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Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

Biological Physics · Physics 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

We present an optimized conductance-based retina microcircuit simulator which transforms light stimuli into a series of graded and spiking action potentials through photo transduction. We use discrete retinal neuron blocks based on a…

Neurons and Cognition · Quantitative Biology 2020-01-16 Jason K. Eshraghian , Seungbum Baek , Wesley Thio , Yulia Sandamirskaya , Herbert H. C. Iu , Wei D. Lu

Recent studies have been using graph theoretical approaches to model complex networks (such as social, infrastructural or biological networks), and how their hardwired circuitry relates to their dynamic evolution in time. Understanding how…

Neurons and Cognition · Quantitative Biology 2015-07-17 Anca Radulescu

Research on network mechanisms and coding properties of grid cells assume that the firing rate of a grid cell in each of its fields is the same. Furthermore, proposed network models predict spatial regularities in the firing of inhibitory…

Neurons and Cognition · Quantitative Biology 2017-01-19 Benjamin Dunn , Daniel Wennberg , Ziwei Huang , Yasser Roudi

The concept of a cell$'$s receptive field is a bedrock in systems neuroscience, and the classical static description of the receptive field has had enormous success in explaining the fundamental mechanisms underlying visual processing.…

Neurons and Cognition · Quantitative Biology 2025-04-10 Ifedayo-EmmanuEL Adeyefa-Olasupo

This work explores Liquid Time-Constant Networks (LTCs) and Closed-form Continuous-time Networks (CfCs) for modeling retinal ganglion cell activity in tiger salamanders across three datasets. Compared to a convolutional baseline and an…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Kacper Dobek , Daniel Jankowski , Krzysztof Krawiec

To compensate for sensory processing delays, the visual system must make predictions to ensure timely and appropriate behaviors. Recent work has found predictive information about the stimulus in neural populations early in vision…

Neurons and Cognition · Quantitative Biology 2018-10-05 Audrey J. Sederberg , Jason N. MacLean , Stephanie E. Palmer

This paper proposed a retinal image segmentation method based on conditional Generative Adversarial Network (cGAN) to segment optic disc. The proposed model consists of two successive networks: generator and discriminator. The generator…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Vivek Kumar Singh , Hatem Rashwan , Farhan Akram , Nidhi Pandey , Md. Mostaf Kamal Sarker , Adel Saleh , Saddam Abdulwahab , Najlaa Maaroof , Santiago Romani , Domenec Puig

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is…

Machine Learning · Statistics 2017-11-15 Qi Yan , Zhaofei Yu , Feng Chen , Jian K. Liu

Neural network models comprising elements which have exclusively excitatory or inhibitory synapses are capable of a wide range of dynamic behavior, including chaos. In this paper, a simple excitatory-inhibitory neural pair, which forms the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Sitabhra Sinha , Jayanta Basak

The visual system is hierarchically organized to process visual information in successive stages. Neural representations vary drastically across the first stages of visual processing: at the output of the retina, ganglion cell receptive…

Neurons and Cognition · Quantitative Biology 2019-01-07 Jack Lindsey , Samuel A. Ocko , Surya Ganguli , Stephane Deny

Thalamic relay cells fire action potentials that transmit information from retina to cortex. The amount of information that spike trains encode is usually estimated from the precision of spike timing with respect to the stimulus. Sensory…

Cell motion and appearance have a strong correlation with cell cycle and disease progression. Many contemporary efforts in machine learning utilize spatio-temporal models to predict a cell's physical state and, consequently, the advancement…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Narita Pandhe , Balazs Rada , Shannon Quinn

A linear neural network is proposed for mamalian vision system in which backward connections from the primary visual cortex (V1) to the lateral geniculate nucleus play a key role. The backward connections control the flow of information…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ted Hesselroth , Klaus Schulten

We present a detailed physiological model of the retina that includes the biochemistry and electrophysiology of phototransduction, neuronal electrical coupling, and the spherical geometry of the eye. The model is a parabolic-elliptic system…

Quantitative Methods · Quantitative Biology 2023-03-09 Belal Abuelnasr , Adam R. Stinchcombe

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

Hippocampal place and time cells encode spatial and temporal aspects of experience. Both have the same neural substrate, but have been modeled as having different functions and mechanistic origins, place cells as continuous attractors, and…

Neurons and Cognition · Quantitative Biology 2026-04-02 Qiaorong S. Yu , Zhaoze Wang , Vijay Balasubramanian

Typical learning-based light field reconstruction methods demand in constructing a large receptive field by deepening the network to capture correspondences between input views. In this paper, we propose a spatial-angular attention network…

Image and Video Processing · Electrical Eng. & Systems 2021-11-24 Gaochang Wu , Yingqian Wang , Yebin Liu , Lu Fang , Tianyou Chai

To gain insight into the neural events responsible for visual perception of static and dynamic optical patterns, we study how neural activation spreads in arrays of inhibition-stabilized neural networks with nearest-neighbor coupling. The…

Neurons and Cognition · Quantitative Biology 2016-09-02 Sergey Savel'ev , Sergei Gepshtein

During early development, waves of activity propagate across the retina and play a key role in the proper wiring of the early visual system. During the stage II these waves are triggered by a transient network of neurons, called Starburst…

Neurons and Cognition · Quantitative Biology 2018-12-19 Dora Matzakou-Karvouniari , Lionel Gil , Elaine Orendorff , Olivier Marre , Serge Picaud , Bruno Cessac