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This paper is concerned with a non-homogeneous in space and non-local in time random walk model for anomalous subdiffusive transport of cells. Starting with a Markov model involving a structured probability density function, we derive the…

Statistical Mechanics · Physics 2013-02-21 S. Fedotov , A. O. Ivanov , A. Y. Zubarev

The collective migration of epithelial groups of cells plays a central role in processes such as embryo development, wound healing, and cancer invasion. While finite cell clusters are known to collectively migrate in response to external…

We present a foliation-focused critical review of the boundary conditions and dynamics of 4D gravitational theories. A general coordinate transformation introduces a new foliation and changes the hypersurface on which a natural boundary…

High Energy Physics - Theory · Physics 2019-09-04 I. Y. Park

Cell cultures exhibit rich and complex behaviors driven by dynamic metabolic interactions among cells. In this work, we present a model that captures these interactions through a framework inspired by statistical mechanics. Using Monte…

Biological Physics · Physics 2025-09-25 A. R. Batista-Tomás , C. Díaz-Faloh , R. Mulet

The capability of cells to form surface extensions to non-locally probe the surrounding environment plays a key role in cell migration. The existing mathematical models for migration of cell populations driven by this non-local form of…

Cell Behavior · Quantitative Biology 2025-12-24 Tommaso Lorenzi , Nadia Loy , Chiara Villa

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz

We consider transformations between attractor basins of binary cylindrical cellular automata resulting from mutations. A t-point mutation of a state consists in toggling t sites in that state. Results of such mutations are described by a…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Burton Voorhees , Catherine Beauchemin

Migration between different habitats is ubiquitous among biological populations. In this Letter, we study a simple quasispecies model for evolution in two different habitats, with different fitness landscapes, coupled through one-way…

Populations and Evolution · Quantitative Biology 2010-12-23 Bartlomiej Waclaw , Rosalind J. Allen , Martin R. Evans

Step meandering due to a deterministic morphological instability on vicinal surfaces during growth is studied. We investigate nonlinear dynamics of a step model with asymmetric step kinetics, terrace and line diffusion, by means of a…

Statistical Mechanics · Physics 2009-10-31 F. Gillet , O. Pierre-Louis , C. Misbah

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

Tissues and Organs · Quantitative Biology 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

We consider a thin droplet that spreads over a flat, horizontal and chemically heterogeneous surface. The droplet is subjected to changes in its volume though a prescribed, arbitrary spatiotemporal function, which varies slowly and vanishes…

Fluid Dynamics · Physics 2021-12-21 Nikos Savva , Danny Groves

Charge migration is the electronic response that immediately follows localized ionization or excitation in a molecule, before the nuclei have time to move. It typically unfolds on sub-femtosecond time scales and most often corresponds to…

Atomic and Molecular Clusters · Physics 2022-03-07 Francois Mauger , Aderonke Folorunso , Kyle Hamer , Cristel Chandre , Mette Gaarde , Kenneth Lopata , Kenneth Schafer

Stochastic systems often exhibit multiple viable metastable states that are long-lived. Over very long timescales, fluctuations may push the system to transition between them, drastically changing its macroscopic configuration. In realistic…

Statistical Mechanics · Physics 2023-04-14 Tobias Grafke , Alessandro Laio

We introduce a formalism for the geometry of eukaryotic cells and organisms.Cells are taken to be star-convex with good biological reason. This allows for a convenient description of their extent in space as well as all manner of cell…

Other Quantitative Biology · Quantitative Biology 2014-10-03 Nadya Morozova , Robert Penner

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

Signal transduction and cell function are governed by the spatiotemporal organization of membrane-associated molecules. Despite significant advances in visualizing molecular distributions by 3D light microscopy, cell biologists still have…

Quantitative Methods · Quantitative Biology 2023-04-14 Felix Y. Zhou , Andrew Weems , Gabriel M. Gihana , Bingying Chen , Bo-Jui Chang , Meghan Driscoll , Gaudenz Danuser

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

The migration of planets within their nascent protoplanetary disks is a fundamental process that shapes the final architecture of planetary systems. However, studying this phenomenon through direct hydrodynamical simulations is…

Earth and Planetary Astrophysics · Physics 2026-01-14 Ximena S. Ramos , Pablo Benitez-Llambay

As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

Analysis of PDEs · Mathematics 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney
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