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Related papers: Benchmarking PathCLIP for Pathology Image Analysis

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Virtual screening, which identifies potential drugs from vast compound databases to bind with a particular protein pocket, is a critical step in AI-assisted drug discovery. Traditional docking methods are highly time-consuming, and can only…

Machine Learning · Computer Science 2023-10-11 Bowen Gao , Bo Qiang , Haichuan Tan , Minsi Ren , Yinjun Jia , Minsi Lu , Jingjing Liu , Weiying Ma , Yanyan Lan

Multi-modal learning has become increasingly popular due to its ability to leverage information from different data sources (e.g., text and images) to improve the model performance. Recently, CLIP has emerged as an effective approach that…

Machine Learning · Computer Science 2024-07-12 Zixiang Chen , Yihe Deng , Yuanzhi Li , Quanquan Gu

We propose a novel taxonomy for bias evaluation of discriminative foundation models, such as Contrastive Language-Pretraining (CLIP), that are used for labeling tasks. We then systematically evaluate existing methods for mitigating bias in…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Junaid Ali , Matthaeus Kleindessner , Florian Wenzel , Kailash Budhathoki , Volkan Cevher , Chris Russell

Despite the success of large-scale pretrained Vision-Language Models (VLMs) especially CLIP in various open-vocabulary tasks, their application to semantic segmentation remains challenging, producing noisy segmentation maps with…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Mengcheng Lan , Chaofeng Chen , Yiping Ke , Xinjiang Wang , Litong Feng , Wayne Zhang

Vision-language models like CLIP have demonstrated remarkable zero-shot capabilities in classification and retrieval. However, these models often struggle with compositional reasoning - the ability to understand the relationships between…

Machine Learning · Computer Science 2025-10-29 Amit Peleg , Naman Deep Singh , Matthias Hein

Contrastive Language-Image Pretraining (CLIP) performs zero-shot image classification by mapping images and textual class representation into a shared embedding space, then retrieving the class closest to the image. This work provides a new…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Fawaz Sammani , Nikos Deligiannis

In this paper, we explore the potential of the Contrastive Language-Image Pretraining (CLIP) model in scene text recognition (STR), and establish a novel Symmetrical Linguistic Feature Distillation framework (named CLIP-OCR) to leverage…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Zixiao Wang , Hongtao Xie , Yuxin Wang , Jianjun Xu , Boqiang Zhang , Yongdong Zhang

CLIP is a seminal multimodal model that maps images and text into a shared representation space through contrastive learning on billions of image-caption pairs. Inspired by the rapid progress of large language models (LLMs), we investigate…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Weiquan Huang , Aoqi Wu , Yifan Yang , Xufang Luo , Yuqing Yang , Usman Naseem , Chunyu Wang , Chunyu Wang , Qi Dai , Xiyang Dai , Dongdong Chen , Chong Luo , Lili Qiu , Liang Hu

Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

Pre-trained vision-language models such as contrastive language-image pre-training (CLIP) have demonstrated a remarkable generalizability, which has enabled a wide range of applications represented by zero-shot classification. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Kazuki Adachi , Shin'ya Yamaguchi , Tomoki Hamagami

Contrastive Language-Image Pre-training (CLIP) has demonstrated impressive capabilities in open-vocabulary classification. The class token in the image encoder is trained to capture the global features to distinguish different text…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Yuqi Lin , Minghao Chen , Kaipeng Zhang , Hengjia Li , Mingming Li , Zheng Yang , Dongqin Lv , Binbin Lin , Haifeng Liu , Deng Cai

Universal visual anomaly detection aims to identify anomalies from novel or unseen vision domains without additional fine-tuning, which is critical in open scenarios. Recent studies have demonstrated that pre-trained vision-language models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Bin-Bin Gao , Yue Zhou , Jiangtao Yan , Yuezhi Cai , Weixi Zhang , Meng Wang , Jun Liu , Yong Liu , Lei Wang , Chengjie Wang

In this paper, we demonstrate that CLIP can also be adapted to downstream tasks where its vision-language alignment is suboptimally learned during pre-training on web-crawled data, all without requiring fine-tuning. We explore the case of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Sohee Kim , Jisu Kang , Dunam Kim , Seokju Lee

Large-scale contrastive vision-language pre-training has shown significant progress in visual representation learning. Unlike traditional visual systems trained by a fixed set of discrete labels, a new paradigm was introduced in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Peng Gao , Shijie Geng , Renrui Zhang , Teli Ma , Rongyao Fang , Yongfeng Zhang , Hongsheng Li , Yu Qiao

Contrastive Language-Image Pre-training (CLIP) stands as one of the most effective and scalable methods for training transferable vision models using paired image and text data. CLIP models are trained using contrastive loss, which…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Lijie Fan , Dilip Krishnan , Phillip Isola , Dina Katabi , Yonglong Tian

Zero-shot vision-language models (VLMs) have shown promise for chest radiograph classification, but their performance is often limited by confounding label co-occurrence, long-tail class imbalance, and transfer instability under domain…

Machine Learning · Computer Science 2026-04-21 Florian Kittler , Sheethal Bhat , Andreas Maier

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

We study the effectiveness of data-balancing for mitigating biases in contrastive language-image pretraining (CLIP), identifying areas of strength and limitation. First, we reaffirm prior conclusions that CLIP models can inadvertently…

Machine Learning · Computer Science 2024-03-08 Ibrahim Alabdulmohsin , Xiao Wang , Andreas Steiner , Priya Goyal , Alexander D'Amour , Xiaohua Zhai

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

An innovative few-shot anomaly detection approach is presented, leveraging the pre-trained CLIP model for medical data, and adapting it for both image-level anomaly classification (AC) and pixel-level anomaly segmentation (AS). A…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahshid Shiri , Cigdem Beyan , Vittorio Murino
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