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Related papers: Biofilm mechanics and patterns

200 papers

Formation of bacterial colonies as biofilm on the surface/interface of various objects has the potential to impact not only human health and disease but also energy and environmental considerations. Biofilms can be regarded as soft…

Fluid Dynamics · Physics 2015-09-15 Pallab Barai , Aloke Kumar , Partha P. Mukherjee

Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) molecules in displays, ordering and dynamics in active…

Quantitative Methods · Quantitative Biology 2022-10-10 Japinder Nijjer , Mrityunjay Kothari , Changhao Li , Thomas Henzel , Qiuting Zhang , Jung-Shen B. Tai , Shuang Zhou , Sulin Zhang , Tal Cohen , Jing Yan

We propose a computational framework to study the growth and spread of bacterial biofilms on interfaces, as well as the action of antibiotics on them. Bacterial membranes are represented by boundaries immersed in a fluid matrix and subject…

Cell Behavior · Quantitative Biology 2022-01-11 Ana Carpio , Rafael Gonzalez-Albaladejo

In some conditions, bacteria self-organise into biofilms, supracellular structures made of a self-produced embedding matrix, mainly composed on polysaccharides, DNA, proteins and lipids. It is known that bacteria change their colony/matrix…

In growing active matter systems, a large collection of engineered or living autonomous units metabolize free energy and create order at different length scales as they proliferate and migrate collectively. One such example is bacterial…

Soft Condensed Matter · Physics 2021-06-15 Japinder Nijjer , Changhao Li , Qiuting Zhang , Haoran Lu , Sulin Zhang , Jing Yan

Bacterial biofilms are among the oldest and most prevalent multicellular life forms on Earth and are increasingly relevant in research areas related to industrial fouling, medicine and biotechnology. The main hurdles to obtaining definitive…

Quantitative Methods · Quantitative Biology 2021-10-20 Mohammad Pousti , MirPouyan Zarabadi , Mehran Abbaszadeh Amirdehi , François Paquet-Mercier , Jesse Greener

Bacterial attachment to a fluid interface can lead to the formation of a film with physicochemical properties that evolve with time. We study the time evolution of interface (micro)mechanics for interfaces between oil and bacterial…

Soft Condensed Matter · Physics 2015-03-26 Liana Vaccari , Daniel Allan , Nima Sharifi-Mood , Aayush Singh , Robert Leheny , Kathleen Stebe

Bacteria often develop distinct phenotypes to adapt to environmental stress. In particular, they can produce biofilms, dense communities of bacteria that live in a complex extracellular matrix. Bacterial biofilms provide a safe haven from…

Quantitative Methods · Quantitative Biology 2025-08-29 Stephen Williams , Daravuth Cheam , Michele K. Nishiguchi , Suzanne S. Sindi , Shilpa Khatri , Erica M. Rutter

Biofilms inhabit a range of environments, such as dental plaques or soil micropores, often characterized by intricate, non-even surfaces. However, the impact of surface irregularities on the population dynamics of biofilms remains elusive…

Populations and Evolution · Quantitative Biology 2023-08-31 Witold Postek , Klaudia Staskiewicz , Elin Lilja , Bartlomiej Waclaw

In this paper we derive a pore-scale model for permeable biofilm formation in a two-dimensional pore. The pore is divided in two phases: water and biofilm. The biofilm is assumed to consist of four components: water, extracellular polymeric…

We derive a physiologically structured multiscale model for biofilm development. The model has components on two spatial scales, which induce different time scales into the problem. The macroscopic behavior of the system is modeled using…

Cell Behavior · Quantitative Biology 2023-02-14 Bruce P. Ayati , Isaac Klapper

In this paper, we derive upscaled equations for modelling biofilm growth in porous media. The resulting macro-scale mathematical models consider permeable multi-species biofilm including water flow, transport, detachment and reactions. The…

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

Quantitative Methods · Quantitative Biology 2007-05-23 Leah R. Johnson

Biofilms are microbial collectives that occupy a diverse array of surfaces. The function and evolution of biofilms are strongly influenced by the spatial arrangement of different strains and species within them, but how spatiotemporal…

Populations and Evolution · Quantitative Biology 2018-07-04 Ricardo Martinez-Garcia , Carey D. Nadell , Raimo Hartmann , Knut Drescher , Juan A. Bonachela

Bacterial biofilms collectively develop distinct and ordered structures, including fibers, bundles, and branches. Often, it is unclear how these structural motifs convey specific advantages to bacterial strains under challenging conditions.…

Soft Condensed Matter · Physics 2022-11-16 Mustafa Basaran , Tevfik Can Yüce , Yusuf Ilker Yaman , Roman Vetter , Askin Kocabas

Many organisms form colonies for a transient period of time to withstand environmental pressure. Bacterial biofilms are a prototypical example of such behavior. Despite significant interest across disciplines, physical mechanisms governing…

Soft Condensed Matter · Physics 2015-09-30 Christoph Weber , Yen Ting Lin , Nicolas Biais , Vasily Zaburdaev

Biofilms are a cluster of bacteria embedded in extracellular polymeric substances (EPS) that contain a complex composition of polysaccharides, proteins, and extracellular DNA (eDNA). Desirable mechanical properties of the biofilms are…

Applied Physics · Physics 2019-01-15 Enrique A. López-Guerra , Hongchen Shen , Santiago D. Solares , Danmeng Shuai

Bacterial biofilms, surface-attached communities of cells, are in some respects similar to colloidal solids; both are densely packed with non-zero yield stresses. However, unlike non-living materials, bacteria reproduce and die, breaking…

Soft Condensed Matter · Physics 2019-01-08 Arben Kalziqi , Siu Lung Ng , David Yanni , Gabi Steinbach , Brian K. Hammer , Peter J. Yunker

Bacteria build multicellular communities termed biofilms, which are often encased in a self-secreted extracellular matrix that gives the community mechanical strength and protection against harsh chemicals. How bacteria assemble distinct…

Biological Physics · Physics 2023-09-27 Jakub A. Kochanowski , Bobby Carroll , Merrill E. Asp , Emma Kaputa , Alison E. Patteson

Biofilms are spatially organized microorganism colonies embedded in a self-produced matrix, conferring to the microbial community resistance to environmental stresses. Motile bacteria have been observed swimming in the matrix of pathogenic…

Quantitative Methods · Quantitative Biology 2022-05-24 Guillaume Ravel , Michel Bergmann , Alain Trubuil , Julien Deschamps , Romain Briandet , Simon Labarthe