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This work proposes a unified framework to leverage biological information in network propagation-based gene prioritization algorithms. Preliminary results on breast cancer data show significant improvements over state-of-the-art baselines,…

Molecular Networks · Quantitative Biology 2020-02-18 Michele Gentili , Leonardo Martini , Manuela Petti , Lorenzo Farina , Luca Becchetti

In the realm of medical science, the pursuit of enhancing treatment efficacy and patient outcomes continues to drive innovation. This study delves into the integration of biomimicry principles within the domain of Radiation Therapy (RT) to…

Neural and Evolutionary Computing · Computer Science 2025-01-07 Keshav Kumar K. , NVSL Narasimham

This paper studies the problem of globally optimizing a variable of interest that is part of a causal model in which a sequence of interventions can be performed. This problem arises in biology, operational research, communications and,…

Machine Learning · Statistics 2020-05-27 Virginia Aglietti , Xiaoyu Lu , Andrei Paleyes , Javier González

Disease gene prioritization assigns scores to genes or proteins according to their likely relevance for a given disease based on a provided set of seed genes. Here, we describe a new algorithm for disease gene prioritization based on…

Quantum Physics · Physics 2023-11-10 Harto Saarinen , Mark Goldsmith , Rui-Sheng Wang , Joseph Loscalzo , Sabrina Maniscalco

In many nations, diabetes is becoming a significant health problem, and early identification and control are crucial. Using machine learning algorithms to predict diabetes has yielded encouraging results. Using the Pima Indians Diabetes…

Machine Learning · Computer Science 2025-06-13 Mowafaq Salem Alzboon , Mohammad Al-Batah , Muhyeeddin Alqaraleh , Ahmad Abuashour , Ahmad Fuad Bader

Data quality on categorical attribute is a difficult problem that has not received as much attention as numerical counterpart. Our basic idea is to employ association rule for the purpose of data quality measurement. Strong rule generation…

Databases · Computer Science 2012-02-16 J. Malar Vizhi , T. Bhuvaneswari

Purpose: Optimization challenges in science, engineering, and real-world applications often involve complex, high-dimensional, and multimodal search spaces. Traditional optimization methods frequently struggle with local optima entrapment,…

Neural and Evolutionary Computing · Computer Science 2025-11-04 Sreeja Singh , Tamal Ghosh

Breast cancer is not preventable because of its unknown causes. However, its early diagnosis increases patients' recovery chances. Machine learning (ML) can be utilized to improve treatment outcomes in healthcare operations while…

Machine Learning · Computer Science 2024-08-09 Kamyab Karimi , Ali Ghodratnama , Reza Tavakkoli-Moghaddam

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

A significant challenge in nature-inspired algorithmics is the identification of specific characteristics of problems that make them harder (or easier) to solve using specific methods. The hope is that, by identifying these characteristics,…

Neural and Evolutionary Computing · Computer Science 2013-05-06 Matthew Crossley , Andy Nisbet , Martyn Amos

A well-constructed classification model highly depends on input feature subsets from a dataset, which may contain redundant, irrelevant, or noisy features. This challenge can be worse while dealing with medical datasets. The main aim of…

Machine Learning · Computer Science 2019-11-19 Shokooh Taghian , Mohammad H. Nadimi-Shahraki

Prediction of patient survival using high-dimensional multi-omics data requires systematic feature selection methods that ensure predictive performance, sparsity, and reliability for prognostic biomarker discovery. We developed a hybrid…

Genomics · Quantitative Biology 2026-04-15 John Zobolas , Anne-Marie George , Alberto López , Sebastian Fischer , Marc Becker , Tero Aittokallio

We propose and analyse a variant of the recently introduced kinetic based optimization method that incorporates ideas like survival-of-the-fittest and mutation strategies well-known from genetic algorithms. Thus, we provide a first attempt…

Optimization and Control · Mathematics 2024-07-18 Giacomo Albi , Federica Ferrarese , Claudia Totzeck

The selection of the most appropriate algorithm to solve a given problem instance, known as algorithm selection, is driven by the potential to capitalize on the complementary performance of different algorithms across sets of problem…

Machine Learning · Computer Science 2024-06-12 Gjorgjina Cenikj , Ana Nikolikj , Gašper Petelin , Niki van Stein , Carola Doerr , Tome Eftimov

Given genetic variations and various phenotypical traits, such as Magnetic Resonance Imaging (MRI) features, we consider two important and related tasks in biomedical research: i)to select genetic and phenotypical markers for disease…

Machine Learning · Computer Science 2013-10-17 Shandian Zhe , Zenglin Xu , Yuan Qi

Identifying optimal medical treatments to improve survival has long been a critical goal of pharmacoepidemiology. Traditionally, we use an average treatment effect measure to compare outcomes between treatment plans. However, new methods…

The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt…

Computers and Society · Computer Science 2022-12-16 Nidhi Sinha , Teena Jangid , Amit M. Joshi , Saraju P. Mohanty

Associative classification is a recent and rewarding technique which integrates association rule mining and classification to a model for prediction and achieves maximum accuracy. Associative classifiers are especially fit to applications…

Artificial Intelligence · Computer Science 2013-03-26 M. Akhil Jabbar , B L Deekshatulu , Priti Chandra

We consider the optimization of an uncertain objective over continuous and multi-dimensional decision spaces in problems in which we are only provided with observational data. We propose a novel algorithmic framework that is tractable,…

Machine Learning · Statistics 2018-10-30 Dimitris Bertsimas , Christopher McCord

Healthcare is one of the most important aspects of human life. Heart disease is known to be one of the deadliest diseases which is hampering the lives of many people around the world. Heart disease must be detected early so the loss of…

Machine Learning · Computer Science 2024-09-04 Shadab Hussain , Santosh Kumar Nanda , Susmith Barigidad , Shadab Akhtar , Md Suaib , Niranjan K. Ray
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