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Contactless manipulation of small objects is essential for biomedical and chemical applications, such as cell analysis, assisted fertilisation, and precision chemistry. Established methods, including optical, acoustic, and magnetic…

Fluid Dynamics · Physics 2025-07-02 Lucas Amoudruz , Petr Karnakov , Petros Koumoutsakos

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

Fluid Dynamics · Physics 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

The transport of motile entities across modulated energy landscapes plays an important role in a range of phenomena in biology, colloidal science and solid-state physics. Here, an easily implementable strategy that allows for the collective…

Soft Condensed Matter · Physics 2020-03-11 Fernando Martínez-Pedrero , Francisco Ortega , Ramón G. Rubio , Carles Calero

Examples of fluid flows driven by undulating boundaries are found in nature across many different length scales. Even though different driving mechanisms have evolved in distinct environments, they perform essentially the same function:…

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

Understanding the complex patterns in space-time exhibited by active systems has been the subject of much interest in recent times. Complementing this forward problem is the inverse problem of controlling active matter. Here we use optimal…

Soft Condensed Matter · Physics 2022-10-12 Suraj Shankar , Vidya Raju , L. Mahadevan

The independent control of multiple magnetic microrobots under a shared global signal presents critical challenges in biomedical applications such as targeted drug delivery and microsurgeries. Most existing systems only allow all agents to…

Robotics · Computer Science 2025-12-02 Amelia Fernández Seguel , Alejandro I. Maass

We examine the hydrodynamic performance of two cilia beating patterns reconstructed from experimental data. In their respective natural systems, the two beating patterns correspond to: (A) pumping-specialized cilia, and (B)…

Fluid Dynamics · Physics 2015-06-19 Hanliang Guo , Janna Nawroth , Yang Ding , Eva Kanso

Bead-based micro-swimmers are promising systems for payload delivery on the micro-scale. However, the principles underlying their optimal design are not yet fully understood. Here we study a simple device consisting of three…

Fluid Dynamics · Physics 2014-03-03 Jayant Pande , Ana-Sunčana Smith

Most bacteria are driven by the cilia or flagella, consisting of a long filament and a rotary molecular motor through a short flexible hook. The beating pattern of these filaments shows synchronization properties from hydrodynamic…

Fluid Dynamics · Physics 2023-11-23 Weiwei Su , Yuki Izumida , Hiroshi Kori

Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves". These are beautiful examples of emergent dynamics in biology, and are essential for…

Soft Condensed Matter · Physics 2016-04-20 Nicolas Bruot , Pietro Cicuta

Torque-driven microscale swimming robots, or microrotors, hold significant potential in biomedical applications such as targeted drug delivery, minimally invasive surgery, and micromanipulation. This paper addresses the challenge of…

Optimization and Control · Mathematics 2024-09-10 Jake Buzhardt , Phanindra Tallapragada

A remarkable variety of organisms use metachronal coordination (i.e., numerous neighboring appendages beating sequentially with a fixed phase lag) to swim or pump fluid. This coordination strategy is used by microorganisms to break symmetry…

Biological Physics · Physics 2024-07-22 David J. Peterman , Margaret L. Byron

The purpose of this review paper is to present some recent results on the modeling and control of large systems of agents. We focus on particular applications where the agents are capable of independent actions instead of simply reacting to…

Optimization and Control · Mathematics 2023-02-27 Benedetto Piccoli

In this research, the effect of utilizing a micro plasma actuator on controlling the flow through a two-dimensional cylinder is investigated using an advanced electrostatic model. Within this model, by solving two elliptic equations, the…

Fluid Dynamics · Physics 2024-07-16 Javad Omidi

Taking inspiration from the crawling motion of biological cells on a substrate, we consider a physical model of self-propulsion where the spatio-temporal driving can involve both, a mechanical actuation by active force couples, and a…

Soft Condensed Matter · Physics 2024-05-16 Pierre Recho , Lev Truskinovsky

Coordinated cilia are used throughout the natural world for micronscale fluid transport. They are often modelled with regular filament arrays on fixed, planar surfaces. Here, we simulate hundreds of interacting active filaments on spherical…

Fluid Dynamics · Physics 2021-12-01 Timothy A Westwood , Eric E Keaveny

The psychological state of flow has been linked to optimizing human performance. A key condition of flow emergence is a match between the human abilities and complexity of the task. We propose a simple computational model of flow for…

Artificial Intelligence · Computer Science 2014-07-18 Vadim Bulitko

Clockwise rotational movement of isolated single cilia in mice embryo was investigated in vivo. The movement generates leftward fluid flow in the node cavity and plays an important role in left-right determination. The leftward…

Tissues and Organs · Quantitative Biology 2013-05-22 Atsuko Takamatsu , Takuji Ishikawa , Kyosuke Shinohara , Hiroshi Hamada