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In this note, we apply the theory of stochastic homogenization to find the asymptotic behavior of the solution of a set of Smoluchowski's coagulation-diffusion equations with non-homogeneous Neumann boundary conditions. This system is meant…

Probability · Mathematics 2019-04-26 Bruno Franchi , Martin Heida , Silvia Lorenzani

The asymptotic behavior of the solution of an infinite set of Smoluchowski's discrete coagulation-fragmentation-diffusion equations with non-homogeneous Neumann boundary conditions, defined in a periodically perforated domain, is analyzed.…

Mathematical Physics · Physics 2017-11-17 Laurent Desvillettes , Silvia Lorenzani

We propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We treat brain neurons as a continuous medium and structure them by their degree of malfunctioning. Three…

Biological Physics · Physics 2020-12-29 Michiel Bertsch , Bruno Franchi , Valentina Meschini , Maria Carla Tesi , Andrea Tosin

In this paper we propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We regard brain neurons as a continuous medium, and structure them by their degree of…

Biological Physics · Physics 2017-06-06 Michiel Bertsch , Bruno Franchi , Norina Marcello , Maria Carla Tesi , Andrea Tosin

The Smoluchowski equation is a system of partial differential equations modelling the diffusion and binary coagulation of a large collection of tiny particles. The mass parameter may be indexed either by positive integers, or by positive…

Probability · Mathematics 2008-12-01 Mohammad Reza Yaghouti , Fraydoun Rezakhanlou , Alan Hammond

The aim of this paper is to introduce, analyse and test in practice a new mathematical model describing the interplay between biological tissue atrophy driven by pathogen diffusion, with applications to neurodegenerative disorders. This…

Numerical Analysis · Mathematics 2025-06-23 Valentina Pederzoli , Mattia Corti , Davide Riccobelli , Paola F. Antonietti

Alzheimer's disease is the most common dementia worldwide. Its pathological development is well known to be connected with the accumulation of two toxic proteins: tau protein and amyloid-$\beta$. Mathematical models and numerical…

Numerical Analysis · Mathematics 2024-09-05 Mattia Corti

Alzheimer's disease is characterised by the spreading of misfolded proteins and progressive structural changes in the brain. Despite significant clinical research, understanding how microscopic protein dynamics translate into macroscopic…

Computational Engineering, Finance, and Science · Computer Science 2026-03-23 A. Vazquez-Palomo , C. Betegón , J. Weickenmeier , E. Martínez-Pañeda

A notion of measure solution is formulated for a coagulation-diffusion equation, which is the natural counterpart of Smoluchowski's coagulation equation in a spatially inhomogeneous setting. Some general properties of such solutions are…

Analysis of PDEs · Mathematics 2014-08-25 James Norris

We study a coupled thermo-diffusion system that accounts for the dynamics of hot colloids in periodically heterogeneous media. Our model describes the joint evolution of temperature and colloidal concentrations in a saturated porous…

Analysis of PDEs · Mathematics 2017-04-07 Vo Anh Khoa , Adrian Muntean

We consider Smoluchowski's coagulation equation with a kernel of the form $K = 2 + \epsilon W$, where $W$ is a bounded kernel of homogeneity zero. For small $\epsilon$, we prove that solutions approach a universal, unique self-similar…

Analysis of PDEs · Mathematics 2019-10-18 José A. Cañizo , Sebastian Throm

Quantifying the interaction between a system of interest and its ambient conditions, the memory effect links the states of two distinct Hamiltonians: one for the target system and one for the environment. In this paper, we propose the…

Computational Physics · Physics 2026-02-25 Heeyuen Koh , Shigeo Maruyama

The present paper is concerned with a space-time homogenization problem for nonlinear diffusion equations with periodically oscillating (in space and time) coefficients. Main results consist of a homogenization theorem (i.e., convergence of…

Analysis of PDEs · Mathematics 2020-07-21 Goro Akagi , Tomoyuki Oka

The Smoluchowski coagulation-diffusion PDE is a system of partial differential equations modelling the evolution in time of mass-bearing Brownian particles which are subject to short-range pairwise coagulation. This survey presents a fairly…

Probability · Mathematics 2019-02-14 Alan Hammond

We study the solvability and homogenization of a thermal-diffusion reaction problem posed in a periodically perforated domain. The system describes the motion of populations of hot colloidal particles interacting together via Smoluchowski…

Analysis of PDEs · Mathematics 2014-09-17 Oleh Krehel , Adrian Muntean , Toyohiko Aiki

The spreading of misfolded proteins is a known hallmark in some neurodegenerative diseases, known as proteinopathies. A significant example is the tau protein, associated with many pathologies, such as Alzheimer's. In this work, we discuss…

Numerical Analysis · Mathematics 2025-04-30 Paola F. Antonietti , Mattia Corti

Two-scale homogenization limits of parabolic cross-diffusion systems in a heterogeneous medium with no-flux boundary conditions are proved. The heterogeneity of the medium is reflected in the diffusion coefficients or by the perforated…

Analysis of PDEs · Mathematics 2018-10-18 Ansgar Juengel , Mariya Ptashnyk

We consider a reaction-diffusion-advection problem in a perforated medium, with nonlinear reactions in the bulk and at the microscopic boundary, and low diffusion scaling. The microstructure changes in time; the microstructural evolution is…

Analysis of PDEs · Mathematics 2021-12-02 Markus Gahn , Maria Neuss-Radu , Iulio Sorin Pop

We study the homogenization of a steady diffusion equation in a highly heterogeneous medium made of two subregions separated by a periodic barrier through which the flow is proportional to the jump of the temperature by a layer conductance…

Analysis of PDEs · Mathematics 2008-11-08 Abdelhamid Ainouz

In this paper homogenization of a mathematical model for plant tissue biomechanics is presented. The microscopic model constitutes a strongly coupled system of reaction-diffusion-convection equations for chemical processes in plant cells,…

Analysis of PDEs · Mathematics 2017-08-24 Andrey Piatnitski , Mariya Ptashnyk
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