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Medical image analysis using deep learning has recently been prevalent, showing great performance for various downstream tasks including medical image segmentation and its sibling, volumetric image segmentation. Particularly, a typical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Ngoc-Vuong Ho , Tan Nguyen , Gia-Han Diep , Ngan Le , Binh-Son Hua

Neuron reconstruction is essential to generate exquisite neuron connectivity map for understanding brain function. Despite the significant amount of effect that has been made on automatic reconstruction methods, manual tracing by…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Donghuan Lu , Sujun Zhao , Peng Xie , Kai Ma , Lijuan Liu , Yefeng Zheng

Deep convolutional neural networks (CNNs) have shown excellent performance in object recognition tasks and dense classification problems such as semantic segmentation. However, training deep neural networks on large and sparse datasets is…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Lorenz Berger , Eoin Hyde , M. Jorge Cardoso , Sebastien Ourselin

In the field of Connectomics, a primary problem is that of 3D neuron segmentation. Although deep learning-based methods have achieved remarkable accuracy, errors still exist, especially in regions with image defects. One common type of…

Computer Vision and Pattern Recognition · Computer Science 2021-12-14 Jules Berman , Dmitri B. Chklovskii , Jingpeng Wu

We present an approach for the joint segmentation and grouping of similar components in anisotropic 3D image data and use it to segment neural tissue in serial sections electron microscopy (EM) images. We first construct a nested set of…

Computer Vision and Pattern Recognition · Computer Science 2011-09-20 Jan Funke , Björn Andres , Fred Hamprecht , Albert Cardona , Matthew Cook

Morphological methods play a crucial role in remote sensing image processing, due to their ability to capture and preserve small structural details. However, most of the existing deep learning models for semantic segmentation are based on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Jun Xie , Wenxiao Li , Faqiang Wang , Liqiang Zhang , Zhengyang Hou , Jun Liu

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Deep Convolutional Neural Networks (CNNs) i.e. Residual Networks (ResNets) have been used successfully for many computer vision tasks, but are difficult to scale to 3D volumetric medical data. Memory is increasingly often the bottleneck…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Kashu Yamazaki , Vidhiwar Singh Rathour , T. Hoang Ngan Le

Sketch-based modeling strives to bring the ease and immediacy of drawing to the 3D world. However, while drawings are easy for humans to create, they are very challenging for computers to interpret due to their sparsity and ambiguity. We…

Graphics · Computer Science 2018-06-20 Johanna Delanoy , Mathieu Aubry , Phillip Isola , Alexei A. Efros , Adrien Bousseau

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

Social and Information Networks · Computer Science 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa

Mitochondria segmentation in electron microscopy images is essential in neuroscience. However, due to the image degradation during the imaging process, the large variety of mitochondrial structures, as well as the presence of noise,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Zhili Li , Xuejin Chen , Jie Zhao , Zhiwei Xiong

Deep neural networks yield promising results in a wide range of computer vision applications, including landmark detection. A major challenge for accurate anatomical landmark detection in volumetric images such as clinical CT scans is that…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Tianyu Ma , Ajay Gupta , Mert R. Sabuncu

Synaptic connectivity detection is a critical task for neural reconstruction from Electron Microscopy (EM) data. Most of the existing algorithms for synapse detection do not identify the cleft location and direction of connectivity…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Toufiq Parag , Daniel Berger , Lee Kamentsky , Benedikt Staffler , Donglai Wei , Moritz Helmstaedter , Jeff W. Lichtman , Hanspeter Pfister

Estimation of optical aberrations from volumetric intensity images is a key step in sensorless adaptive optics for 3D microscopy. Recent approaches based on deep learning promise accurate results at fast processing speeds. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Debayan Saha , Uwe Schmidt , Qinrong Zhang , Aurelien Barbotin , Qi Hu , Na Ji , Martin J. Booth , Martin Weigert , Eugene W. Myers

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Hybrid volumetric medical image segmentation models, combining the advantages of local convolution and global attention, have recently received considerable attention. While mainly focusing on architectural modifications, most existing…

Image and Video Processing · Electrical Eng. & Systems 2024-04-04 Shahina Kunhimon , Abdelrahman Shaker , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Neuropathological analyses benefit from spatially precise volumetric reconstructions that enhance anatomical delineation and improve morphometric accuracy. Our prior work has shown the feasibility of reconstructing 3D brain volumes from 2D…

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

The detailed reconstruction of neural anatomy for connectomics studies requires a combination of resolution and large three-dimensional data capture provided by serial section electron microscopy (ssEM). The convergence of high throughput…

Computer Vision and Pattern Recognition · Computer Science 2017-11-21 Arthur W. Wetzel , Jennifer Bakal , Markus Dittrich , David G. C. Hildebrand , Josh L. Morgan , Jeff W. Lichtman

Electron microscopy (EM) enables the reconstruction of neural circuits at the level of individual synapses, which has been transformative for scientific discoveries. However, due to the complex morphology, an accurate reconstruction of…

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