Related papers: Adaptive Randomization Methods for Sequential Mult…
Adaptive sample size re-estimation (SSR) is a well-established strategy for improving the efficiency and flexibility of clinical trials. Its central challenge is determining whether, and by how much, to increase the sample size at an…
Adapting models pre-trained on large-scale datasets is a proven way to reach strong performance quickly for down-stream tasks. However, the growth of state-of-the-art mod-els makes traditional full fine-tuning unsuitable and difficult,…
Large observational datasets, including those derived from electronic health records, are a valuable resource for medical research but are often affected by missingness, measurement error, and misclassification. Two-phase sampling with…
Background With microarray technology becoming mature and popular, the selection and use of a small number of relevant genes for accurate classification of samples is a hot topic in the circles of biostatistics and bioinformatics. However,…
The dynamics of molecules are governed by rare event transitions between long-lived (metastable) states. To explore these transitions efficiently, many enhanced sampling protocols have been introduced that involve using simulations with…
Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods…
Adaptive algorithms belong to an important class of algorithms used in radar target detection to overcome prior uncertainty of interference covariance. The contamination of the empirical covariance matrix by the useful signal leads to…
Multi-armed bandits are widely used for sequential experimentation in clinical trials, recommendation systems, and online platforms. While regret minimization and valid inference from adaptively collected data have each been studied…
Classical randomized experiments, equipped with randomization-based inference, provide assumption-free inference for treatment effects. They have been the gold standard for drawing causal inference and provide excellent internal validity.…
Precision medicine is an emerging field that takes into account individual heterogeneity to inform better clinical practice. In clinical trials, the evaluation of treatment effect heterogeneity is an important component, and recently, many…
We present a novel spectral learning algorithm for simultaneous localization and mapping (SLAM) from range data with known correspondences. This algorithm is an instance of a general spectral system identification framework, from which it…
Next-generation networks utilize the Open Radio Access Network (O-RAN) architecture to enable dynamic resource management, facilitated by the RAN Intelligent Controller (RIC). While deep reinforcement learning (DRL) models show promise in…
Dynamic treatment regimes (DTRs) are sequences of decision rules to guide treatment assignments in response to a patient's evolving, time-varying disease status. Sequential multiple assignment randomized trials (SMARTs) are considered the…
Estimation and inference for the Average Treatment Effect (ATE) is a cornerstone of causal inference and often serves as the foundation for developing procedures for more complicated settings. Although traditionally analyzed in a batch…
Adaptive Random Testing (ART) has faced criticism, particularly for its computational inefficiency, as highlighted by Arcuri and Briand. Their analysis clarified how ART requires a quadratic number of distance computations as the number of…
Multi-agent reinforcement learning (MARL) is a powerful paradigm for solving cooperative and competitive decision-making problems. While many MARL benchmarks have been proposed, few combine continuous state and action spaces with…
Speculative Decoding is a prominent technique for accelerating the autoregressive inference of large language models (LLMs) by employing a fast draft model to propose candidate token sequences and a large target model to verify them in…
The adaptive rejection sampling (ARS) algorithm is a universal random generator for drawing samples efficiently from a univariate log-concave target probability density function (pdf). ARS generates independent samples from the target via…
The recent surge of building software systems powered by Large Language Models (LLMs) has led to the development of various testing frameworks, primarily focused on treating prompt templates as the unit of testing. Despite the significant…
Rerandomization is an experimental design technique that repeatedly randomizes treatment assignments until covariates are balanced between treatment groups. Rerandomization in the design stage of an experiment can lead to many asymptotic…