoulos

Artificial intelligence (AI) technology has advanced rapidly in recent years, with large language models (LLMs) emerging as a significant breakthrough. LLMs are increasingly making an impact across various industries, with the medical field…

Artificial Intelligence · Computer Science 2025-09-24 Zhiyu Kan , Wensheng Gan , Zhenlian Qi , Philip S. Yu

Why do we build local large language models (LLMs)? What should a local LLM learn from the target language? Which abilities can be transferred from other languages? Do language-specific scaling laws exist? To explore these research…

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Pre-trained language models (PLMs) have been the de facto paradigm for most natural language processing (NLP) tasks. This also benefits biomedical domain: researchers from informatics, medicine, and computer science (CS) communities propose…

Computation and Language · Computer Science 2023-07-18 Benyou Wang , Qianqian Xie , Jiahuan Pei , Zhihong Chen , Prayag Tiwari , Zhao Li , Jie fu

The advent of large language models (LLMs) has gained tremendous attention over the past year. Previous studies have shown the astonishing performance of LLMs not only in other tasks but also in emotion recognition in terms of accuracy,…

Computation and Language · Computer Science 2023-10-24 Liyizhe Peng , Zixing Zhang , Tao Pang , Jing Han , Huan Zhao , Hao Chen , Björn W. Schuller

Epilepsy is a chronic neurological disorder with a significant prevalence. However, there is still no adequate technological support to enable epilepsy detection and continuous outpatient monitoring in everyday life. Hyperdimensional (HD)…

Neural and Evolutionary Computing · Computer Science 2024-04-30 Una Pale , Tomas Teijeiro , David Atienza

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang