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Communication signals often comprise an array of colors, lines, spots, notes or odors that are arranged in complex patterns, melodies or blends. Receiver perception is assumed to influence preference and thus the evolution of signal design,…
We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…
Studies of human decision-making demonstrate that environmental regularities, such as natural image statistics or intentionally nonuniform stimulus probabilities, can be exploited to improve efficiency (termed `efficient-coding').…
Biological and artificial systems encode information through several complex nonlinear operations, making their exact study a formidable challenge. These internal mechanisms often take place across multiple timescales and process external…
Neural encoding is a field in neuroscience that focuses on characterizing how information from stimuli is encoded in the spiking activity of neurons. When more than one stimulus is present, a theory known as multiplexing posits that neurons…
In the wideband regime, the performance of many of the popular modulation schemes such as code division multiple access and orthogonal frequency division multiplexing falls quickly without channel state information. Obtaining the amount of…
The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…
Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling network components are frequently…
Similar to how differences in the proficiency of the cardiovascular and musculoskeletal system predict an individual's athletic ability, differences in how the same brain region encodes information across individuals may explain their…
To date a number of studies have shown that receptive field shapes of early sensory neurons can be reproduced by optimizing coding efficiency of natural stimulus ensembles. A still unresolved question is whether the efficient coding…
Highly connected recurrent neural networks often produce chaotic dynamics, meaning their precise activity is sensitive to small perturbations. What are the consequences for how such networks encode streams of temporal stimuli? On the one…
A cell routinely responds to one of many competing environmental cues. A fundamental question is whether the cell follows the cue prioritized by its internal signaling network or the cue that carries the most external information. We…
Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic…
Signal transduction, or signal-processing capability, is a fundamental property of nature that manifests universally across systems of different scales -- from quantum behaviour to the biological. This includes the detection of…
In multi-terminal networks, feedback increases the capacity region and helps communication devices to coordinate. In this article, we deepen the relationship between coordination and feedback by considering a point-to-point scenario with an…
Expectations can substantially influence perception. Predictive coding is a theory of sensory processing that aims to explain the neural mechanisms underlying the effect of expectations in sensory processing. Its main assumption is that…
Both action potentials and mechanosensitive signalling are an important communication mechanisms in plants. Considering an information theoretic framework, this paper explores the effective range of multiple action potentials for a long…
Many types of cells can sense external ligand concentrations with cell-surface receptors at extremely high accuracy. Interestingly, ligand-bound receptors are often internalized, a process also known as receptor-mediated endocytosis. While…
Deciphering how genes interpret information from the concentration of transcription factors (TFs) within the cell nucleus remains a fundamental question in gene regulation. Recent advancements have unveiled the heterogeneous distribution of…
We used various analytical and numerical techniques to elucidate signal propagation in a small enzymatic cascade which is subjected to external and internal noise. The nonlinear character of catalytic reactions, which underlie protein…