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Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Network pruning is widely used to lighten and accelerate neural network models. Structured network pruning discards the whole neuron or filter, leading to accuracy loss. In this work, we propose a novel concept of neuron merging applicable…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Woojeong Kim , Suhyun Kim , Mincheol Park , Geonseok Jeon

Laboratory-grown, engineered living neuronal networks in vitro have emerged in the last years as an experimental technique to understand the collective behavior of neuronal assemblies in relation to their underlying connectivity. An…

Neurons and Cognition · Quantitative Biology 2025-01-09 Akke Mats Houben , Jordi Garcia-Ojalvo , Jordi Soriano

Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Leila Saadatifard , Aryan Mobiny , Pavel Govyadinov , Hien Nguyen , David Mayerich

Humans and most animals inherently possess a distinctive capacity to continually acquire novel experiences and accumulate worldly knowledge over time. This ability, termed continual learning, is also critical for deep neural networks (DNNs)…

Machine Learning · Computer Science 2025-04-22 Geng Liu , Fei Zhu , Rong Feng , Zhiqiang Yi , Shiqi Wang , Gaofeng Meng , Zhaoxiang Zhang

In this project, we have explored machine learning approaches for predicting hearing loss thresholds on the brain's gray matter 3D images. We have solved the problem statement in two phases. In the first phase, we used a 3D CNN model to…

Machine Learning · Computer Science 2024-05-03 Trinath Sai Subhash Reddy Pittala , Uma Maheswara R Meleti , Manasa Thatipamula

Neuromorphic engineering is essentially the development of artificial systems, such as electronic analog circuits that employ information representations found in biological nervous systems. Despite being faster and more accurate than the…

Neural and Evolutionary Computing · Computer Science 2022-09-07 Arvind Subramaniam

Segmentation of cellular structures in electron microscopy (EM) images is fundamental to analyzing the morphology of neurons and glial cells in the healthy and diseased brain tissue. Current neuronal segmentation applications are based on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zewen Zhuo , Ilya Belevich , Ville Leinonen , Eija Jokitalo , Tarja Malm , Alejandra Sierra , Jussi Tohka

Neuron segmentation is the cornerstone of reconstructing comprehensive neuronal connectomes, which is essential for deciphering the functional organization of the brain. The irregular morphology and densely intertwined structures of neurons…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yizhuo Lu , Yanchao Zhang , Jiazheng Liu , Hua Han

Recent developments in photonics include efficient nanoscale optoelectronic components and novel methods for sub-wavelength light manipulation. Here, we explore the potential offered by such devices as a substrate for neuromorphic…

Mesoscale and Nanoscale Physics · Physics 2020-10-15 David O. Winge , Steven Limpert , Heiner Linke , Magnus T. Borgström , Barbara Webb , Stanley Heinze , Anders Mikkelsen

Deep learning-based approaches, particularly graph neural networks (GNNs), have gained prominence in simulating flexible deformations and contacts of solids, due to their ability to handle unstructured physical fields and nonlinear…

Machine Learning · Computer Science 2026-04-07 Zhe Feng , Shilong Tao , Haonan Sun , Shaohan Chen , Zhanxing Zhu , Yunhuai Liu

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Machine Learning · Computer Science 2025-12-16 Chunyu Zou

This work presents a novel method of exploring human brain-visual representations, with a view towards replicating these processes in machines. The core idea is to learn plausible computational and biological representations by correlating…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Simone Palazzo , Concetto Spampinato , Isaak Kavasidis , Daniela Giordano , Joseph Schmidt , Mubarak Shah

Convolutional neural networks are state-of-the-art for various segmentation tasks. While for 2D images these networks are also computationally efficient, 3D convolutions have huge storage requirements and therefore, end-to-end training is…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Christoph Angermann , Markus Haltmeier

Instance segmentation of neurons in volumetric light microscopy images of nervous systems enables groundbreaking research in neuroscience by facilitating joint functional and morphological analyses of neural circuits at cellular resolution.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Lisa Mais , Peter Hirsch , Claire Managan , Ramya Kandarpa , Josef Lorenz Rumberger , Annika Reinke , Lena Maier-Hein , Gudrun Ihrke , Dagmar Kainmueller

The ability to learn and adapt in real time is a central feature of biological systems. Neuromorphic architectures demonstrating such versatility can greatly enhance our ability to efficiently process information at the edge. A key…

Machine Learning · Computer Science 2019-11-12 Sandeep Madireddy , Angel Yanguas-Gil , Prasanna Balaprakash

Deep neural networks have shown excellent performance in stereo matching task. Recently CNN-based methods have shown that stereo matching can be formulated as a supervised learning task. However, less attention is paid on the fusion of…

Computer Vision and Pattern Recognition · Computer Science 2019-06-26 Li Zhang , Quanhong Wang , Haihua Lu , Yong Zhao

Ensemble learning is a widespread technique to improve the prediction performance of neural networks. However, it comes at the price of increased memory and inference time. In this work we propose a novel model fusion technique called…

Machine Learning · Computer Science 2025-02-12 Muhammed Öz , Nicholas Kiefer , Charlotte Debus , Jasmin Hörter , Achim Streit , Markus Götz

Accurate segmentation of medical images is essential for diagnosis and treatment of diseases. These problems are solved by highly complex models, such as deep networks (DN), requiring a large amount of labeled data for training. Thereby,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Dario Sitnik , Ivica Kopriva

Effective learning of asymmetric and local features in images and other data observed on multi-dimensional grids is a challenging objective critical for a wide range of image processing applications involving biomedical and natural images.…

Methodology · Statistics 2022-10-06 Meng Li , Li Ma