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Large Language Models (LLMs) have catalyzed significant advancements in Natural Language Processing (NLP), yet they encounter challenges such as hallucination and the need for domain-specific knowledge. To mitigate these, recent…

Computation and Language · Computer Science 2025-07-01 Yucheng Hu , Yuxing Lu

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Language is a ubiquitous tool that is foundational to reasoning and collaboration, ranging from everyday interactions to sophisticated problem-solving tasks. The establishment of a common language can serve as a powerful asset in ensuring…

Artificial Intelligence · Computer Science 2025-08-12 Dom Huh , Prasant Mohapatra

The medical ecosystem consists of the training of new clinicians and researchers, the practice of clinical medicine, and areas of adjacent research. There are many aspects of these domains that could benefit from the application of task…

Computers and Society · Computer Science 2025-07-29 Elisha D. O. Roberson

Large Language Models (LLMs) show potential for medical applications but often lack specialized clinical knowledge. Retrieval Augmented Generation (RAG) allows customization with domain-specific information, making it suitable for…

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large Language Models (LLMs) excel in various Natural Language Processing (NLP) tasks, yet their evaluation, particularly in languages beyond the top $20$, remains inadequate due to existing benchmarks and metrics limitations. Employing…

Computation and Language · Computer Science 2024-02-14 Rishav Hada , Varun Gumma , Adrian de Wynter , Harshita Diddee , Mohamed Ahmed , Monojit Choudhury , Kalika Bali , Sunayana Sitaram

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Large Language Models (LLMs) have achieved remarkable success across a wide array of tasks. Due to the impressive planning and reasoning abilities of LLMs, they have been used as autonomous agents to do many tasks automatically. Recently,…

Computation and Language · Computer Science 2024-04-22 Taicheng Guo , Xiuying Chen , Yaqi Wang , Ruidi Chang , Shichao Pei , Nitesh V. Chawla , Olaf Wiest , Xiangliang Zhang

In the rapidly evolving domain of Natural Language Generation (NLG) evaluation, introducing Large Language Models (LLMs) has opened new avenues for assessing generated content quality, e.g., coherence, creativity, and context relevance.…

Computation and Language · Computer Science 2024-06-13 Zhen Li , Xiaohan Xu , Tao Shen , Can Xu , Jia-Chen Gu , Yuxuan Lai , Chongyang Tao , Shuai Ma

In response to the success of proprietary Large Language Models (LLMs) such as OpenAI's GPT-4, there is a growing interest in developing open, non-proprietary LLMs and AI foundation models (AIFMs) for transparent use in academic,…

Computation and Language · Computer Science 2025-02-10 Mahdi Alkaeed , Sofiat Abioye , Adnan Qayyum , Yosra Magdi Mekki , Ilhem Berrou , Mohamad Abdallah , Ala Al-Fuqaha , Muhammad Bilal , Junaid Qadir

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

In recent years, with the rapid advancement of large language models (LLMs), role-playing language agents (RPLAs) have emerged as a prominent research focus at the intersection of natural language processing (NLP) and human-computer…

Computation and Language · Computer Science 2026-01-16 Ye Wang , Jiaxing Chen , Hongjiang Xiao

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen

Large language models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence technology which is rapidly evolving and promises to aid in medical diagnosis. However, the correctness and the accuracy of their returns has…

Computation and Language · Computer Science 2024-02-07 Dimitrios P. Panagoulias , Maria Virvou , George A. Tsihrintzis

The advent of Large Language Models (LLMs) has significantly transformed the fields of natural and social sciences. Generative Agent-Based Models (GABMs), which utilize large language models in place of real subjects, are gaining increasing…

Physics and Society · Physics 2024-08-20 Yikang Lu , Alberto Aleta , Chunpeng Du , Lei Shi , Yamir Moreno