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We report on a joint experimental and theoretical study of photoelectron circular dichroism (PECD) in methyloxirane. By detecting O 1s-photoelectrons in coincidence with fragment ions, we deduce the molecule's orientation and photoelectron…

Chiral crystals show promise for spintronic technologies on account of their high spin selectivity, which has led to significant recent interest in quantitative characterization and first-principles prediction of their spin-optoelectronics…

Materials Science · Physics 2023-12-05 Christian Multunas , Andrew Grieder , Junqing Xu , Yuan Ping , Ravishankar Sundararaman

Recently, there is a great interest in studying ultrasensitive detection and characterization of biomolecules using plasmonic particles, because they are of considerable importance in biomedical science and pharmaceutics. So far, all the…

Optics · Physics 2017-12-27 Tong Wu , Weixuan Zhang , Rongyao Wang , Xiangdong Zhang

Recent developments in deep learning have made remarkable progress in speeding up the prediction of quantum chemical (QC) properties by removing the need for expensive electronic structure calculations like density functional theory.…

Chemical Physics · Physics 2023-07-10 Shuqi Lu , Zhifeng Gao , Di He , Linfeng Zhang , Guolin Ke

In the close vicinity of a chiral nanostructure, the circular dichroism of a biomolecule could be greatly enhanced, due to the interaction with the local superchiral fields. Modest enhancement of optical activity using a planar…

Accurate prediction of energy decay curves (EDCs) enables robust analysis of room acoustics and reliable estimation of key parameters. We present a deep learning framework that predicts EDCs directly from room geometry and surface…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-30 Imran Muhammad , Gerald Schuller

Circular Dichroism (CD) can distinguish the handedness of chiral molecules. However, it is typically very weak due to vanishing absorption at low molecular concentrations. Here, we suggest Thermal Circular Dichroism (TCD) for chiral…

Optics · Physics 2024-07-19 Ershad Mohammadi , Giulia Tagliabue

Embedding molecular symmetries into machine-learning models is key for efficient learning of chemico-physical scalar properties, but little evidence on how to extend the same strategy to tensorial quantities exists. Here we formulate a…

Materials Science · Physics 2022-04-27 Vu Ha Anh Nguyen , Alessandro Lunghi

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

Increasing the sensitivity of chiral spectroscopic techniques such as circular dichroism (CD) spectroscopy is a current aspiration in the research field of nanophotonics. Enhancing CD spectroscopy depends upon of two complementary…

Spectroscopic properties of molecules holds great importance for the description of the molecular response under the effect of an UV/Vis electromagnetic radiation. Computationally expensive ab initio (e.g. MultiConfigurational SCF, Coupled…

Electron magnetic chiral dichroism (EMCD) is an emerging tool for quantitative measurements of magnetic properties using the transmission electron microscope (TEM), with the possibility of nanometer resolution. The geometrical conditions,…

Chirality is a fundamental molecular property that governs stereospecific behavior in chemistry and biology. Capturing chirality in machine learning models remains challenging due to the geometric complexity of stereochemical relationships…

Machine Learning · Computer Science 2026-02-10 Runhan Shi , Zhicheng Zhang , Letian Chen , Gufeng Yu , Yang Yang

The shape of a molecule determines its physicochemical and biological properties. However, it is often underrepresented in standard molecular representation learning approaches. Here, we propose using the Euler Characteristic Transform…

Machine Learning · Computer Science 2025-07-08 Victor Toscano-Duran , Florian Rottach , Bastian Rieck

Tandem mass spectra capture fragmentation patterns that provide key structural information about a molecule. Although mass spectrometry is applied in many areas, the vast majority of small molecules lack experimental reference spectra. For…

Machine Learning · Computer Science 2023-05-03 Adamo Young , Bo Wang , Hannes Röst

Circular dichroism (CD) spectroscopy is a useful technique for characterizing chiral molecules. It is more sensitive than total absorption to molecule conformation, and it is routinely used to identify enantiomers. We present here a first…

Chemical Physics · Physics 2022-12-14 Elena Molteni , Giancarlo Cappellini , Davide Sangalli

Early recognition of abnormal rhythms in ECG signals is crucial for monitoring and diagnosing patients' cardiac conditions, increasing the success rate of the treatment. Classifying abnormal rhythms into exact categories is very challenging…

Machine Learning · Computer Science 2019-12-18 Jing Zhang , Jing Tian , Yang Cao , Yuxiang Yang , Xiaobin Xu

Enzyme Commission (EC) numbers, which associate a protein sequence with the biochemical reactions it catalyzes, are essential for the accurate understanding of enzyme functions and cellular metabolism. Many ab-initio computational…

Machine Learning · Computer Science 2023-06-07 Zhenkun Shi , Qianqian Yuan , Ruoyu Wang , Hoaran Li , Xiaoping Liao , Hongwu Ma

Existing molecular machine learning force fields (MLFFs) generally focus on the learning of atoms, molecules, and simple quantum chemical properties (such as energy and force), but ignore the importance of electron density (ED) $\rho(r)$ in…

Chemical Physics · Physics 2025-09-25 Hongxin Xiang , Ke Li , Mingquan Liu , Zhixiang Cheng , Bin Yao , Wenjie Du , Jun Xia , Li Zeng , Xin Jin , Xiangxiang Zeng

Descriptor generation methods using latent representations of encoder$-$decoder (ED) models with SMILES as input are useful because of the continuity of descriptor and restorability to the structure. However, it is not clear how the…

Chemical Physics · Physics 2023-04-14 Shumpei Nemoto , Tadahaya Mizuno , Hiroyuki Kusuhara